CAS: 321-55-1; Haloxon
- 英文名称Haloxon
- 中文名称哈洛克酮
- IUPAC名称3-chloro-4-methyl-2-oxo-2H-chromen-7-yl bis(2-chloroethyl) phosphate
- 其它别名Haloxona; 3-Chloro-7-Hydroxy-4-Methylcoumarin Bis(2-Chloroethyl) Phosphate; 96-H-60; Galoxone; Helmirone; Loxon; Luxon; Bis(2-Chloroethyl) (3-Chloro-4-Methyl-2-Oxo-Chromen-7-yl) Phosphate
- CAS编号321-55-1
- MFCD编号:MFCD00010716
- EINECS号:206-289-1
- FDA UNII编号:T8KXA37068
- 分子式:C14H14Cl3O6P分子量:415.59
- 产品CID: 1311932
- 产品分类Inhibitors/Agonists → Anti-infection → Antiparasitic
物理性质
MSDS等安全信息
欧盟法规
ECHA物质ECHA物质C&L通报REACH预注册合成工艺路线路线简述
海关参考信息
- 2905590020-2-氯乙醇
2903110000-一氯甲烷及氯乙烷
2919900090-其他磷酸酯
2908199090-其他酚的卤化衍生物 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
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专利信息
专利号:US-7576037-B2
优先权日:2005-11-18
标题 :Process and apparatus for combinatorial synthesis
发明人：ENGELHARDT JOHNNIE PAUL; GORENSTEIN DAVID G; LUXON BRUCE A
权利人:MEI TECHNOLOGIES INC; BD OF REGENTS UNIV OF TEXAS
摘要:Apparatus and methods are described for split synthesis combinatorial chemistry that provides candidate libraries where an even distribution of theoretical products is obtainable through even mixing during the pooling step, followed by controlled redistribution of the mixed pooled products from the prior addition step into separate synthesis columns, one for each different specie of subunit to be added.
专利号:US-4337274-A
优先权日:1978-05-30
标 题 :Flukicidal compounds
发明人：GORVIN JOHN H
权利人:BURROUGHS WELLCOME CO
摘要:Diphenylethers of the formula: ##STR1## their synthesis, formulations containing them, methods of making such formulations, and their use in the treatment of liver fluke infections in mammals.
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主要参考文献
1: Sinko G, Bosak A, Kovarik Z, Simeon-Rudolf V. Structure-inhibition relationships in the interaction of butyrylcholinesterase with bambuterol, haloxon and their leaving groups. Chem Biol Interact. 2005 Dec 15;157-158:421-3. Review. Review. Review. Review.
合成参考文献
摘要:World Review of Pest Control., 9(119), 1970
摘要:Biochemical Pharmacology., 16(1183), 1967 []
参考文献:10.1007/s00436-001-0535-x
摘要:Harder A. Chemotherapeutic approaches to nematodes: current knowledge and outlook. Parasitol Res. 2002 Mar;88(3):272–7. doi: 10.1007/s00436-001-0535-x.
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