CAS: 6626-23-9; 1-(Chloromethyl)-2-Methylnaphthalene

该化合物是一种属于氯化萘衍生物类别的有机化合物,其特点是由两个装有引信的芳香环组成的环形孔,其中含有一个氯甲基组(-CH2Cl)和一个附于氯化萘结构的甲基组(-CH3),该化合物一般没有色,可粉黄黄色液体或固体,视其纯度和温度而定,因其具有可参与核细胞替代反应的氯甲基组的存在而闻名其反应.该化合物用于有机合成,可作为各种化学品生产的中间体,其物理特性包括有机溶剂中的中溶性以及水中的低溶性.安全考虑因素应考虑到,因为它可能对接触健康造成危害,因此需要在实验室和工业环境中进行适当的处理和储存.

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CAS号91-57-6 2-甲基萘 | CAS号7647-01-0 盐酸 | CAS号50-00-0 甲醛 | CAS号7664-38-2 磷酸 | CAS号64-19-7 冰醋酸 | CAS号35699-44-6 2-甲基-1-萘醛 | CAS号573-98-8 1,2-二甲基萘 | CAS号7052-58-6 1,2-bis-(2-meth... | CAS号32277-35-3 1,2-二氢环丁烯并[A]萘 | CAS号69815-53-8 (2-methyl-1-nap... | CAS号72953-44-7 2-(bromomethyl)... | CAS号97585-98-3 4-(chloromethyl... | CAS号476-73-3 benzene-1,2,3,4...

合成工艺路线路线简述

    📜2-甲基萘置于盐酸,聚合甲醛,溶剂黄146体系中,化学反应生成 1-氯甲基-2-甲基萘
    参考文献:Darzens; Levy,Comptes Rendus Hebdomadaires Des Seances De L'Academie Des Sciences,1936,Vol. 202,P. 73
    标题:Darzens; Levy,Comptes Rendus Hebdomadaires Des Seances De L'Academie Des Sciences,1936,Vol. 202,P. 73

    海关参考信息

    专利信息


    专利号:US-8193392-B2
    优先权日:2005-07-29
    标 题:Method for enantioselective synthesis of phosphorus-stereogenic phosphines
    发明人:SCRIBAN CORINA; GLUECK DAVID S
    权利人:SCRIBAN CORINA; GLUECK DAVID S; DARTMOUTH COLLEGE
    摘要:The present invention relates to a process for preparing an enantioenriched phosphorus-stereogenic, tertiary phosphine. Secondary phosphines are contacted with an alkyl halide and base in the presence of a chiral metal catalyst thereby producing the enantioenriched phosphorus-stereogenic, tertiary phosphine for subsequent use in homogeneous catalysis reactions.

    专利号:US-2008193357-A1
    优先权日:2005-07-29
    标 题:Method for Enantioselective Synthesis of Phosphorus-Stereogenic Phosphines

    专利号:US-4528195-A
    优先权日:1978-02-01
    标题:Imidazole derivatives and salts thereof, their synthesis and intermediates and pharmaceutical formulations
    发明人:THOROGOOD PETER B
    权利人:THOROGOOD PETER B
    摘要:Pharmaceutical formulations comprising an imidazole (or pharmaceutically acceptable salt thereof) of formula: ##STR1## wherein (i) A is an aliphatic hydrocarbon residue of from 1 to 4 carbon atoms and R is a naphthyl, tetrahydronaphthyl, heterocyclyl, arylthio, arylalkylthio, aryloxy, arylalkyloxy, arylhydroxymethylene, arylcarbonyl, arylalkylcarbonyl, alkyloxy, alkylthio or a substituted cycloalkyl or cycloalkenyl group or n (ii) A is an --SO 2 -- group and R is aryl or heterocyclyl or n (iii) A is a chemical bond and R is a heterocyclyl or n Some of these imidazoles and salts are novel. n Methods of preparing the imidazoles are disclosed. The imidazoles and their salts are useful in the treatment or prophylaxis of thrombo-embolic conditions, shock and angina pectoris.

    专利号:US-3989746-A
    优先权日:1972-05-11
    标 题 :Substituted naphthyl anthranilic acids
    发明人:NOHARA FUJIO; FUJINAWA TOMOAKI
    权利人:IKEDA MOHANDO CO
    摘要:This invention relates to novel N-(substituted-naphthyl-1)anthranilic acids and their salts, and also to a process for the synthesis of these compounds. These compounds and their pharmaceutically acceptable salts are novel and therapeutically useful as anti-inflammatory agents and analgesics, and they may be orally or non-orally applied, or administered by other methods.

    专利号:CN-103626621-A
    优先权日:2013-12-11
    标 题:A new method for the synthesis of 1,2-dihydrocyclobuteno[α]naphthalene

    专利号:WO-2007016264-A2
    优先权日:2005-07-29
    标题:Method for enantioselective synthesis of phosphorus-stereogenic phosphines

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    合成参考文献


    参考文献:10.1016/j.saa.2011.09.001
    摘要:Nagabalasubramanian PB, Karabacak M, Periandy S. Molecular structure, polarizability, hyperpolarizability analysis and spectroscopic characterization of 1-(chloromethyl)-2-methylnaphthalene with experimental (FT-IR and FT-Raman) techniques and quantum chemical calculations. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2012 Jan;85(1):43–52. doi: 10.1016/j.saa.2011.09.001.
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