CAS: 4016-14-2; Isopropyl Glycidyl Ether

该化合物是一种有机化合物,其特点是由三环环醚组成的四氧化二氮功能组,其特点是由三环醚组成的有机化合物.该化合物具有甲基乙氧组,其性能和溶解性.通常,甘基醚因其在化学反应中的多功能性而闻名,常常作为各种聚合物和树脂合成的中间体.它们表现出中度至高度的再活性,因为经过加固的过氧化环环,使其在与核素的环状反应中发挥作用.甲基乙基苯基化合物的存在会增强其缺水性特征,影响其在有机溶剂中的溶解性.此外,2-[(1-甲基乙基氧)甲基丙基]氧可造成健康和环境风险,需要小心处理,并在使用期间采取适当的安全措施.

结构式图片

相似化合物

1513867-86-1 519033-14-8 130232-98-3

欧盟法规

统一分类与标签REACH注册ECHA物质工作场所安全标识要求ECHA物质食品接触材料-禁用CMR物质C&L通报REACH预注册废弃物危险特性清单

上下游产品

CAS号6140-80-3 2-prop-2-enoxyp... | CAS号683-60-3 异丙醇钠 | CAS号106-89-8 环氧氯丙烷 | CAS号67-63-0 异丙醇 | CAS号127692-19-7 3-nitro-7-(prop... | CAS号3141-83-1 1-AMINO-3-ISOPR... | CAS号13021-54-0 2-Propanol,1,3-... | CAS号17226-43-6 1,2-Propanediol... | CAS号17226-69-6 2,2-dimethyl-4-... | CAS号89534-18-9 2-(propan-2-ylo... | CAS号53146-34-2 2-Propanol,1-me... | CAS号6140-80-3 2-prop-2-enoxyp... | CAS号39144-30-4 1-Phenoxy-3-iso... | CAS号3944-36-3 1-异丙氧基-2-丙醇

合成工艺路线路线简述

    在 正丁基锂体系中,用 乙醚 作为反应溶剂,化学反应生成 异丙基缩水甘油醚
    参考文献:Complexes Of Cyclic Polyaza Chelators With Cations Of Alkaline Earth Metals For Enhanced Biological Activity
    标题:Complexes Of Cyclic Polyaza Chelators With Cations Of Alkaline Earth Metals For Enhanced Biological Activity
    摘要:具有高亲和力和特异性的环状多氮螯合剂,当与碱土金属阳离子的络合物一起给药时,表现出生物活性的意外改善,其中以ca(II)和mg(II)的络合物最为显著,尤其是ca(II).由于这种改善,这些络合物在治疗病理条件,包括缺血和缺血再灌注损伤方面特别有效.

    海关参考信息

    专利信息


    专利号:US-8541571-B2
    优先权日:2008-03-03
    标题:Homogeneous synthesis of cellulose ethers in ionic liquids
    发明人:MOELLMANN EUGEN; HEINZE THOMAS; LIEBERT TIM; KOEHLER SARAH
    权利人:MOELLMANN EUGEN; HEINZE THOMAS; LIEBERT TIM; KOEHLER SARAH; SE TYLOSE GMBH & CO KG
    摘要:The invention is directed to a simple and new method for the homogeneous synthesis of cellulose ethers. Ionic liquids are not only used as solvent, but also as reaction media for the homogeneous etherification of cellulose. The dissolved cellulose is treated with the etherification agent in the absence of organic and/or inorganic bases and in the absence and/or in the presence of moderate amounts of water. The obtained cellulose ethers show new distributions of substitution on the polymer chain, resulting in new properties and applications.

    专利号:US-7038062-B2
    优先权日:2004-07-01
    标题:Synthesis of cyclic trithiocarbonates from epoxides
    发明人:PARKER DANE KENTON
    权利人:GOODYEAR TIRE & RUBBER
    摘要:This invention provides a low cost technique for synthesizing cyclic trithiocarbonates by a simple one step process from epoxides that can be conducted under atmospheric pressure. This synthesis can be depicted as follows: n nwherein R represents a moiety selected from the group consisting of alkyl groups and aryl groups, wherein R′ represents a moiety selected from the group consisting of alkyl groups, aryl groups, and hydrogen atoms, and wherein R″ represents a moiety selected from the group consisting of alkyl groups, aryl groups, and hydrogen atoms, wherein the R moiety and the R′ moiety can be bonded together to form a cyclic structure, with the proviso that R″ represents a hydrogen atom if R′ represents an alkyl group or an aryl group. In this process carbon disulfide and a thiocyanate salt, such as potassium thiocyanate, are reacted with the epoxide in an ionic liquid, such as 1-butyl-3-methylimidazolium hexafluorophosphate ([Bmim] PF 6 ) in the presence of water to produce the cyclic trithiocarbonate.

