对氨基二苯胺置于钯体系中,用 5,5-Dimethyl-1,3-Cyclohexadiene,环己酮,硝基苯 作为反应溶剂,以40%的收率获得产物n,N'-二苯基-1,4-苯二胺 参考文献:Process For Making Diarylamines 标题:Process For Making Diarylamines 摘要:在铂族金属催化剂和酸性促进剂的存在下,从脂环酮,一种主要芳香胺和氢受体制备二芳胺的改进工艺.
专利号:US-12338202-B2 优先权日:2021-09-10 标 题 :One pot synthesis of urea (meth)acrylates 发明人:BESTGEN SEBASTIAN; BEYER SILVIA 权利人:EVONIK OPERATIONS GMBH 摘要:A one-pot synthesis of polymerizable and acyclic urea (meth)acrylates, preferably mono(meth)acrylates, can be performed via in-situ synthesis of urea alcohols or amines followed by direct reaction with a (meth)acrylate reactive diluent. The urea alcohol/amine is obtained from isocyanates and alcohols, amines, or hydroxyamines. Subsequently, the reaction with the (meth)acrylate reactive diluent takes place and the urea (meth)acrylate is directly obtained either in solution with the reactive diluent, or as a pure material after removal of the reactive diluent.
专利号:US-6329543-B1 优先权日:1999-05-06 标题:Process for synthesis of isobornyl (Meth) acrylate 发明人:KNEBEL JOACHIM; SAAL DORIS 权利人:ROEHM GMBH 摘要:The present invention relates to processes for synthesis of isobornyl (meth)acrylate by reacting camphene with (meth)acrylic acid in the presence of sulfuric acid and at least one compound having inhibiting action. Aqueous sulfuric acid with an acid concentration in the range of 65 to 85 wt % is used. Isobornyl (meth)acrylate can advantageously be distilled from a mixture containing sulfuric acid in the presence of 2,6-di-tert-butyl-alpha-(dialkylamino)-p-cresol.
专利号:US-7799944-B2 优先权日:2003-09-05 标题 :Process for the preparation of (meth)acrylate di-ammonium salts and their use as monomers for the synthesis of polymers 发明人:VANNESTE PIET; LOENDERS RAF; VANDEN EYNDE IVAN; EECKHAOUDT SABINE 权利人:TAMINCO N V 摘要:The invention relates to the preparation of (meth)acrylate di-ammonium salts responding to formula (I) n nwherein R 1 represents hydrogen or methyl, each R 2 , independently, represents an alkyl comprising from 1 to 4 carbon atoms, each R 3 , independently, represents an alkyl or an aralkyl and each X − , independently, represents an anion;n nhaving a high purity and their use as monomers for the synthesis of polymers useful as cationic flocculants.
专利号:US-4910330-A 优先权日:1987-09-25 标题 :Synthesis of sulfonic acids and carboxylic acid ester derivatives thereof 发明人:MCGEE DENNIS E; HALLEN TED S 权利人:UNION OIL CO 摘要:Hydroxy sulfonic acids in general and isethionic acid (2-hydroxy ethyl sulfonic acid) in particular can be prepared at 99+% purity and good yields by the selective oxidation of a precursor hydroxy mercaptan with hydrogen peroxide. The resulting product is pure enough to be used directly in the synthesis of sulfo-acrylic esters which are finding considerable use as stabilizers in producing vinylidene chloride copolymers used for FDA approved packaging films.
专利号:US-4987250-A 优先权日:1987-09-25 标 题:Synthesis of hydroxy sulfonic acids 发明人:MCGEE DENNIS E; HALLEN TED S 权利人:UNION OIL CO 摘要:Hydroxy sulfonic acids in general and isethionic acid (2-hydroxy ethyl sulfonic acid) in particular can be prepared at 99+% purity and good yields by the selective oxidation of a precursor hydroxy mercaptan with hydrogen peroxide. The resulting product is pure enough to be used directly in the synthesis of sulfo-acrylic esters which are finding considerable use as stabilizers in producing vinylidene chloride copolymers used for FDA approved packaging films.
专利号:US-6987186-B2 优先权日:2003-01-28 标 题 :Synthesis of small particle size quinacridone of beta crystal phase 发明人:COLE DAMIEN THURBER; JEGANATHAN SURULIAPPA GOWDER; HE YINGXIA 权利人:CIBA SC HOLDING AG 摘要:The present invention relates to a process for the synthesis of beta-quinacridone by oxidation in the presence of selected additives that promote the formation of the desired crystal phase and particle size.
1: Ahmad F, Leake DS. Antioxidants inhibit low density lipoprotein oxidation less at lysosomal pH: A possible explanation as to why the clinical trials of antioxidants might have failed. Chem Phys Lipids. 2018 Mar 5;213:13-24. doi: 10.1016/j.chemphyslip.2018.03.001. [Epub ahead of print] doi: 10.1021/acs.jpca.7b09851. Epub 2018 Jan 9. doi: 10.1074/jbc.M115.680371. Epub 2015 Dec 8. 4: Al Maruf A, O'Brien P. Flutamide-induced cytotoxicity and oxidative stress in an in vitro rat hepatocyte system. Oxid Med Cell Longev. 2014;2014:398285. doi: 10.1155/2014/398285. Epub 2014 Oct 13. 5: Al Maruf A, Wan L, O'Brien PJ. Evaluation of azathioprine-induced cytotoxicity in an in vitro rat hepatocyte system. Biomed Res Int. 2014;2014:379748. doi: 10.1155/2014/379748. Epub 2014 Jul 1.
合成参考文献
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