专利号:US-5139940-A 优先权日:1989-10-26 标题 :Activation compounds and methods of synthesis of activation compounds 发明人:ISAACS STEPHEN T; CIMINO GEORGE D; METCHETTE KENNETH C; TESSMAN JOHN W 权利人:ISAACS STEPHEN T; CIMINO GOERGE D; METCHETTE KENNETH C; TESSMAN JOHN W 摘要:The invention is directed to isopsoralen compound compositions that contain a variety of substitutions which yet permit their binding to nucleic acid polymers. Reaction conditions that activate these bound isopsoralens results in covalent crosslinking to the nucleic acid polymers. The resultant complex is inhibited from being a template for the template-directed enzymatic synthesis of a complementary nucleic acid polymer. Beside the isopsoralens compositions, the invention includes their synthesis, the nucleic acid complex production and detection, and the above inhibitory method of use of the isopsoralens.
专利号:US-2003162992-A1 优先权日:2001-12-14 标 题 :Preparation of intermediates useful in the synthesis of antiviral nucleosides 发明人:WATANABE KYOICHI A; DU JINFA 摘要:The present invention is an efficient process for the manufacture of α-acyloxyacetaldehyde, a key intermediate in the synthesis of 1,3-oxathiolane and 1,3-dioxolane nucleosides.
专利号:US-2018265547-A1 优先权日:2014-07-18 标 题 :Z-selective olefin metathesis of peptides 发明人:MANGOLD SHANE L; GRUBBS ROBERT H 权利人:CALIFORNIA INST OF TECHN 摘要:The invention relates generally to the synthesis of modified amino acids and modified peptides in the presence of cyclometalated catalysts. The invention has utility in the fields of catalysis, organic synthesis, polymer chemistry, and industrial and fine chemicals chemistry.
专利号:US-12304922-B1 优先权日:2021-12-09 标题:Low pressure process for synthesis of Pt(PF3)4 involving a soluble intermediate and storage of obtained Pt(PF3)4 发明人:NIKIFOROV GRIGORY; BLASCO NICOLAS 权利人:AIR LIQUIDE 摘要:A method for synthesis of Pt(PF3)4 (CAS #19529-53-4), the method comprising the steps of forming a suspension of a platinum precursor Pt(Hal)2, wherein Hal=F, Cl, Br or I, and a metal powder in a solvent, introducing excess amount of PF3 into the suspension of Pt(Hal)2 and the metal powder, forming a soluble reaction intermediate Pt(Hal)2(PF3)x in the solvent through a reaction between PF3 and Pt(Hal)2, wherein Hal=F, Cl, Br or I, x=1, 2, under a reaction condition, and forming Pt(PF3)4 from a reaction between Pt(Hal)2(PF3)x, the metal powder and the excess of PF3 in the solvent.
专利号:US-5973161-A 优先权日:1996-03-18 标 题:Enantioselective synthesis of cyclopentenes 发明人:CRIMMINS MICHAEL T 权利人:UNIV NORTH CAROLINA 摘要:Methods of synthesizing compounds of the Formula V: ##STR1## wherein X c is a chiral auxiliary, m is from 1 to 4, and R 8 is hydrogen or --OH, are provided. n Additionally, methods of synthesizing compounds of the Formula XII: ##STR2## wherein m is from 1-4; B is hydrogen or a blocking group; and R 13 is a leaving group or a compound of formula R 14 --N--R 15 ; n wherein R 14 is hydrogen or branched or straight-chain C1-C6 alkyl; and R 15 is hydrogen, C3-C8 cycloalkyl, or branched or straight-chain alkyl; n are also provided. Novel compounds useful in the synthesis of cyclopentenes and carbocyclic nucleosides are further provided.
专利号:WO-2009135600-A1 优先权日:2008-05-07 标题:Catalysts for the synthesis of polyurethanes 发明人:LINDNER STEFAN; BAHNMUELLER STEFAN; SCHMIDT AXEL; WEIKARD JAN; BUCHMEISER MICHAEL; BANTU BHASKER; FRIEDERICHS WOLFGANG; KRAUSE JENS; REITER STEPHAN 权利人:BAYER MATERIALSCIENCE AG; LINDNER STEFAN; BAHNMUELLER STEFAN; SCHMIDT AXEL; WEIKARD JAN; BUCHMEISER MICHAEL; BANTU BHASKER; FRIEDERICHS WOLFGANG; KRAUSE JENS; REITER STEPHAN 摘要:The invention relates to novel catalysts for the synthesis of polyurethanes, represented by general formula (I) or (II), or compounds obtained by reacting a metal salt of the metals magnesium, calcium, yttrium, lanthanum, titanium, zirconium, manganese, iron, cobalt, zinc, aluminium, tin, comprising an anion from the group fluoride, chloride, bromide, sulphonate, trifluoromethanesulphonate, methanesulphonate, benzolsulphonate, para-toluenesulphonate, carboxy-C1-C10-alkyl, carboxy-C3-C10-cycloalkyl, carboxy- C2-C10-alkenyl, C1-C10-alkoxy, acetylacetonate, trifluoroacetlyacetonate or hexafluoroacetylacetonate, with N-heterocyclic compounds of general structure I; or with N-heterocyclic compounds of general structure II; or with N-heterocyclic compounds of general structure III.