CAS: 2107-76-8; 5,7-Dihydroxy-4-Methyl-2H-Chromen-2-One

该化合物是具有分析化学应用的多用途有机化合物,具有很强的荧光特性,适合在各种生物和环境实验中进行敏感检测和量化,其结构特征,包括二氢氧和甲基组,有助于其稳定性和反应性,促进其在复杂反应和实验中的使用.

结构式图片

物理性质

MSDS等安全信息

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号108-73-6 间苯三酚 | CAS号105-45-3 乙酰乙酸甲酯 | CAS号141-97-9 乙酰乙酸乙酯 | CAS号4341-76-8 2-丁炔酸乙酯 | CAS号5394-63-8 2,2,6-三甲基-4H-1,... | CAS号108-46-3 间苯二酚 | CAS号4525-25-1 methyl (Z)-3-hy... | CAS号3067-10-5 5-Methoxy-7-hyd... | CAS号2732-18-5 5,7-二羟基香豆素 | CAS号67-68-5 二甲基亚砜 | CAS号121782-76-1 5,7-diethoxy-4-... | CAS号66262-50-8 6-acetyl-5,7-di... | CAS号66695-26-9 6,8-diacetyl-5,... | CAS号66695-25-8 (5-acetyloxy-4-... | CAS号87131-34-8 5,7-dimethoxy-2... | CAS号18103-21-4 4-methyl-5,7-bi... | CAS号62113-96-6 (4-methyl-5-met...

合成工艺路线路线简述

    📜间苯三酚置于polyaniline-Sulfate Salt Catalyst Powder 乙酰乙酸乙酯体系中,用 甲苯 用作溶剂,化学反应 24.0H,以55%的收率获得5,7-二羟基-4-甲基香豆素
    参考文献:Process For Preparing Substituted Coumarins
    标题:Process For Preparing Substituted Coumarins
    摘要:本发明涉及一种制备取代香豆素的方法.更具体地,本发明涉及一种利用聚苯胺盐作为催化剂制备取代香豆素的方法.

    海关参考信息

    专利信息


    专利号:US-6313320-B1
    优先权日:1999-04-26
    标 题:Process for the preparation of calanolide precursors
    发明人：FOX MARTIN EDWARD; MEEK GRAHAM ANDREW
    权利人:CHIROTECH TECHNOLOGY INC
    摘要:The present invention concerns compounds of the formulawherein R1, R2, R3, R4 and R6 each represent H or an organic group of up to 20 C atoms, or any pair of R2 and R3 or R2 and R6 or R4 and R6 forms a cyclic group, and R5SO2 is a cleavable protecting group in which R5 is an organic group of up to 20 C atoms. These compounds are useful as intermediates in the synthesis of calanolide A and related antiviral compounds.

    专利号:JP-2007063193-A
    优先权日:2005-08-31
    标题 :Inhibitor of hyaluronic acid synthesis

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    主要参考文献


    1: Kabeya LM, Fuzissaki CN, Andrade MF, Azzolini AE, Taleb-Contini SH, Vermelho RB, Lopes JL, Lucisano-Valim YM. 4-methylcoumarin derivatives inhibit human neutrophil oxidative metabolism and elastase activity. J Med Food. 2013 Aug;16(8):692-700. doi: 10.1089/jmf.2012.0184. Epub 2013 Aug 1.
    2: Macáková K, Řeháková Z, Mladěnka P, Karlíčková J, Filipský T, Říha M, Prasad AK, Parmar VS, Jahodář L, Pávek P, Hrdina R, Saso L. In vitro platelet antiaggregatory properties of 4-methylcoumarins. Biochimie. 2012 Dec;94(12):2681-6. doi: 10.1016/j.biochi.2012.09.006. Epub 2012 Sep 17. 67(5):467-71. 92(9):1089-100. doi: 10.1016/j.biochi.2010.06.012. Epub 2010 Jun 19. 113(25):8599-606. doi: 10.1021/jp9010058. 54(10):3521-7. doi: 10.1021/jf053071w. 33(2):67-81. doi: 10.1016/j.bioorg.2004.12.001. 19(4):647-8. doi: 10.2116/analsci.19.647. 27(4):713-22. doi: 10.1016/0306-3623(95)02112-4. 42(1-2):44-9. doi: 10.1007/BF02014299. 44(2):205-14. doi: 10.1016/0006-2952(92)90002-z. 21(3):141-7. doi: 10.1111/j.1600-0536.1989.tb04726.x.

    合成参考文献


    摘要:Cheng, B.; Wang, T., Science of Synthesis Knowledge Updates, (2020) 3, 180.
    摘要:Cheng, B.; Wang, T., Science of Synthesis Knowledge Updates, (2020) 3, 187.
    摘要:Cheng, B.; Wang, T., Science of Synthesis Knowledge Updates, (2020) 3, 181.
    摘要:Cheng, B.; Wang, T., Science of Synthesis Knowledge Updates, (2020) 3, 183.
    摘要:Cheng, B.; Wang, T., Science of Synthesis Knowledge Updates, (2020) 3, 184.
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