专利号:US-9957355-B2 优先权日:2013-06-12 标 题 :Device and method for synthesis of a polymer under separation of a gaseous substance 发明人:ZHU NING; STAMMER ACHIM; CLAUSS JOACHIM; KORY GAD 权利人:BASF SE 摘要:The invention relates to a device for synthesis of a polymer under separation of a gaseous substance. Said device comprises a reaction chamber ( 1 ), which has a top section ( 11 ), a middle section ( 12 ) and a bottom section ( 13 ), an inlet opening ( 2 ) which is arranged in the middle section ( 12 ), a first outlet opening ( 3 ) which is arranged in the bottom section ( 13 ), a second outlet opening ( 4 ) which is arranged in the top section ( 11 ), a first return opening ( 51 ), which is arranged in the bottom section ( 13 ), a second outlet opening ( 52 ), which is arranged under the top section ( 11 ), a distribution device ( 6 ), which is arranged between the top section ( 11 ) and the middle section ( 12 ), and a removal device ( 7 ) which is arranged to be movable along the top section ( 11 ). The invention further relates to a method for synthesis of a polymer which can be carried out in said device.
专利号:US-9631051-B2 优先权日:2013-06-12 标 题:Device for the synthesis of a polymer with extraction of a gaseous substance comprising a reaction chamber having at least one circular-cylindrical section 发明人:ZHU NING; STAMMER ACHIM; CLAUSS JOACHIM; KORY GAD 权利人:BASF SE 摘要:An apparatus for synthesis of a polymer with separation of a gaseous substance comprises a reaction space having an essentially circular cylindrical upper section which is bounded by two circular faces and one shell face and has a longitudinal cylinder axis, and a lower section, an inlet orifice disposed in a circular face or the shell face of the upper section, a first outlet orifice disposed in a wall of the lower section, a second outlet orifice disposed in the shell face of the upper section opposite the first outlet orifice, and a removal device which is disposed so as to be rotatable about the longitudinal cylinder axis and is in contact with both circular faces and the shell face. This apparatus can especially be used for performance of a process including the feeding of an oligomer melt into a reaction space through an inlet orifice, the polymerization of the oligomer melt to give a polymer melt, the removal of the polymer melt from the reaction space through a first outlet orifice of the reaction space, and the removal of a gaseous substance from the reaction space through a second outlet orifice of the reaction space, wherein deposits on at least one inner wall of the reaction space are removed by a removal device and transported into the oligomer melt.
专利号:WO-2014087110-A1 优先权日:2012-12-07 标 题:Method for synthesising an addition salt with a pharmaceutically acceptable acid of 4-{3-[cis-hexahydrocyclopenta[c]pyrrol-2(1h)-yl]propoxy}benzamide, and the associated crystalline forms 发明人:PIERRY CAMILLE; ROBERT NICOLAS; LECOUVE JEAN-PIERRE; LETELLIER PHILIPPE 权利人:SERVIER LAB 摘要:A method for the industrial synthesis of an addition salt with a pharmaceutically acceptable acid of 4-{3-[ cis -hexahydrocyclopenta[ c ]pyrrol-2(1 H )-yl]propoxy}benzamide of formula (I), in which ΗΧ represents a pharmaceutically acceptable acid, and the associated crystalline forms. Drugs
专利号:US-8183409-B2 优先权日:2004-05-06 标题:High yield and rapid synthesis methods for producing metallo-organic salts 发明人:CHRISTGAU STEPHAN; ANDERSEN JENS E T 权利人:CHRISTGAU STEPHAN; ANDERSEN JENS E T; OSTEOLOGIX AS 摘要:A new method for preparing salts of metal cations and organic acids, especially divalent salts of alkaline earth metal ions from group II of the periodic system and carboxylic acids. The method comprising the use of a high temperature (about 90° or more) and, optionally. high pressure, in order to obtain a higher yield, purity and faster reaction speed than obtained with known synthesis methods. In particular, the present invention relates to the production of strontium salts of carboxylic acids. Novel strontium salts are also provided by the present method.
专利号:US-7560252-B2 优先权日:2002-12-27 标 题 :Borrelidin-producing polyketide synthase and its use 发明人:SALAS JOSE A; MENDEZ CARMEN; OLANO CARLOS; SANCHEZ CESAR; BRANA ALFREDO F; WILKINSON BARRIE; MARTIN CHRISTINE J; MOSS STEVEN; LEADLAY PETER F; OLIYNYK MARKO 权利人:BIOTICA TECH LTD; UNIV OVIEDO 摘要:The present invention relates to the biosynthesis of polyketides and derives from the cloning of nucleic acids encoding a polyketide synthase and other associated proteins involved in the synthesis of the polyketide borrelidin. Materials and methods including enzyme systems, nucleic acids, vectors and cells are provided for the preparation of polyketides including borrelidin and analogues and derivatives thereof. Novel polyketide molecules are also provided.
专利号:US-2009137678-A1 优先权日:2005-07-06 标 题:High yield synthesis methods for producing organic salts of strontium 发明人:CHRISTGAU STEPHAN; ANDERSEN JENS E T 权利人:CHRISTGAU STEPHAN; ANDERSEN JENS E T 摘要:New organic salts of strontium and methods of synthesizing such salts with high purity, high yields and with short processing times, at neutral conditions and at low reaction temperature, such as a temperature at or below 50° C.