CAS: 135729-55-4; Palonosetron Related Compound E
- 英文名称Palonosetron Related Compound E
- 中文名称盐酸帕洛诺司琼杂质1
- IUPAC名称(S)-2-(quinuclidin-3-yl)-2,4,5,6-tetrahydro-1H-benzo[de]isoquinolin-1-one hydrochloride
- 其它别名2-[(3S)-1-Azabicyclo[2.2.2]Oct-3-Yl] 2,4,5,6-Tetrahydro-1H-Benzo[de]Isoquinolin-1-One Hydrochloride; Palonosetron Hydrochloride Impurity 1; Palonosetron Impurity 1 Hcl; Palonosetron Usp Related Compound E; (S)-2-(Quinuclidin-3-yl)-2,4,5,6-Tetrahydro-1H-Benzo[de]Isoquinolin-1-One Hydrochloride; 2-[(3S)-1-Azabicyclo[2.2.2]Octan-3-Yl]-5,6-Dihydro-4~{h}-Benzo[de]Isoquinolin-1-One; Palonosetron-3-Ene Hydrochloride
- CAS编号135729-55-4
- FDA UNII编号:866E0T17RQ
- 分子式:C19H23ClN2O分子量:330.86
- 产品CID: 558962
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- 2902600000-乙苯
2933310010-吡啶
2921199090-其他无环单胺
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主要参考文献
1: Bonhaus DW, Stefanich E, Loury DN, Hsu SA, Eglen RM, Wong EH. Allosteric interactions among agonists and antagonists at 5-hydroxytryptamine3 receptors. J Neurochem. 1995 Jul;65(1):104-10. doi: 10.1046/j.1471-4159.1995.65010104.x. 114(4):851-9. doi: 10.1111/j.1476-5381.1995.tb13282.x.
3: Wong EH, Bonhaus DW, Eglen RM. The identification of heterogeneity of 5-HT3 receptors with [3H]RS-42358-197. Adv Exp Med Biol. 1995;363:97-108. doi: 10.1007/978-1-4615-1857-0_12. 33(3-4):515-26. doi: 10.1016/0028-3908(94)90083-3. 61(5):1927-32. doi: 10.1111/j.1471-4159.1993.tb09835.x. 110(1):119-26. doi: 10.1111/j.1476-5381.1993.tb13780.x.
7: Eglen RM, Lee CH, Smith WL, Johnson LG, Whiting RL, Hegde SS. RS 42358-197, a novel and potent 5-HT3 receptor antagonist, in vitro and in vivo. J Pharmacol Exp Ther. 1993 Aug;266(2):535-43. 234(1):91-9. doi: 10.1016/0014-2999(93)90710-y. 60(3):921-30. doi: 10.1111/j.1471-4159.1993.tb03238.x.
合成参考文献
参考文献:10.1111/j.1471-4159.1993.tb03238.x
摘要:Wong EHF, Bonhaus DW, Wu I, Stefanich E, Eglen RM. Labelling of 5‐Hydroxytryptamine3 Receptors with a Novel 5‐HT3 Receptor Ligand, [3H]RS‐42358–197. Journal of Neurochemistry. 1993 Mar;60(3):921–30. doi: 10.1111/j.1471-4159.1993.tb03238.x.
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