CAS: 15500-60-4; N,N-Bis(Trimethylsilyl)Formamide

上下游产品

chloro-trimethyl-silane formamide carbon dioxide 1,1,1,3,3,3-hexamethyl-disilazaneN-formylbenzamide N-Formylcarbamidsaeure-methylester -2->-6α-formamidopenicillanatebenzyl 6β-(2R)-2-3,4-bis(benzyloxycarbonyloxy)phenyl-2-(4-ethyl-2,3-dioxopiperazin-1-yl)carbonylamino-6α-formamidopenicillanate 5-aminomethylenebarbituric acid

📜二氧化碳,六甲基二硅氮烷置于苯硅烷,C14H24N4Si*hi体系中,用 氘代苯 用作溶剂,以99%的收率获得n,N-双(三甲基硅基)甲酰胺
参考文献:Nhc-亚甲硅烷基阳离子用于使用二氧化碳催化胺的n-甲酰化
标题:Nhc-亚甲硅烷基阳离子用于使用二氧化碳催化胺的n-甲酰化
摘要:这项研究描述了硅(II)配合物的使用,即nhc-亚甲硅烷基阳离子配合物[(i Me)2 Sih] I(1,I Me =:C {n(me)c(me)} 2),以在温和条件下使用co 2和phsih 3催化伯胺和仲胺的化学选择性n-甲酰化,以提供相应的甲酰胺为唯一产物(平均反应时间:4.5小时;伯胺,平均收率:95%,平均tof :8 H-1;仲胺,平均收率:98%,平均tof:17 H-1).活动1产品收率优于目前用于该催化的非过渡金属催化剂.机理研究表明,与非过渡金属催化剂相比,配合物1中的硅(II)中心通过不同的途径催化c-n键的形成.它依次激活co 2,Phsih 3和胺,这些胺通过二氢消除机理进行反应,形成甲酰胺,硅氧烷和二氢气体.
Doi:10.1021/acscatal.0C03795

专利信息

专利号:US-11952324-B2
优先权日:2017-08-04
标 题 :Amidoamine synthesis, methods to track the reaction process
发明人：KHRAMOV DIMITRI M; CHEN YIYAN; OKHRIMENKO ALBERT
权利人:MI LLC; SCHLUMBERGER TECHNOLOGY CORP
摘要:Methods may include quantifying the concentration of residual free amine and/or free carboxylic acid in a product mixture prepared from a reaction of a multireactive species and a fatty reagent; verifying that the concentration for the free amine and/or free acid in the product mixture is within an acceptable threshold for a given application; and combining the product mixture with one or more wellbore fluid components to generate the wellbore fluid. In another aspect, methods may include including reacting the multireactive species and a fatty reactant to generate a product mixture; quantifying the concentration of residual free amine and/or free carboxylic acid in the product mixture; verifying that the concentration for the free amine and/or free acid in the product mixture is within an acceptable threshold for a given application; and collecting the product mixture.