CAS: 1956-21-4; 3-(4-Pyridyl)-Dl-Alanine

该化合物是一种氨酸衍生物,其特点是在结构的3个位置上存在一种环状的,该化合物由于其氨基酸脊椎和芳香丙烯酸组,可影响其溶解性和与生物系统的互动,因此具有水文和水晶体和极地溶液的白色至白的固体,在水体和极地溶液中可溶解,因此在各种生物化学应用中有用.

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169555-95-7 205528-30-9 37535-49-2

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合成工艺路线路线简述

    📜2-Hydroxyimino-3-[4]Pyridyl-Propionic Acid置于盐酸,Tin(Ll) Chloride体系中,化学反应生成4-吡啶丙氨酸
    参考文献:Elliott Et Al.,Journal Of The Chemical Society,1948,P. 85,88
    标题:Elliott Et Al.,Journal Of The Chemical Society,1948,P. 85,88

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    专利信息


    专利号:US-9475837-B2
    优先权日:2011-12-23
    标题 :Process for the synthesis of therapeutic peptides
    发明人：HURLEY FIONN; WEGNER KATARZYNA; FOLEY PATRICK
    权利人:IPSEN MFG IRELAND LTD
    摘要:The present invention relates to a process for the large-scale synthesis of therapeutic peptides using a Sieber Amide resin, which comprises solid-phase Fmoc-chemistry.

    专利号:US-2021163451-A1
    优先权日:2018-05-16
    标题:Methods and compositions for substituted 2,5-diketopiperazine analogs
    发明人：DING YOUSONG; JIANG GUANGDE
    权利人:UNIV FLORIDA
    摘要:Thaxtomins are phytotoxic secondary metabolites produced in plant pathogenic Streptomyces strains and have received considerable interests as bioherbicides. A cell-free, biocombinatorial approach was developed to produce a thaxtomin library for herbicide development. Combination of biosynthetic enzymes led to the production of 136 substituted 2,5-diketopiperazines, thaxtomin D, thaxtomin B and thaxtomin A analogs in a single pot. Furthermore, rational engineering of TxtA allowed the synthesis of azido-containing thaxtomin analog. Selected unnatural thaxtomins demonstrated improved herbicidal activities. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

    专利号:US-2015045534-A1
    优先权日:2011-12-23
    标题:Process for the Synthesis of Therapeutic Peptides

    专利号:US-2017137489-A1
    优先权日:2011-12-23
    标题 :Process for the Synthesis of Therapeutic Peptides

    专利号:EP-3305900-A1
    优先权日:2005-12-01
    标 题 :Enzymatic encoding methods for efficient synthesis of large libraries

    专利号:EP-2794634-A1
    优先权日:2011-12-23
    标题 :Process for the synthesis of therapeutic peptides

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    合成参考文献

    参考DOI号:10.1007/s00726-010-0829-3
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