CAS: 150806-61-4; 2-((Tert-Butoxycarbonyl)(Phenyl)Amino)Acetic Acid

该化合物是一种受保护的氨基酸衍生物,具有乙氧基碳基(Boc)组和一种苯代氨基碱酸基,主要用于peptide合成和有机转化,其中Boc组是氨基胺的临时保护组,在温酸条件下能够有选择地取消保护.苯代用可增强消毒和电子调制,使其在设计专门的peptide类比或生物活性分子中具有价值.其碳盒酸功能可以进一步同化或组合反应.该化合物的特点是纯度和稳定性高,确保合成应用的可靠性能.

结构式图片

相似化合物

103-01-5 21911-75-1 40643-55-8

欧盟法规

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上下游产品

tert-butyl 4,6-dimethoxy-1,3,5-triazinyl carbonate N-Phenylglycine tert-butyl dicarbonatedi-tert-butyl dicarbonate tert-butyl allyl(phenyl)carbamate 1-amino-3-(4-iodophenoxy)propane hydr°Chloride [1(R)-[(2,3-dihydrospiro[1H-indene-1,4'-piperidin]-1'-yl)carbonyl]-1-phenylmethyl]carbamic acid 1,1-dimethylethyl ester N-(tert-butoxycarbonyl)-D-cyclohexylglycine

合成工艺路线路线简述

    📜Tert-Butyl Allyl(Phenyl)Carbamate置于ruo2/bati4O9 Sodium Periodate体系中,用 Phosphate Buffer,乙酸乙酯 用作溶剂,化学反应 21.0H,以90%的收率获得[[(1,1-二甲基乙氧基)羰基]苯基氨基]乙酸
    参考文献:Use Of The Composite Material Ruo2/bati4O9 As An Environmentally Benign Solid Catalyst For The Oxidative Cleavage Of Olefins
    标题:Use Of The Composite Material Ruo2/bati4O9 As An Environmentally Benign Solid Catalyst For The Oxidative Cleavage Of Olefins
    摘要:在乙酸乙酯-水溶液中,Ruo2/bati4O9复合材料和naio4的催化作用已被证明能够有效裂解烯烃,生成高收率的酮,醛和/或羧酸.
    Doi:10.1055/s-2007-992378

    海关参考信息

    专利信息


    专利号:US-2019276389-A1
    优先权日:2015-12-18
    标题:Synthesis of aryl cyclohexane ester derivatives useful as sensates in consumer products
    发明人:WOS JOHN AUGUST; YELM KENNETH EDWARD; BUNKE GREGORY MARK; FREDERICK HEATH ALAN; REILLY MICHAEL; HAUGHT JOHN CHRISTIAN; SREEKRISHNA KOTI TATACHAR; LIN YAKANG
    权利人:PROCTER & GAMBLE
    摘要:Personal care compositions, such as oral care and skin care compositions containing a flavor/perfume system comprising one or more coolants. The pleasant cool sensation provided by a coolant is enhanced in terms of quicker onset, greater intensity, impact or longer duration, which improves appeal and acceptability of the compositions to consumers.

    专利号:US-2005192265-A1
    优先权日:2003-03-20
    标 题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
    发明人:THOMPSON RICHARD C; WILKIE STEPHEN; STACK DOUGLAS R; VANMETER ELDON E; SHI QING; BRITTON THOMAS C; AUDIA JAMES E; REEL JON K; MABRY THOMAS E; DRESSMAN BRUCE A; CWI CYNTHIA L; HENRY STEVEN S; MCDANIEL STACEY L; STUCKY RUSSELL D; PORTER WARREN J
    摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions that include a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

    专利号:WO-9967219-A1
    优先权日:1998-06-22
    标 题:Compounds for inhibiting beta-amyloid peptide release and/or its synthesis
    发明人:AUDIA JAMES E; PORTER WARREN J; THOMPSON RICHARD C; WILKIE STEPHEN C; STACK DOUGLAS R; SHI QING
    权利人:ELAN PHARM INC; LILLY CO ELI; AUDIA JAMES E; PORTER WARREN J; THOMPSON RICHARD C; WILKIE STEPHEN C; STACK DOUGLAS R; SHI QING
    摘要:Compounds of formula (I), wherein W is a cyclic group of the type (2); (3); Y is represented by the formula (II); these compounds inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

    专利号:WO-9966934-A1
    优先权日:1998-06-22
    标 题 :CYCLIC AMINO ACID COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS
    发明人:AUDIA JAMES E; DRESSMAN BRUCE A; SHI QING
    权利人:ELAN PHARM INC; LILLY CO ELI; AUDIA JAMES E; DRESSMAN BRUCE A; SHI QING
    摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

    专利号:US-6774125-B2
    优先权日:1998-06-22
    标 题:Deoxyamino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
    发明人:AUDIA JAMES E; THOMPSON RICHARD C; WILKIE STEPHEN C; BRITTON THOMAS C; PORTER WARREN J; HUFFMAN GEORGE W; LATIMER LEE H
    权利人:ELAN PHARM INC; LILLY CO ELI
    摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

    专利号:US-6509331-B1
    优先权日:1998-06-22
    标题:Deoxyamino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
    发明人:AUDIA JAMES E; THOMPSON RICHARD C; WILKIE STEPHEN C; BRITTON THOMAS C; PORTER WARREN J; HUFFMAN GEORGE W; LATIMER LEE H
    权利人:ELAN PHARM INC; LILLY CO ELI
    摘要:Disclosed are compounds which inhibit beta-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits beta-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1007/bf01388170
    摘要:Calmes M, Daunis J. How to build optically active alpha-amino acids. Amino Acids. 1999;16(3-4):215–50. doi: 10.1007/bf01388170.
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