CAS: 102-16-9; Benzyl Phenylacetate

上下游产品

CAS号103-82-2 苯乙酸 | CAS号100-51-6 苯甲醇 | CAS号201230-82-2 carbon monoxide | CAS号103-80-0 苯乙酰氯 | CAS号101-41-7 苯乙酸甲酯 | CAS号14338-32-0 2-氯-1-甲基吡啶碘化物 | CAS号4800-58-2 1-ethyl-2-iodoq... | CAS号52693-56-8 2-bromo-1-methy... | CAS号501-53-1 氯甲酸苄酯 | CAS号108-48-5 2,6-二甲基吡啶 | CAS号4606-15-9 苯乙酸丙酯 | CAS号103-82-2 苯乙酸 | CAS号108-88-3 甲苯 | CAS号18255-05-5 benzylselanylbenzene | CAS号100-51-6 苯甲醇 | CAS号4861-85-2 苯乙酸异丙酯 | CAS号101-41-7 苯乙酸甲酯 | CAS号7782-24-3 (|S|)-(+)-2-苯丙酸 | CAS号7782-26-5 R-2-苯基丙酸 | CAS号5460-60-6 N-(2-苯基乙基)-苯乙酰胺

📜N-苄基苯乙酰胺 反应生成苯乙酸苄酯
参考文献:Fujii,T. Et Al.,Chemical And Pharmaceutical Bulletin,1960,Vol. 8,P. 266-269
标题:Fujii,T. Et Al.,Chemical And Pharmaceutical Bulletin,1960,Vol. 8,P. 266-269

专利信息

专利号:US-11926633-B2
优先权日:2018-08-31
标 题:Synthesis methods for upadacitinib and intermediate thereof
发明人：WANG PENG; LI PIXU; WEI QIANG; CHENG WEN; WU HAO
权利人:SUZHOU PENGXU PHARMATECH CO LTD
摘要:The present disclosure relates to a JAK inhibitor upadacitinib intermediate and a preparation method therefor, and to a preparation method for a JAK inhibitor upadacitinib. The upadacitinib intermediate of the present application is as shown in Formula (II) or Formula (III),wherein, R is a protective group of nitrogen atoms, and R1 is an open-chain or cyclic amine group. Compared with the prior art, the method for the synthesis of upadacitinib of the present application, significantly reduces cost, is environmentally-friendly. And the quality of the final product is well controlled.

专利号:US-8735589-B2
优先权日:2009-08-20
标题:Process for the synthesis of naratriptan
发明人：RAO DHARMARAJ RAMACHANDRA; KANKAN RAJENDRA NARAYANRAO; CHIKHALIKAR SANDIP VASANT; GHAGARE MARUTI
权利人:RAO DHARMARAJ RAMACHANDRA; KANKAN RAJENDRA NARAYANRAO; CHIKHALIKAR SANDIP VASANT; GHAGARE MARUTI; CIPLA LTD
摘要:The present invention relates to a process for preparing naratriptan or a salt thereof, the process comprising: (a) reacting a compound of formula (3) with a compound of the formula HCCR n nwherein Z is a protecting group, Y is a leaving group and R is a trialkyl silyl group, a trialkylstannyl group or a zinc (II) halide, to obtain the compound of formula (4); (b) converting the compound of formula (4) to a compound of formula (5)n n nwherein Z′ is hydrogen or a benzyl group; (c) converting the compound of formula (5) to naratriptan; and (d) optionally converting naratriptan to a salt thereof. The present invention also provides novel compounds (3) and (4) and processes for their preparation.

专利号:US-4128572-A
优先权日:1977-01-18
标题 :Process for preparing phenylacetic acid
发明人：CASSAR LUIGI; FOA MARCO
权利人:MONTEDISON SPA
摘要:This invention relates to a process for preparing phenylacetic acid. In particular, the present invention relates to a catalytic process for the synthesis of the alkaline salts of phenylacetic acid by carbonylation of benzyl halides in a diphase system in the presence of cobalt carbonyl complexes. More particularly, the present invention relates to a process for preparing alkaline salts of phenylacetic acid by reacting a benzyl halide selected from chloride and bromide with carbon monoxide in the presence of a catalyst consisting in a salt of cobalt hydrocarbonyl, characterized in that the reaction is conducted in an aqueous/organic diphase system consisting of (a) an aqueous solution of an inorganic alkaline base, and (b) the benzyl halide in an organic solvent, in the presence of a catalyst system composed by a quaternary alkylammonium salt and by a cobalt hydrocarbonyl salt, at atmospheric pressure and at a temperature ranging from 20 DEG to 70 DEG C about.

专利号:US-8969546-B2
优先权日:2010-06-24
标 题:Compounds useful in imaging and therapy
发明人：KUMAR PIYUSH; WIEBE LEONARD; MCEWAN ALEXANDER
权利人:KUMAR PIYUSH; WIEBE LEONARD; MCEWAN ALEXANDER; UNIV ALBERTA; ALBERTA HEALTH SERVICES
摘要:Provided in the following specification are precursors or synthons that are useful for the synthesis of various arabinose based chemical and radiochemical derivatives of nitroimidazole-containing azomycin arabinosides, such as radioiodinated 1-#-D-(5-deoxy-5-[I*]-iodoarabinofuranosyl)-2-nitroimidazole (*IAZA), and radiofluorinated 1-#-D-(5-deoxy-5-[18F]-iodoarabinofuranosyl)-2-nitroimidazole (18FAZA). Such compounds are useful in imaging, therapy, or radiotherapy. Further, various syntheses of said precursors/synthons and the incorporation of said precursors/synthons into kits is provided. The precursors/synthons provided herein allow for an improved and facile manufacturing process for nitroimidazole-containing azomycin arabinosides.

专利号:US-2012220778-A1
优先权日:2009-08-20
标题 :Process for the synthesis of naratriptan

专利号:US-3708529-A
优先权日:1969-07-23
标题:Process for preparing phenylacetic acid
发明人：CASSAR L; FOA M; CHIUSOLI G
权利人:MONTEDISON SPA
摘要:PROCESS FOR THE SYNTHESIS OF PHENYLACETIC ACID BY CARBONYLATION OF BENZYL CHLORIDE. THE PROCESS COMPRISES REACTING BENZYL CHLORIDE AND CARBON MONOXIDE UNDER ATMOSPHERIC PRESSURE, AT TEMPERATURES FROM 20* TO 80*C. IN A WATER-METHANOL MEDIUM CONTAINING UP TO 35% WATER, USING A CATALYST MIXTURE CONSISTING OF A COBALT SALT, IN IRON-MANGANESE ALLOY AND A SUPLPHURATED PROMOTING AGENT. CALCIUM OXIDE IS USED AS A NEUTRALIZING AGENT. THE CALCIUM SALT OBTAINED IS TREATED WITH A STRONG MINERAL ACID TO FREE THE PHENYLACETIC ACID.