    专利号:WO-9967219-A1
    优先权日:1998-06-22
    标 题:Compounds for inhibiting beta-amyloid peptide release and/or its synthesis
    发明人:AUDIA JAMES E; PORTER WARREN J; THOMPSON RICHARD C; WILKIE STEPHEN C; STACK DOUGLAS R; SHI QING
    权利人:ELAN PHARM INC; LILLY CO ELI; AUDIA JAMES E; PORTER WARREN J; THOMPSON RICHARD C; WILKIE STEPHEN C; STACK DOUGLAS R; SHI QING
    摘要:Compounds of formula (I), wherein W is a cyclic group of the type (2); (3); Y is represented by the formula (II); these compounds inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

    专利号:US-6838455-B2
    优先权日:1998-06-22
    标题 :Deoxyamino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
    发明人:AUDIA JAMES E; PORTER WARREN J; THOMPSON RICHARD C; WILKIE STEPHEN C; STACK DOUGLAS R; SHI QING
    权利人:ATHENA NEUROSCIENCES INC; LILLY CO ELI
    摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

    专利号:US-10316134-B2
    优先权日:2014-09-09
    标题:Alkenyl ether polyols
    发明人:TADEN ANDREAS; LANDFESTER KATHARINA; KIRSCHBAUM STEFAN
    权利人:HENKEL AG & CO KGAA; MAX PLANCK GESELLSCHAFT
    摘要:The invention relates to a method for producing radiation-curable alkenyl ether polyols, to radiation-curable alkenyl ether polyols produced using the method according to the invention, and to the use thereof for the synthesis of radiation-interlinkable oligomers or polymers by means of polyaddition reactions or polycondensation reactions, in particular for the synthesis of radiation-curable polyesters, polyethers, polyurethanes and polyureas, particularly preferably UV-curable polyurethanes. The invention also relates to radiation-curable polyurethane polymers that are obtained by reacting at least one alkenyl ether polyol according to the invention with a polyisocyanate.

    专利号:US-2008051323-A1
    优先权日:2004-08-21
    标 题 :Chloroquine drug compositions and methods for their synthesis
    发明人:KOSAK KENNETH M
    权利人:KOSAK KENNETH M
    摘要:This invention discloses compositions of chloroquine-coupled active agents, including methods for their preparation. The prior art has shown that chloroquines given as free drug in high enough concentration, enhances the release of various agents from cellular endosomes into the cytoplasm. The purpose of these compositions is to provide a controlled amount of chloroquine at the same site where the active agent is delivered, thereby reducing the overall dosage needed. n The compositions comprise a chloroquine substance coupled to an active agent directly or through a variety of pharmaceutical carrier substances. The carrier substances include polysaccharides, synthetic polymers, proteins, micelles and other substances for carrying and releasing the chloroquine compositions in the body for therapeutic effect. The compositions can also include a biocleavable linkage for carrying and releasing active agents for therapeutic or other medical uses. The invention also discloses carrier compositions that are coupled to targeting molecules for targeting the delivery of chloroquine substances and active agents to their site of action.
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    主要参考文献

    [参考文献]: P Foureman, Et Al. Chemical Mutagenesis Testing In Drosophila. Ix. Results Of 50 Coded Compounds Tested For The National Toxicology Program. Environ Mol Mutagen. 1994;23(1):51-63.
    [参考文献]: R Zeeman, Et Al. The Kinetics Of 1,4-Butanediol Diglycidyl Ether Crosslinking Of Dermal Sheep Collagen. J Biomed Mater Res. 2000 Sep 15;51(4):541-8.
    [参考文献]: Takashi Toyao, Et Al. Design Of Zeolitic Imidazolate Framework Derived Nitrogen-Doped Nanoporous Carbons Containing Metal Species For Carbon Dioxide Fixation Reactions. Chemsuschem. 2015 Nov;8(22):3905-12.

    合成参考文献


    摘要:Braverman, S.; Cherkinsky, M., Science of Synthesis Knowledge Updates, (2014) 3, 276.
    摘要:Aitken, R. A., Science of Synthesis Knowledge Updates, (2018) 3, 317.
    摘要:Vilhelmsen, M. H., Science of Synthesis Knowledge Updates, (2014) 2, 362.
    摘要:Podlech, J., Science of Synthesis Knowledge Updates, (2019) 1, 352.
    摘要:Johnson, J. B., Science of Synthesis: Stereoselective Synthesis, (2011) 3, 781.
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