CAS: 28143-91-1; L-Threo-1-Phenyl-2-Amino-1,3-Propanediol

上下游产品

CAS号3306-06-7 1S,2S-(+)-2-ami... | CAS号5267-64-1 D-苯丙氨醇 | CAS号51594-34-4 (1S,2S)-(+)-2-氨... | CAS号90-82-4 伪麻黄碱 | CAS号52075-14-6 (4S,5S)-(-)-4-甲... | CAS号116950-01-7 [2S-(2α,3β,8aβ)... | CAS号35019-66-0 (4S,5S)-2,2-二甲基... | CAS号2153-98-2 (1S,2S)-2-amino...

Trans-4-(Methoxycarbonyl)-5-Phenyl-2-Oxazoline置于盐酸,Sodium Tetrahydroborate,水体系中,用 乙醇,水,异丙醇 用作溶剂,化学反应 3.0H,反应生成(1S,2S)-(+)-2-氨基-1-苯基-1,3-丙二醇
参考文献:Schoellkopf,Ulrich; Scheunemann,Karl-Heinz,Liebigs Annalen Der Chemie,1980,# 8,P. 1348-1349
标题:Schoellkopf,Ulrich; Scheunemann,Karl-Heinz,Liebigs Annalen Der Chemie,1980,# 8,P. 1348-1349

专利信息

专利号:US-5248815-A
优先权日:1991-12-27
标 题 :Stereo-selective synthesis of 2-aryl-propionic acids of high optical purity by using chiral oxazolines
发明人：PARADIES HENRICH H
权利人:PARADIES HENRICH H
摘要:The present invention relates to a stereospecific chemical synthesis of optically pure enantiomers of 2-aryl-alkanoic acids, especially those of the biologically active (S)-aryl-propionic acids, in good chemical yields, useful for preparing large quantities thereof, and having a high optical purity.

专利号:US-5401852-A
优先权日:1989-10-20
标 题:Process for the stereochemical inversion of (2S,3S)-2-amino-3-phenyl-1,3-propanediols into their (2R,3R) enantiomers
发明人：VILLA MARCO; GIORDANO CLAUDIO; CAVICCHIOLI SILVIA; LEVI SILVIO
权利人:ZAMBON SPA
摘要:Intermediates for transforming (2S,3S)-2-amino-3-phenyl-1,3-propanediols into their (2R,3R)-enantiomers are described. The final compounds are useful intermediates for the synthesis of antibiotics like chloramphenicol, Thiamphenicol and Florfenicol.

专利号:US-4939295-A
优先权日:1988-07-26
标 题:Process for the preparation of intermediates for the synthesis of diltiazem
发明人：MERLI VALERIANO; SAGRAMORA GIORGIO; SORIATO GIORGIO
权利人:ZAMBON SPA
摘要:A process for the preparation of (2S,3S)-threo-2-hydroxy-3-(2-aminophenylthio)-3-(4-methoxyphenyl)-propionic acid by resolution of the racemic mixture is described. n The resolution is carried out by using as resolving agent (1S,2S)-threo-1-phenyl-2-amino-1,3-propanediol or (1S,2S)-threo-1-(4-methylthiophenyl)-2-amino-1,3-propanediol.

专利号:US-8778631-B2
优先权日:2009-01-12
标题:Mono charging system for selectively introducing non-native amino acids into proteins using an in vitro protein synthesis system
发明人：VOLOSHIN ALEXEI M; ZAWADA JAMES F; GOLD DANIEL; MURRAY CHRISTOPHER JAMES; ROZZELLE JAMES EDWARD; UTER NATHAN; YIN GANG
权利人:VOLOSHIN ALEXEI M; ZAWADA JAMES F; GOLD DANIEL; MURRAY CHRISTOPHER JAMES; ROZZELLE JAMES EDWARD; UTER NATHAN; YIN GANG; SUTRO BIOPHARMA INC
摘要:This invention provides for a novel means of incorporating non-native amino acids into preselected positions of a protein using a cell-free synthesis system. The methods involve the use of non-orthogonal, native isoaccepting sense tRNAs that are encoded by the genetic code. Such methods allow for numerous non-native amino acids to be incorporated through the use of sense codons without having to rely upon orthogonal tRNA-synthetase pairs.

专利号:WO-9313046-A1
优先权日:1991-12-27
标题:Stereo-selective synthesis of 2-aryl-propionic acids of high optical purity by using chiral oxazolines

专利号:US-7659244-B2
优先权日:2003-11-03
标题:Rapamycin peptides conjugates: synthesis and uses thereof
发明人：SHARMA SANJAY K; WOO THOMAS; NAICKER SELVARAJ
权利人:QUEST PHARMATECH INC
摘要:The present invention relates to new rapamycin derivatives for the inhibition of cell proliferation. The compounds can advantageously target two proteins in dividing cells and interfere with cell cycle. There is thus provided derivatives of rapamycin in which the 42 position of rapamycin is linked to an amino acid or a peptide through a carbamate ester linkage. These rapamycin derivatives can be synthesized by reacting 42-O-(4-Nitrophenoxycarbonyl) rapamycin and an amino acid or a free amino peptide under basic conditions. These rapamycin derivatives can be used to inhibit the cell cycle and are therefore useful for treating cell proliferation disorders.