CAS: 105832-38-0; 2-(2,5-Dioxopyrrolidin-1-yl)-1,1,3,3-Tetramethylisouronium Tetrafluoroborate

上下游产品

CAS号632-22-4 四甲基脲 | CAS号67007-51-6 N-hydroxysuccin... | CAS号55750-62-4 3-马来酰亚胺丙酸 N-羟基琥珀酰亚胺酯 | CAS号104425-42-5 N-succinimidyl-... | CAS号104211-94-1 lith°Cholyl-N-h... | CAS号104400-52-4 (2,5-dioxopyrro... | CAS号60444-78-2 4-甲酰苯甲酸N-琥珀酰亚胺酯 | CAS号1262770-54-6 N-琥珀酰亚胺基 4,4,5,... | CAS号209734-74-7 5-羧基-X-罗丹明琥珀酰亚胺酯 | CAS号114932-60-4 1-芘丁酸N-羟基琥珀酰亚胺酯 | CAS号852527-45-8 N-琥珀酰亚胺基 4,4,5,... | CAS号874743-76-7 N-SUCCINIMIDYL-...

1,1,3,3-四甲基脲 反应生成2-琥珀酰亚胺基-1,1,3,3-四甲基脲四氟硼酸酯
参考文献:Knorr,Reinhard;Trzeciak,Arnold;Bannwarth,Willi;Gillessen,Dieter,Tetrahedron Lett.,30,(1989) N5,C. 1927-1930
标题:Knorr,Reinhard;Trzeciak,Arnold;Bannwarth,Willi;Gillessen,Dieter,Tetrahedron Lett.,30,(1989) N5,C. 1927-1930

专利信息

专利号:US-7288661-B2
优先权日:2003-12-10
标 题 :Process for the synthesis of (2S,3aS,7aS)-1-[(S)-alanyl]-octahydro-1H-indole-2-carboxylic acid compounds and application in the synthesis of perindopril
发明人：DUBUFFET THIERRY; LECOUVE JEAN-PIERRE
权利人:SERVIER LAB
摘要:Process for the synthesis of compounds of formula (I): n nwherein R represents a hydrogen atom or a protecting group for the amino function.n n Application in the synthesis of perindopril and pharmaceutically acceptable salts thereof.

专利号:US-7173021-B2
优先权日:2004-09-02
标题:Synthesis of temozolomide esters as potent anticancer pro-drugs for topical and transdermal applications in treatments of cancers
发明人：WANG YONGFENG; CONWAY BARBARA R; SUPPASANSATORN PANASSAYA
权利人:TIANJIN NORTH PHARM SCI TECH C
摘要:This invention relates to the use of temozolomide esters (4-dihydro-3-methyl-4-oxoimidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxylate esters) Formula 1 as potent anticancer pro-drugs for treatment of cancers by topical and transdermal applications, and to a novel process for synthesis of temozolomide esters by a direct esterification of temozolomide acid (3,4-dihydro-3-methyl-4-oxoimidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxylic acid) with a halogeno-aliphatic compound in presence of a base, or with an alcohol in presence of a dehydrate agent

专利号:US-2025101006-A1
优先权日:2022-01-31
标题:Process for the synthesis of pyrazolyl derivatives useful as anti-cancer agents
发明人：BAENZIGER MARKUS; GALLOU FABRICE; GUO FENGFENG; HÄNGGI RUDOLF; HAN ENJIAN; JORDINE GUIDO; LI JIALIANG; LIU WEIPENG; MIAO BUKEYAN; RONG SHAOFENG; SANTANDREA ERNESTO; SCHIRNER PAUL BERND; SHEN XIAODONG; WANG CAN; ZHANG HAO
权利人:NOVARTIS AG
摘要:The invention provides a novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active compounds, especially KRAS G12C inhibitors. The present invention provides a direct enantioselective chemical manufacturing method of making Compound A, or a pharmaceutically acceptable hydrate or solvent thereof: (I). The invention provides a process for preparing Intermediate B6* comprising reacting Intermediate B4* with Intermediate B5* in an atroposelective coupling reaction, using a chiral catalyst.

专利号:US-9096647-B2
优先权日:2008-09-16
标题 :Simplified one-pot synthesis of [18F]SFB for radiolabeling
发明人：OLMA SEBASTIAN; SHEN CLIFTON KWANG-FU
权利人:UNIV CALIFORNIA
摘要:A non-aqueous single pot synthesis of [ 18 F]SFB is set forth. The [ 18 F]SFB produced with this method is then used, for example, to label a peptide or an engineered antibody fragment (diabody) targeting human epidermal growth factor receptor 2 (HER2) as representative examples of labeled compounds for use as an injectable composition to locate abnormal tissue, specifically tumors within an animal or human using a PET scan.

专利号:US-6069248-A
优先权日:1998-08-21
标题 :Process for the synthesis of triazolopyridazine compounds
发明人：BOLDI ARMEN M; JOHNSON CHARLES R
权利人:AXYS PHARM INC
摘要:The present invention provides a process for the synthesis of triazolopyridazine based compounds represented by Formula A: ##STR1## These compounds have utility as angiotensin related antihypertensive agents.

专利号:US-7279583-B2
优先权日:2003-12-10
标题:Process for the synthesis of perindopril and pharmaceutically acceptable salts thereof
发明人：DUBUFFET THIERRY; LECOUVE JEAN-PIERRE
权利人:SERVIER LAB
摘要:Process for the industrial synthesis of perindopril of formula (I): n nand pharmaceutically acceptable salts thereof.