CAS: 4091-26-3; 2-Phenylethenesulfonyl Chloride

该化合物是一种有机化合物,其特点是存在一个苯乙烯和全氟氯化物功能组,它一般是黄色液体的无色,以其反应性而著称,特别是因为二氯基苯并可以参与核生殖替代反应.这种化合物在二氯甲烷和乙醚等有机溶剂中溶解,但一般在水中溶解. -硫烯磺酰氟化物经常被用作有机合成的中间体,特别是在制作磺酰胺衍生物和其他含磺酰氟化合物时.重要的是谨慎地处理这种物质,因为它可能是腐蚀性的,并可能引起皮肤,眼睛和呼吸系统受到刺激.在与这种化学品打交道时,适当的安全防范措施,包括使用个人保护设备和在通风良好的地区工作,至关重要.

结构式图片

上下游产品

styrene 2-Chlor-2-phenyl-ethansulfonylchlorid (E)-2-Phenyl-ethenesulfonic acid 4-benzyloxy-phenyl esterX N-(Styrylsulfonyl)-benzamidin 2-phenyleth-1-ene-1-sulfonamide (E)-2-Phenyl-ethenesulfonic acid m-tolyl ester

合成工艺路线路线简述

    📜(4-Phenylmethoxyphenyl) 2-Phenylethenesulfonate置于五氯化磷体系中,化学反应生成 β-苯乙烯磺酰氯
    参考文献:Vizgert,R. V.; Enya,V. I.; Tuchapskii,I. M.,Journal Of General Chemistry Of The Ussr,1986,Vol. 56,# 11,P. 2318-2322
    标题:Vizgert,R. V.; Enya,V. I.; Tuchapskii,I. M.,Journal Of General Chemistry Of The Ussr,1986,Vol. 56,# 11,P. 2318-2322

    海关参考信息

    专利信息


    专利号:US-9422244-B2
    优先权日:2010-01-29
    标 题 :Synthesis of substituted pyrazoline carboxamidine derivatives
    发明人:VAN LOEVEZIJN ARNOLD; LANGE JOSEPHUS H M; BARF GERRIT A; DEN HARTOG ARNOLD P
    权利人:VAN LOEVEZIJN ARNOLD; LANGE JOSEPHUS H M; BARF GERRIT A; DEN HARTOG ARNOLD P; ABBVIE BAHAMAS LTD
    摘要:This invention relates to organic chemistry, in particular to processes for the preparation of pyrazoline carboxamidine derivatives of formula (I), known as potent 5-HT6 antagonists. The invention also relates to novel intermediates of these compounds. wherein the symbols have the meanings given in the description.

    专利号:WO-2011092226-A1
    优先权日:2010-01-29
    标 题:Synthesis of substituted pyrazoline carboxamidine derivatives

    专利号:US-2013060041-A1
    优先权日:2010-01-29
    标题:Synthesis of substituted pyrazoline carboxamidine derivatives

    专利号:US-6936600-B2
    优先权日:1999-04-01
    标题:Sorbitol dehrydrogenase inhibitors
    发明人:CHU-MOYER MARGARET Y; MYLARI BANAVARA L; ZEMBROWSKI WILLIAM J
    权利人:PFIZER
    摘要:This invention is directed to sorbitol dehydrogenase inhibitory compounds of the formula I, n n nwherein R 1 , R 2 and R 3 are as defined in the specification. This invention is also directed to pharmaceutical compositions containing those compounds and methods of treating or preventing diabetic complications, particularly diabetic neuropathy, diabetic nephropathy, diabetic microangiopathy, diabetic macroangiopathy and diabetic cardiomyopathy by administering such compounds to a mammal suffering from diabetes and therefore at risk for developing such complications. This invention is also directed to pharmaceutical compositions comprising a combination of a compound of formula I of this invention with an aldose reductase inhibitor and to methods of treating or preventing diabetic complications therewith. This invention is also directed to pharmaceutical compositions comprising a combination of a compound of formula I of this invention with an NHE-1 inhibitor and to methods of treating cardiomyopathy and other heart-related problems therewith. This invention is also directed to certain intermediates used in the synthesis of the compounds of formula I and to processes for preparing those intermediates.

    专利号:JP-2013518080-A
    优先权日:2010-01-29
    标 题:Synthesis of substituted pyrazoline carboxyamidine derivatives.

    专利号:JP-5792195-B2
    优先权日:2010-01-29
    标题:Synthesis of substituted pyrazoline carboxyamidine derivatives.

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    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Alonso, D. A.; Nájera, C., Science of Synthesis, (2010) 45, 243.
    摘要:Kawęcki, R., Science of Synthesis Knowledge Updates, (2018) 4, 258.
    摘要:Zhang, M.; Su, W., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 3, 127.
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