欧盟法规
C&L通报专利信息
专利号:US-6218600-B1
优先权日:1996-06-12
标题 :Structure and expression of the biotin carboxylase subunit of heteromeric acetyl-CoA carboxylase
发明人:OHLROGGE JOHN B; SHORROSH BASIL; ROESLER KEITH; SHINTANI DAVID; SOMERVILLE CHRIS
权利人:UNIV MICHIGAN STATE
摘要:The gene encoding a biotin carboxylase subunit of heteromeric ACCase has been isolated and sequenced. The cDNA sequence and deduced amino acid sequence is set forth in FIG. 1 and has been accorded GenBank Accession No. L38260. By controlling expression of the gene of the present invention, carboxylation of acetyl-CoA to produce malonyl-CoA may be controlled. Thus, by introducing constructs of the gene of the present invention in sense or anti-sense orientation, carboxylation of acetyl-CoA to produce malonyl-CoA may be increased or decreased. Consequently, fatty acid synthesis in plants and seeds which depends on malonyl-CoA in the plastid may also be controlled.