CAS: 14051-33-3; Benzetimide

上下游产品

2-[1-苄基-4-哌啶基]-2-苯基戊二腈 2-(1-Benzyl-Piperidin-4-yl)-2-Phenyl-Pentanedinitrile 83898-32-2

📜2-[1-苄基-4-哌啶基]-2-苯基戊二腈置于硫酸体系中,用 溶剂黄146 用作溶剂,化学反应生成3-苯基-1'-(苯基甲基)-[3,4'-联哌啶]-2,6-二酮
参考文献:Synthesis And Structure-activity Relationship Of Benzetimide Derivatives As Human Cxcr3 Antagonists
标题:Synthesis And Structure-activity Relationship Of Benzetimide Derivatives As Human Cxcr3 Antagonists
摘要:The Synthesis And Evaluation Of Benzetimide Derivatives Showing Potent Cxcr3 Antagonism Are Described. Optimization Of The Screening Hits Led To The Identification Of More Potent Cxcr3 Antagonists Devoid Of Anti-Cholinergic Activity And Identification Of The Key Pharmacophore Moieties Of The Series. (C) 2008 Elsevier Ltd. All Rights Reserved.
Doi:10.1016/j.Bmcl.2008.07.115

专利信息

专利号:US-2023271983-A1
优先权日:2020-07-29
标题 :Functionalized isonitriles and products, preparation and uses thereof
发明人：SOTELO PÉREZ EDDY; AZUAJE GUERRERO JHONNY ALBERTO; MAJELLARO MARIA
权利人:UNIV SANTIAGO COMPOSTELA
摘要:The present invention relates to functionalized isonitrile compounds, formed by means of multicomponent environmentally friendly reactions, suitable for coupling to functional molecules such as biomolecules, APIs, chromophore and fluorophore molecules. The invention also relates to conjugates between said isonitrile compounds and functional molecules, which are useful in the synthesis of pharmaceutic drugs or tools, fluorescent molecules and labels, polymeric smart materials. The invention furthermore provides a kit for the in-vitro preparation of the functionalized isontrile compounds and conjugates. The invention also contemplates the medical use of said compounds and conjugates.

专利号:US-9650341-B2
优先权日:2010-05-04
标 题 :Process for synthesizing oxidized lactam compounds
发明人：REMENAR JULIUS F; BLUMBERG LAURA COOK; ZEIDAN TAREK A
权利人:ALKERMES PHARMA IRELAND LTD
摘要:The invention provides a method for the synthesis of dehydrogenated lactam drugs of Formula I:

专利号:US-2014315720-A1
优先权日:2012-10-24
标 题 :Polysaccharide ester microspheres and methods and articles relating thereto
发明人：FALLON DENIS G; GARRETT THOMAS S; KIZER LAWTON E; ZAZZARA KAREN L; COMBS MICHAEL T; JOHNSON RICHARD K; DEHART GARY
权利人:CELANESE ACETATE LLC
摘要:A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof. Esters thereof may be organic esters (e.g., acetate and the like), inorganic esters (e.g., sulfonates and the like), or combinations thereof. Further, the solids conent of the polysaccharide ester dope, in some instances, may be greater than about 16 wt %.