CAS: 5890-18-6; (S)-1,10-Dimethoxy-5,6,6A,7-Tetrahydro-4H-Dibenzo[de,G]Quinoline-2,9-Diol

该化合物是来自劳拉塞埃家族植物物种的自然产生的碱性物质,其特点是独特的分子结构,其中包括一个有助于其生物活动的双环框架,该化合物以其潜在的药理特性而著称,包括抗微生物和抗炎影响,使其对药化学感兴趣. (+)-Laurolitsine一般是白色到白色以外的固体,在有机溶剂中溶解,反映其亲脂性质.它的立体化学学学(+)指出,它具有能够影响其与生物目标相互作用的具体原子空间安排.对(+)-Laurolitsine的研究继续探索其在药物开发中的潜在应用及其在传统医学中的作用.与许多自然产品一样,提取和净化过程对于以适合进一步研究和应用的形式获得该化合物至关重要.

结构式图片

上下游产品

CAS号475-81-0 (+)-海罂粟碱

合成工艺路线路线简述

    📜(1S)-1-[(4-Hydroxyphenyl)Methyl]-1,2,3,4-Tetrahydroisoquinoline-6,7-Diol 反应生成 去甲异波尔定
    参考文献:Stadler,Richard;Kutchan,Toni M.;Zenk,Meinhart H.,Phytochemistry,28,(1989) N4,C. 1083-1086
    标题:Stadler,Richard;Kutchan,Toni M.;Zenk,Meinhart H.,Phytochemistry,28,(1989) N4,C. 1083-1086

    海关参考信息

    专利信息


    专利号:US-2014315720-A1
    优先权日:2012-10-24
    标 题 :Polysaccharide ester microspheres and methods and articles relating thereto
    发明人:FALLON DENIS G; GARRETT THOMAS S; KIZER LAWTON E; ZAZZARA KAREN L; COMBS MICHAEL T; JOHNSON RICHARD K; DEHART GARY
    权利人:CELANESE ACETATE LLC
    摘要:A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof. Esters thereof may be organic esters (e.g., acetate and the like), inorganic esters (e.g., sulfonates and the like), or combinations thereof. Further, the solids conent of the polysaccharide ester dope, in some instances, may be greater than about 16 wt %.

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    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Yong Z, Ruiqi W, Yanan Y, Ning M, Zhi Z, Yinfeng T, Lin D, Yiying L, Weiying L, Chongming W, Xiaopo Z. Laurolitsine ameliorates type 2 diabetes by regulating the hepatic LKB1-AMPK pathway and gut microbiota. Phytomedicine. 2022 Nov;106:154423. doi: 10.1016/j.phymed.2022.154423. Epub 2022 Aug 31. Erratum in: Phytomedicine. 2023 Jan;108:154533. doi: 10.1016/j.phymed.2022.154533. 29(3):745. doi: 10.3390/molecules29030745.
    3: Yong Z, Ruiqi W, Yanan Y, Ning M, Zhi Z, Yinfeng T, Lin D, Yiying L, Weiying L, Chongming W, Zhang X. Corrigendum to [Laurolitsine ameliorates type 2 diabetes by regulating the hepatic LKB1-AMPK pathway and gut microbiota]. Phytomedicine. 2023 Jan;108:154533. doi: 10.1016/j.phymed.2022.154533. Epub 2022 Nov 7. Erratum for: Phytomedicine. 2022 Nov;106:154423. doi: 10.1016/j.phymed.2022.154423. 59(1):884-892. doi: 10.1080/13880209.2021.1944221.
    5: Hughes DW, Genest K, Skakum W. Alkaloids of Peumus boldus. Isolation of laurotetanine and laurolitsine. J Pharm Sci. 1968 Sep;57(9):1619-20. doi: 10.1002/jps.2600570935. 1(4):100083. doi: 10.1016/j.phyplu.2021.100083. Epub 2021 Jun 6.

    合成参考文献


    摘要:Annales Pharmaceutiques Francaises., 38(537), 1980 []
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