CAS: 179923-32-1; (2,3,4,5-Tetrafluorophenyl)Boronic Acid

📜四氟苯置于正丁基锂,硼酸三异丙酯,盐酸体系中,用 乙醚,正己烷 用作溶剂,化学反应生成2,3,4,5-四氟苯硼酸
参考文献:(Fluoroorgano)Fluoroboranes And-Fluoroborates I: Synthesis And Spectroscopic Characterization Of Potassium Fluoroaryltrifluoroborates And Fluoroaryldifluoroboranes
标题:(Fluoroorgano)Fluoroboranes And-Fluoroborates I: Synthesis And Spectroscopic Characterization Of Potassium Fluoroaryltrifluoroborates And Fluoroaryldifluoroboranes
摘要:A Convenient Preparation Of K[arbf3] (Ar= 2-C6H4F,3-C6H4F,4-C6H4F,2,6-C6H3F2,3,5-C6H3F2,2,4,6-C6H2F3,3,4,5-C6H2F3,2,3,4,5-C6Hf4 And C6F5) Is Offered And The Ir And Multinuclear NMR Spectra Of These Salts Are Reported. Treatment Of The Trifluoroborate Salts With Bf3 In Chlorocarbon Solvents Provides An Easy Synthetic Route To The Corresponding Aryldifluoroboranes Arbf2. The Multinuclear NMR Spectra Of Arbf2 Are Presented. The Electron Substituent Effect Of The [-Bf3](-)-Group Shows This Substituent As One Of The Strongest Sigma-Electron Donors,While Its Pi-Electron Influence Is Negligible (Sigma(I) =-0.32,Sigma(R) =-0.07). (C) 2000 Elsevier Science S.A. All Rights Reserved.
Doi:10.1016/s0022-328X(99)00690-7

专利信息

专利号:US-11225655-B2
优先权日:2010-04-16
标题:Bi-functional complexes and methods for making and using such complexes
发明人：GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK
权利人:GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK; NUEVOLUTION AS
摘要:The present invention is directed to a method for the synthesis of a bi-functional complex comprising a molecule part and an identifier oligonucleotide part identifying the molecule part. A part of the synthesis method according to the present invention is preferably conducted in one or more organic solvents when a nascent bi-functional complex comprising an optionally protected tag or oligonucleotide identifier is linked to a solid support, and another part of the synthesis method is preferably conducted under conditions suitable for enzymatic addition of an oligonucleotide tag to a nascent bi-functional complex in solution.

专利号:WO-2025006693-A1
优先权日:2023-06-30
标 题 :Cannabidiol-like compounds and methods for the selective preparation of the same
发明人：CHITTIBOYINA AMAR G; CHATTERJEE SHAMBA; PANDEY PANKAJ; KHAN IKHLAS A
权利人:UNIV MISSISSIPPI
摘要:In one aspect, the disclosure relates to new cannabidiol (CBD) analogs produced from allylic monoterpene alcohols and substituted resorcinols in the presence of aryl boronic acids, efficient and mild synthetic methods of making the new CBD analogs, and improved methods of making known CBD analogs. In one aspect, the methods produce low amounts of tetrahydrocannabinol (THC)-like compounds, low amounts of abnormal cannabidiol (abn-CBD) analogs, and higher amounts of CBD analogs, greatly simplifying purification. The methods can be tailored further to produce low amounts of CBD analogs and higher amounts abn-CBD analogs. In the disclosed methods, synthesis parameters can be varied in order to selectively produce a desired normal or abnormal regioisomer.