CAS: 104-21-2; 4-Methoxybenzyl Acetate

该化合物是一种芳香酯,常用于口味和香味应用中;它展示了一种甜味,花粉和微果味的芳香味,使其在香水和食品调味中具有价值;该化合物的特点是稳定性和与多种成分的兼容性,确保了配方的一贯性;其中度挥发性允许气味成分的均衡传播;乙酸乙酸乙酰乙酸通过醋酸对乙基乙酸酒精进行酯化合成,产生一种适合工业使用的高纯度产品;其低毒性和对食品及化妆品应用的监管性批准,进一步提高了其效用.

结构式图片

相似化合物

105-13-5 623-05-2 122-91-8

欧盟法规

REACH注册ECHA物质C&L通报REACH预注册

上下游产品

CAS号64-19-7 冰醋酸 | CAS号105-13-5 对甲氧基苄醇 | CAS号108-05-4 乙酸乙烯酯 | CAS号108-24-7 乙酸酐 | CAS号631-61-8 乙酸铵 | CAS号108-22-5 醋酸异丙烯酯 | CAS号14629-56-2 (4-Methoxybenzy... | CAS号75-36-5 乙酰氯 | CAS号104-93-8 4-甲基苯甲醚(MSO) | CAS号63353-51-5 (4-methoxypheny... | CAS号123-11-5 4-甲氧基苯甲醛; 对甲氧基苯... | CAS号100-09-4 对甲氧基苯甲酸 | CAS号93-92-5 乙酸苏合香酯 | CAS号22044-95-7 3-[(4-methoxyph... | CAS号105-13-5 对甲氧基苄醇 | CAS号20574-98-5 4-(4-METHOXYPHE... | CAS号104-20-1 茴香基丙酮 | CAS号104-47-2 对甲氧基苯乙腈 | CAS号3613-53-4 Benzene,1-metho... | CAS号104-93-8 4-甲基苯甲醚(MSO)

合成工艺路线路线简述

    对甲苯甲醚置于sodium Persulfate,Copper Diacetate,Sodium Acetate体系中,用 溶剂黄146 用作溶剂,以77%的收率获得4-甲氧基苄基乙酸酯
    参考文献:Benzyl Acetates By Acetoxylation Of Methylbenzenes Using Peroxydisulfate As Oxidizing Agent
    标题:Benzyl Acetates By Acetoxylation Of Methylbenzenes Using Peroxydisulfate As Oxidizing Agent
    摘要:
    Doi:10.1055/s-1980-29061

    专利信息


    专利号:US-5446158-A
    优先权日:1989-01-11
    标题:Process for synthesis of FK-506 and tricarbonyl intermediates
    发明人:JONES TODD K; MILLS SANDER G; ASKIN DAVID; REAMER ROBERT A; DESMOND RICHARD; TSCHAEN DAVID M; VOLANTE RALPH P; SHINKAI ICHIRO
    权利人:MERCK & CO INC
    摘要:A process is described for the total synthesis of the macrolide immunosuppressant, FK-506, and important tricarbonyl process intermediates thereof. The tricarbonyl intermediates can be produced by the mild oxidation of 2,3-dihydroxy carboxylate compounds containing olefin moieties.

    专利号:US-8829184-B2
    优先权日:2010-04-15
    标题:Intermediates useful for the synthesis of pyrrolobenzodiazepines
    发明人:HOWARD PHILIP WILSON; MASTERSON LUKE; TIBERGHIEN ARNAUD
    权利人:HOWARD PHILIP WILSON; MASTERSON LUKE; TIBERGHIEN ARNAUD; SPIROGEN SARL
    摘要:A compound of formula (I): which is substantially free of any of the corresponding compound of formula (IB): methods of making such compounds, and the further transformation of such compounds.

    专利号:WO-2023177866-A1
    优先权日:2022-03-18
    标题 :Decarboxylative acetoxylation using mn(ii) or mn(iii) reagent for synthesis of 4'-acetoxy- nucleoside and use thereof for synthesis of corresponding 4'-(dimethoxyphosphoryl)methoxy- nucleotide

    专利号:US-6271345-B1
    优先权日:1996-07-03
    标 题 :Enzyme cleavable linker bound to solid phase for organic compound synthesis
    发明人:WALDMANN HERBERT; SAUERBREI BERND; GRETHER UWE
    权利人:BASF AG
    摘要:An enzyme cleavable linker is prepared on which organic compounds are synthesized when the linker is bound to a solid phase. The linker contains a functional group on which a synthesized organic compound is bound when synthesis takes place, and a recognition site for a hydrolytic enzyme. Reacting the linker with the enzyme causes the linker to fragment at a site different from the recognition site to liberate the synthesized organic compound. The solid phase may be a crosslinked polyacrylamide containing an amino group for attaching the linker, and the linker is bound to the solid phase via a spacer. The spacer is attached to the solid phase by an ester, ether, amide or amine linkage, or a sulfide or phosphate linkage. In a specific reaction of forming a solid phase containing the linker, 2-acetoxy-5-hydroxymethylbenzoic acid is attached to an amino group-containing polymer via a spacer followed by conversion to a chloroformic ester.

    专利号:US-4996314-A
    优先权日:1986-03-11
    标题 :6-(disubstituted amino)carbapenem compounds
    发明人:YOSHIOKA TAKEO; CHIDA NORITAKA; WATANABE AZUMA; FUKAGAWA YASUO; ISHIKURA TOMOYUKI
    权利人:SANRAKU INC
    摘要:A compound represented by the formula ##STR1## wherein R 1 represents a lower alkyl group or a lower haloalkyl group; R 2 represents a lower alkyl group, a lower haloalkyl group, an aralkyl group, or a group of the formula --COOR 4 or --SO 2 R 5 in which R 4 represents an aralkyl group or a substituted or unsubstituted alkyl group and R 5 represents an alkyl group or a substituted or unsubstituted aryl group; and R 3 represents a hydrogen atom or a carboxyl protecting group which can be easily split off. This compound is useful in the production of a 6-(disubstituted amino)carbapenem-series antibiotic. n The compounds of the formula ##STR2## wherein R 1 and R 2 are as defined above are important intermediates for the synthesis of the compounds of formula (I) and/or the aforesaid di-(substituted amino) carbapenem-series antibiotics.

    专利号:US-2013035484-A1
    优先权日:2010-04-15
    标 题:Intermediates useful for the synthesis of pyrrolobenzodiazepines
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    合成参考文献


    摘要:Folgueiras-Amador, A. A.; Hodgson, J. W.; Brown, R. C. D., Science of Synthesis: Special Topics, (2021) 1, 424.
    参考文献:10.1038/nchem.1506
    摘要:Over B, Wetzel S, Grütter C, Nakai Y, Renner S, Rauh D, Waldmann H. Natural-product-derived fragments for fragment-based ligand discovery. Nat Chem. 2013 Jan;5(1):21–8. doi: 10.1038/nchem.1506.
    参考文献:10.1007/s12551-018-0423-6
    摘要:Meyer L, von Langermann J, Kragl U. Recent developments in biocatalysis in multiphasic ionic liquid reaction systems. Biophysical Reviews. 2018 Apr 27;10(3):901–10. doi: 10.1007/s12551-018-0423-6.
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