CAS: 19999-87-2; Bis(Tricyclohexylphosphine)Nickel(Ii) Chloride

Nickel Dichloride,三环己基膦 以 乙醇 用作溶剂,化学反应 1.5H,以83.6%的收率获得二氯化双(三环己基膦)镍(II)
参考文献:一种催化剂及其在合成芳香氟化合物中的应用
标题:一种催化剂及其在合成芳香氟化合物中的应用
摘要:本发明属于催化剂制备及应用领域,具体涉及一种催化剂及其在合成芳香氟化合物的应用.镍催化剂为二氯‑二‑(三‑环己基膦)合镍,其分子式为ni(Pcy3)2Cl2.所述镍催化剂在催化无机氟化物取代芳香氯化物合成氟化物中的应用.本发明所用试剂易得,催化剂合成简单,操作条件简便,反应温度低,反应收率高,用时少.

专利信息

专利号:US-9994567-B2
优先权日:2015-05-22
标 题:Synthesis of heterocyclic compounds
发明人：IBRAHIM PRABHA N; LIN JACK; SPEVAK WAYNE; ZHANG JIAZHONG
权利人:PLEXXIKON INC
摘要:Provided herein are intermediates and processes useful for facile synthesis of compounds of formula (I): n nor a pharmaceutically acceptable salt, a solvate, a tautomer, an isomer or a deuterated analog thereof, wherein Q, P 1 and P 2 are as defined in this disclosure.

专利号:US-9695169-B2
优先权日:2012-05-31
标 题:Synthesis of heterocyclic compounds
发明人：IBRAHIM PRABHA N
权利人:PLEXXIKON INC
摘要:Provided herein are intermediates and processes useful for facile synthesis of biologically active molecules.

专利号:US-2023416243-A1
优先权日:2020-11-06
标 题 :Process for Preparing Heterocyclic Methanone Compounds and AZA-Bicyclo Intermediates Thereof
发明人：GRUGEL CHRISTIAN
权利人:ACTINOGEN MEDICAL LTD
摘要:The present disclosure relates to a process for synthesis of heterocyclic methanone compounds, and in particular 3′-substituted, 3-hydroxyl-(8-aza-bicyclo[3.2.1]oct-8-yl)-[5-(1h-pyrazol-4-yl)-thiophen-3-yl]-methanone compounds, and aza-bicyclo intermediates thereof. In particular, the present disclosure also relates to a process for the synthesis of Xanamem. The present disclosure also relates to a process for the synthesis of optionally protected aza-bicyclo intermediate compounds. The present disclosure also relates to 3′-substituted, 3-hydroxyl-(8-aza-bicyclo[3.2.1]oct-8-yl)-[5-(1h-pyrazol-4-yl)-thiophen-3-yl]-methanone compounds and aza-bicyclo intermediate compounds thereof.

专利号:US-2018002332-A1
优先权日:2015-05-22
标题 :Synthesis of heterocyclic compounds

专利号:EP-3298012-B1
优先权日:2015-05-22
标题:Synthesis of heterocyclic compounds

专利号:CA-2874555-A1
优先权日:2012-05-31
标 题:Synthesis of pyrrolo [2, 3 - b] pyridines