2,4-二甲基-3-戊酮置于trans-Rucl(6,6'-Dihydroxyterpyridine)(Pph3)2Pf6,Potassium Tert-Butylate,异丙醇体系中,化学反应 12.0H,以17%的收率获得产物2,4-二甲基-3-戊醇 参考文献:6,6'-Dihydroxy Terpyridine: A Proton-Responsive Bifunctional Ligand And Its Application In Catalytic Transfer Hydrogenation Of Ketones 标题:6,6'-Dihydroxy Terpyridine: A Proton-Responsive Bifunctional Ligand And Its Application In Catalytic Transfer Hydrogenation Of Ketones 摘要:配体6,6'-二羟基三吡啶(dhtp)被介绍为一种双功能配体,能够指导与金属配位底物间的质子传递事件.对ru(II)-Dhtp配合物的固态分析揭示了dhtp羟基与ru结合的氯配体之间的定向氢键相互作用.通过酮的选择性转移氢化反应,展示了dhtp的实用性. DOI:10.1039/c2Cc36927C
专利号:US-7314960-B1 优先权日:2006-09-28 标 题:Catalytic synthesis of oxygenate from alcohol 发明人:LIN SHENG-DIANN; HSIAO TING-CHOU 权利人:UNIV YUAN ZE 摘要:The present invention discloses a method for catalytic synthesis of oxygenate from alcohol. At first, a feeding material comprising at least one alcohol is provided. Next, a copper-containing catalyst is provided and the catalyst further comprises at least one metal element selected from the group consisting of the following: zinc, magnesium, and aluminum elements. Following that, a catalytic reaction of the feeding material over the copper-containing catalyst is carried out to synthesize at least one oxygenate.
专利号:US-9409945-B2 优先权日:1999-10-04 标 题 :Combinatorial synthesis of libraries of macrocyclic compounds useful in drug discovery 发明人:DESLONGCHAMPS PIERRE; DORY YVES; BERTHIAUME GILLES; OUELLET LUC; LAN RUOXI 权利人:OCERA THERAPEUTICS INC 摘要:A library of macrocyclic compounds of the formula (I) n n n n n n n n n n n n where part (A) is a n n n n n n n n n n n n n n n n  bivalent radical, a —(CH 2 ) y — bivalent radical or a covalent bond; n where part (B) is a n n n n n n n n n n n n n n n n  bivalent radical, a —(CH 2 ) z — bivalent radical, or a covalent bond; n where part (C) is a n n n n n n n n n n n n n n n n  bivalent radical, a —(CH 2 ) t — bivalent radical, or a covalent bond; and n where part (T) is a —Y-L-Z— radical wherein Y is CH 2 or CO, Z is NH or O and L is a bivalent radical. These compounds are useful for carrying out screening assays or as intermediates for the synthesis of other compounds of pharmaceutical interest. A process for the preparation of these compounds in a combinatorial manner, is also disclosed.
专利号:WO-9526975-A1 优先权日:1994-03-30 标题 :Acyclic aliphatic branched alkyl groups as constituents of protective groups bound to side chains of amino-acid moieties, and their use in the preparation of peptide, polypeptide or protein structures 发明人:UNDEN ANDERS 权利人:UNDEN ANDERS 摘要:A protective group bound to a side chain of an amino-acid moiety, which group is an aliphatic acyclic branched alkyl group protecting a thiol, hydroxyl, or carboxyl group or an aliphatic acyclic branched alkoxycarbonyl group protecting an amino group or heterocyclic nitrogen, wherein the alkyl and alkoxy entities have from 6 to 18 carbon atoms and have at least two identical alkyl chains, is described. Further, the use of such a protective group bound to a side chain of an amino-acid moiety in the synthesis of peptides, polypeptides and proteins is disclosed.
专利号:US-5753726-A 优先权日:1995-12-20 标 题:Synthesis of modified epoxy resins for cathodic electrodeposition with catalyst deactivation and diol modification 发明人:REUTER HARDY; JOUCK WALTER; OTT GUENTHER 权利人:BASF LACKE & FARBEN 摘要:Epoxy resins for preparing water-dispersible binders for cathodic electrodeposition coating materials, the epoxy resin being preparable by reacting a) polyepoxides having at least one glycidyl group per molecule b) and, optionally, up to 60% by weight, based on the overall epoxy resin reaction product, of aliphatic and/or alicyclic hydroxy compounds having preferably two or on average less than two hydroxyl groups per molecule and a molecular weight of less than 9000 g/mol, c) in the presence of a catalyst consisting of neutral metal salts, such as alkali metal salts and alkaline earth metal salts, zinc salts and nickel salts of tetrafluoroboric, tetrachloroboric, hexafluoro- antimonic,hexachloroantimonic,hexafluorophosphoric, perchlorate and periodic acid, and d) adding a deactivating agent which prevents the epoxy groups reacting further or effectively reduces the rate of such reaction as soon as the phenolic hydroxyl groups have already substantially reacted and at least 0.6% by weight of epoxy groups are still present, based on the overall weight of the epoxy resin reaction product.\\!
专利号:US-9709891-B2 优先权日:2005-12-09 标 题:Positive resist composition, resin used for the positive resist composition, compound used for synthesis of the resin and pattern forming method using the positive resist composition 发明人:KANDA HIROMI; KANNA SHINICHI 权利人:FUJIFILM CORP 摘要:A positive resist composition comprises: (A) a resin of which solubility in an alkali developer increases under an action of an acid; (B) a compound capable of generating an acid upon irradiation with actinic rays or radiation; (C) a resin having at least one of a fluorine atom and a silicon atom; and (D) a solvent; and a pattern forming method using the positive resist composition.
专利号:US-5637757-A 优先权日:1995-04-11 标 题 :One-pot synthesis of ring-brominated benzoate compounds 发明人:HILL JOHN E; FAVSTRITSKY NICOLAI A; MAMUZIC RASTKO I; BHATTACHARYA BHABATOSH 权利人:GREAT LAKES CHEMICAL CORP 摘要:A method of preparing tetrabromobenzoate compounds from tetrabromophthalic anhydride by reacting tetrabromophthalic anhydride with alcohol in the presence of a decarboxylation catalyst. The reaction may be carried out in an excess of alcohol, or with a near stoichiometric amount of alcohol by performing the reaction in an inert solvent.
[参考文献]: Bart A C Van As, Et Al. Iterative Tandem Catalysis Of Secondary Diols And Diesters To Chiral Polyesters. Chemistry. 2007;13(29):8325-32.
合成参考文献
摘要:Kostikov, R. R.; Khlebnikov, A. F.; Sokolov, V. V., Science of Synthesis, (2010) 47, 803. 摘要:Pàmies, O., Science of Synthesis, (2022) , 278. 摘要:González-Granda, S.; Gotor-Fernández, V., Science of Synthesis, (2022) , 231. 摘要:Adriaensen, K.; De Vos, D., Science of Synthesis, (2022) , 173. 摘要:Adriaensen, K.; De Vos, D., Science of Synthesis, (2022) , 144.