CAS: 39649-71-3; 4-(Hexyloxy)Benzoyl Chloride

该化合物是一种有机化合物,其特征是存在一个附属于六氟氧替代物的苯并基氯化物功能组,这种化合物一般是无色的,可视其纯度和温度而定,可视为淡黄色液体或固体,因其具有反应性而闻名于此,因为乙基氯化物功能组的存在可很容易发生核生殖替代反应.乙基氧组有助于其盐酸性特征,使其在水中溶解性较低,但在有机溶剂中更易溶解.这一化合物经常用于有机合成,特别是在编造酯和其他衍生物时,并可作为各种药品和农用化学品生产的中间体.在处理该物质时,安全防范是不可或缺的,因为它可以是腐蚀性的,并可能导致皮肤,眼睛和呼吸系统受到刺激.建议将它适当储存在远离水分的冷干地方,以保持其稳定性.

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CAS号1142-39-8 4-己氧基苯甲酸 | CAS号111-25-1 1-溴代正己烷 | CAS号50822-54-3 Methyl 4-hexylo... | CAS号99-76-3 尼泊金甲酯 | CAS号99-96-7 4-羟基苯甲酸 | CAS号120-47-8 尼泊金乙酯 | CAS号16782-08-4 四羟基苯甲酸一钾 | CAS号544-10-5 氯(代)正己烷 | CAS号111-27-3 正己醇 | CAS号111833-05-7 4-(4-hexylbenzo... | CAS号52899-68-0 4-(4-己氧基苯甲酰氧基)苯甲酸 | CAS号101772-33-2 4-HEXYLOXYBENZAMIDE | CAS号33905-64-5 4-己氧基苯甲酸-4-羟基苯酯 | CAS号64328-63-8 4-hexoxybenzohy... | CAS号64581-07-3 (4-nitrophenyl)... | CAS号38444-26-7 (4-heptylphenyl...

合成工艺路线路线简述

    📜1-氯己烷置于氢氧化钾,氯化亚砜,N,N-二甲基甲酰胺,Potassium Iodide体系中,用 乙醇,二氯甲烷,水 作为反应溶剂,化学反应 11.0H,反应生成 4-已氧基苯甲酰氯
    参考文献:Synthesis Of Novel Discotic Mesogen Containing Electron-Transportable Oxadiazole Moiety
    标题:Synthesis Of Novel Discotic Mesogen Containing Electron-Transportable Oxadiazole Moiety
    摘要:We Synthesized And Characterized A Novel Discotic Liquid Crystalline Material (Mod) Composed Of 1,3,5-Tri-Substituted Benzene Core And 2-(4-Hexyloxyphenyl)-Oxadiazol-5-Yl Arms. Chemical Structure Of Thob Was Characterized Using H-1-NMR And Mass Spectroscopy And Its Thermal Behavior Was Determined. Using Dsc And Polarized Optical Microscopy. Thob Showed Narrow Mesophase Region At Around 128 Degreesc And Exhibited Nernatic-Like Texture.
    DOI:10.1080/10587250108030113

    海关参考信息

    专利信息


    专利号:US-9662318-B2
    优先权日:2012-07-16
    标题 :Bitopic muscarinic agonists and antagonists and methods of synthesis and use thereof
    发明人:BOULOS JOHN
    权利人:BARRY UNIV INC
    摘要:Compositions for treating a condition associated with activity of a muscarinic receptor (e.g., one or more of M 1 , M 2 , M 3 , M 4 , M 5 ) and for anesthetizing a subject include a bitopic muscarinic antagonist or agonist. A bitopic muscarinic antagonist named JB-D4 was discovered. Additional bitopic muscarinic antagonists discovered and described herein include BK-23, HD-42, HD153, HD-185, KH-5, JM-31 and JM-32. These bitopic ligands and their structural analogs, as well as bitopic muscarinic agonists, may be used as neuromuscular blocking agents (e.g., for use in compositions for anesthetizing a subject) and for the treatment of central nervous system disorders (e.g., Parkinson's disease, Schizophrenia, etc.), Overactive Bladder Syndrome, Chronic Obstructive Pulmonary Disease, asthma, and many other diseases associated with the activation or inhibition of M 1 -M 5 acetylcholine receptors.

    专利号:US-2016136145-A1
    优先权日:2012-07-16
    标 题:Bitopic muscarinic agonists and antagonists and methods of synthesis and use thereof

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    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1007/s002890070053
    摘要:Hernndez SA, Zhou Q, Garay RO, Yang Y. Steric and electronic effects on mesophase stability of segmented liquid crystalline polymers with arylazomethine pendant groups. Polymer Bulletin. 2000 Sep 21;45(1):31–8. doi: 10.1007/s002890070053.
    参考文献:10.1134/s1070427208090243
    摘要:Novikova NS, Kilimenchuk ED, Yarkova MY, Meshkova SB, Topilova ZM. Synthesis and mesomorphism of 1,3-benzenedicarboxylic acid derivatives. Russian Journal of Applied Chemistry. 2008 Sep;81(9):1602–7. doi: 10.1134/s1070427208090243.
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