CAS: 209919-30-2; 4-Chloro-2-Methylphenylboronic Acid

上下游产品

CAS号14495-51-3 2-溴-5-氯甲苯 | CAS号95-69-2 4-氯-2-甲基苯胺 | CAS号1570-64-5 4-氯-2-甲基苯酚 | CAS号916220-05-8 间(2-甲基-4-氯苯基)苯甲酸

2-溴-5-氯甲苯置于正丁基锂,硼酸三异丙酯,盐酸体系中,用 四氢呋喃,正己烷,水 用作溶剂,化学反应 2.0H,以81%的收率获得4-氯-2-甲基苯硼酸
参考文献: Pharmaceutical Composition For Preventing And Treating Metabolic Bone Diseases Containing Alpha-Arylmethoxyacrylate Derivatives[fr] Composition Pharmaceutique Destinee A Prevenir Et A Traiter Des Maladies Osseuses Metaboliques,Contenant Des Derives D'Alpha-Arylmethoxyacrylate
标题: Pharmaceutical Composition For Preventing And Treating Metabolic Bone Diseases Containing Alpha-Arylmethoxyacrylate Derivatives[fr] Composition Pharmaceutique Destinee A Prevenir Et A Traiter Des Maladies Osseuses Metaboliques,Contenant Des Derives D'Alpha-Arylmethoxyacrylate
摘要:本发明涉及使用特定的α-芳基甲氧基丙烯酸酯衍生物,或其药理学上可接受的盐或溶剂,用于预防和治疗代谢性骨疾病.

专利信息

专利号:US-2006089405-A1
优先权日:2004-10-21
标 题 :Asymmetric synthesis of dihydrobenzofuran derivatives
发明人：ZHOU DAHUI; STACK GARY P; GONTCHAROV ALEXANDER V
权利人:WYETH CORP
摘要:This invention concerns a process for the preparation of benzofuran derivatives. In some aspects, these compounds are of formula I: n n nwherein each of R 1 , R 2 , R 3 , and R 4 is as defined herein.

专利号:US-12428425-B2
优先权日:2020-05-04
标 题:Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use
发明人：CZABANIUK LARA C; HOPPER TIMOTHY; HOUZE JONATHAN B; PANTELEEV JANE; RESCOURIO GWENAELLA; SANTORA VINCENT; WANG HAOXUAN; WHITE RYAN D; WONG ALICE R; WU YONGWEI; BOS MAXENCE; MANCUSO JOHN; FRANZONI IVAN
权利人:AMGEN INC; VIGIL NEUROSCIENCE INC
摘要:The present disclosure provides compounds of Formula I, useful for the activation of Triggering Receptor Expressed on Myeloid Cells 2 (“TREM2â€?).This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a neurodegenerative disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.

专利号:AU-2005299757-A1
优先权日:2004-10-21
标 题:Asymmetric synthesis of dihydrobenzofuran derivatives

专利号:CA-2584775-A1
优先权日:2004-10-21
标题:Asymmetric synthesis of dihydrobenzofuran derivatives

专利号:US-8383643-B2
优先权日:2009-07-28
标题 :Spiro compounds useful as inhibitors of stearoyl-coenzyme A delta-9 desaturase
发明人：LECLERC JEAN-PHILIPPE; LI CHUN-SING; MORADEI OSCAR MIGUEL
权利人:MERCK CANADA INC; LECLERC JEAN-PHILIPPE; LI CHUN-SING; MORADEI OSCAR MIGUEL
摘要:Heteroaromatic compounds of structural formula (I) are selective inhibitors of stearoyl-coenzyme A delta-9 desaturase (SCD1) relative to other known stearoyl-coenzyme A desaturases. The compounds of the present invention are useful for the prevention and treatment of conditions related to abnormal lipid synthesis and metabolism, including cardiovascular disease, such as atherosclerosis; obesity; diabetes; neurological disease; metabolic syndrome; insulin resistance; and liver steatosis.

专利号:WO-2006047288-A2
优先权日:2004-10-21
标 题:Asymmetric synthesis of dihydrobenzofuran derivatives