CAS: 18437-57-5; N,N-Dimethylpyridin-3-Amine

该化合物是丙烯的三级衍生物,其特点是3级二甲基氨替代物.该化合物是有机合成的多用途中间体,特别是在制药,农用化学品和协调综合体的准备方面.其二甲基氨基电饱和组增强了核分裂和催化过程的再活性,使其对构建热循环框架很有价值.该化合物在普通有机溶剂中表现出良好的溶解性,促进了其在同质反应系统中的使用.在标准条件下,其稳定性确保了可靠的处理和储存. N,N-Dimephypypridrin-3-胺也用于金属过渡催化设计,因为其中度基本性和不完全性.

结构式图片

相似化合物

18364-47-1 39856-52-5 39856-56-9

欧盟法规

C&L通报

上下游产品

pyridin-3-ylamine methanol formaldehyd 3-Chloropyridine3-dimethylamino-1-(2,4-dinitro-phenyl)-pyridinium; chloride 2,6-dibromo-3-dimethylaminopyridine pyridine 3-Chloropyridine

合成工艺路线路线简述

    📜3-氨基吡啶 以70%的收率获得
    参考文献:Giam C. S.; Hauck A. E.,Org. Prep. And Proced. Int.,1977,No 9,9-11
    标题:Giam C. S.; Hauck A. E.,Org. Prep. And Proced. Int.,1977,No 9,9-11

    海关参考信息

    专利信息


    专利号:JP-2014523890-A
    优先权日:2011-06-30
    标题:Novel precursors for the direct synthesis of 18F-fluoromethoxy compounds for PET imaging and the direct radioactive synthesis of protected derivatives of O-([18F] fluoromethyl) tyrosine

    专利号:US-2004053999-A1
    优先权日:1997-09-17
    标题 :Novel compounds and methods for synthesis and therapy
    发明人:BISCHOFBERGER NORBERT W; DAHL TERRENCE C; HITCHCOCK MICHAEL J M; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; MILLS ROGER G; WILLIAMS MATTHEW A
    摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.

    专利号:US-6225341-B1
    优先权日:1995-02-27
    标 题:Compounds and methods for synthesis and therapy
    发明人:BISCHOFBERGER NORBERT W; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; WILLIAMS MATTHEW A
    权利人:GILEAD SCIENCES INC
    摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.

    专利号:US-10995078-B2
    优先权日:2013-03-13
    标 题:Compounds and compositions for inhibition of FASN
    发明人:BAIR KENNETH W; LANCIA JR DAVID R; LI HONGBIN; LOCH JAMES; LU WEI; MARTIN MATTHEW W; MILLAN DAVID S; SCHILLER SHAWN E R; TEBBE MARK J
    权利人:FORMA THERAPEUTICS INC
    摘要:The present invention relates to compounds and composition for inhibition of FASN, their synthesis, applications, and antidotes. An illustrative compound of the invention is shown below:

    专利号:US-5639852-A
    优先权日:1994-09-01
    标 题:Immunostimulatory agents
    发明人:RICH DANIEL H; MALKOVSKY MIROSLAV; ANGELL YVONNE M
    权利人:WISCONSIN ALUMNI RES FOUND
    摘要:Compositions and methods are described for the synthesis of novel analogs of cyclosporin A, and the use of those analogs as immunostimulatory agents.

    专利号:US-6710198-B2
    优先权日:1998-01-15
    标题 :Perfluoro-n-alkylsulfonic acid derivatives
    发明人:WACHTLER ANDREAS; DERWENSKUS KARL-HEINZ; MEUDT ANDREAS
    权利人:MERCK PATENT GMBH
    摘要:Described are bis(perfluoro-n-alkane-sulfonate) compounds, methods for preparing these compounds and use of these compounds, for example as starting materials for the synthesis of chiral and phosphine ligands for transition metal catalysts.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:F. Cruège, G. Girault, S. Coustal, J. Lascombe and P. Rumpf. Bull. Soc. Chim. France 1970, 3889.
    参考文献:10.1007/s00894-002-0075-z
    摘要:Hennemann M, Clark T. A QSPR-Approach to the Estimation of the p K HB of Six-Membered Nitrogen-Heterocycles using Quantum Mechanically Derived Descriptors. Journal of Molecular Modeling. 2002 Apr 01;8(4):95–101. doi: 10.1007/s00894-002-0075-z.
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知