CAS: 5458-48-0; 1-Cyclohexyl-4-Nitrobenzene
该化合物是有机化合物,其特征是附于硝基替代苯环的环状环状体体体环状物;该化合物一般是黄色至褐色固体,由于苯环的存在,其芳香特性为人所知;硝基化合物(-NO2)是一个强大的电子提取组,可影响化合物的反活动性和稳定性;该产品一般在水中不溶解,但在有机溶剂中可溶性,反映其疏水性;环氧和硝基物组的存在有助于其独特的化学行为,使其对各种化学合成和应用感兴趣;此外,1-氯乙烯基-4-硝基苯在实验室或工业环境中使用时,可能具有某些毒理特性,需要谨慎处理和考虑安全协议;总体而言,该化合物在有机合成中起着有用的中间作用,并可能在材料科学和药物方面产生应用.
物理性质
MSDS等安全信息
上下游产品
CAS号827-52-1 环己基苯 | CAS号100-25-4 对二硝基苯 | CAS号53535-83-4 9-cyclohexyl-9-... | CAS号110-83-8 环己烯 | CAS号542-18-7 氯代环己烷 | CAS号71-43-2 苯 | CAS号108-93-0 环己醇 | CAS号4441-56-9 环己基硼酸 | CAS号586-78-7 对溴硝基苯 | CAS号108-85-0 溴代环己烷 | CAS号29030-57-7 Acetamide,N-(4-... | CAS号636-98-6 4-硝基碘苯 | CAS号6373-50-8 4-环己苯胺 | CAS号25109-28-8 1-溴-4-环己基苯 | CAS号62-23-7 对硝基苯甲酸 | CAS号7137-56-6 Benzene, 1-cycl... | CAS号829-32-3 1-chloro-4-cycl... | CAS号62115-75-7 2-chloro-1-cycl... | CAS号62115-76-8 3-chloro-4-cycl... | CAS号62115-77-9 2-chloro-1-cycl...合成工艺路线路线简述
📜氯代环己烷置于三氯化铝体系中,化学反应生成 4-环己基-1-硝基苯
参考文献:Mayes; Turner,Journal Of The Chemical Society,1929,P. 507
标题:Mayes; Turner,Journal Of The Chemical Society,1929,P. 507
海关参考信息
- 2902600000-乙苯
2902700000-异丙基苯 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-4041111-A
优先权日:1975-03-04
标题:Phosphonate monoesters and method of preparation
发明人：KELLY SUSAN J; BUTLER LARRY G
权利人:PURDUE RESEARCH FOUNDATION
摘要:Synthesis of phosphonate monoesters, as well as the use of such monoesters as substrates for enzymes which normally hydrolyze phosphodiester linkages, and a method for distinguishing between Type I and Type II phosphodiesterase enzymes using such monoesters as substrates are disclosed herein. Monoesters of phosphonic acids are prepared by the displacement of chloride from an appropriate phosphonic acid dichloride by a phenol or alcohol with pyridine as the solvent, reacting the same and then removing the solvent, after which the remaining ester chloride and dichloride are hydrolyzed by addition of water. The acid and ester are then separated and the acid-free ester is taken up in a polar organic solvent and precipitated as a salt by the addition of aqueous base, with the product then being filtered, washed with fresh acetone, dried and then stored until needed. The thus formed phosphonate monoesters are shown to be effective for use as substrate for phosphodiesterase of the Type I specificity and are shown to be ineffective for use as substrates for phosphodiesterase of the Type II specificity. The type of phosphodiesterase is therefore determined by the amount of activity against phosphonate monoesters.
专利号:BR-PI0711208-A2
优先权日:2006-05-19
标 题 :compounds, intermediates for the synthesis of compounds, process, pharmaceutical composition, use of a compound and uses
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📌 第三方产品分析报告
合成参考文献
参考文献:10.1038/s41557-018-0156-y
摘要:Liu J, Qiu X, Huang X, Luo X, Zhang C, Wei J, Pan J, Liang Y, Zhu Y, Qin Q, Song S, Jiao N. From alkylarenes to anilines via site-directed carbon-carbon amination. Nat Chem. 2019 Jan;11(1):71–7. doi: 10.1038/s41557-018-0156-y.
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