CAS: 7779-65-9; Isopentyl Cinnamate

上下游产品

i-Amyl alcohol Cinnamic acid

异戊醇,肉桂酸置于硫酸体系中,用76.1 %的收率获得产物肉桂酸异戊酯
参考文献:肉桂酸衍生物对婴儿利什曼原虫的抗利什曼原虫活性
标题:肉桂酸衍生物对婴儿利什曼原虫的抗利什曼原虫活性
摘要:婴儿利什曼原虫是南美洲,地中海盆地以及西亚和中亚的内脏利什曼病 (Vl) 的病原体.受影响最严重的国家巴西在 2017 年报告了 4297 例 Vl 病例.l. Infantum 由雌性白蛉在连续吸血期间传播.没有经过验证的疫苗可以预防感染,治疗依赖于经常出现严重副作用的药物,这证明了寻找新的抗利什曼病药物的努力是合理的.肉桂酸衍生物已显示多种药理活性,包括抗寄生虫作用.因此,在本研究中,报道了肉桂酸和 34 种衍生物对婴儿乳杆菌的生物学评价.这些化合物是通过几种合成方法制备的,并通过光谱技术和高分辨率质谱法进行了表征.结果表明,化合物 32(n-(4-异丙基苄基)肉桂酰胺)是最有效的抗利什曼病药物(ic50 = 33.71 μm),选择性指数最高(si > 42.46),其次是化合物 15(胡椒基肉桂酸酯),Ic50 = 42.80 μm 和 Si > 32.86.与两性霉素 B 相比,化合物
DOI:10.3390/molecules28062844

专利信息

专利号:US-12076423-B2
优先权日:2015-12-23
标题 :Spiculisporic acid-based composition
发明人：AGNAOU REDA; MARION CATHERINE
权利人:OREAL
摘要:Composition in the form of an oil-in-water emulsion that includes at least 1% of an oil phase, and an aqueous phase. The composition includes 0.1 to 15 wt % spiculisporic acid relative to the total weight of the composition, at least one base selected from amino acids and alkanolamines in an amount suitable for forming at least a monosalt of spiculisporic acid, less than 3% glycol(s) and/or polyol(s) relative to the total weight of the composition, at least one UV filter and/or an additive selected from volatile aromatic materials such as essential oils and fragrance substances, fillers, dyeing materials such as pigments, mother-of-pearl or particles with a metallic sheen, moisturizers, anti-wrinkle or anti-age agents, peeling agents, antioxidants, active ingredients stimulating the synthesis of epidermal and/or dermal macromolecules, dermo-relaxing agents, depigmentation agents, deodorant agents and mixtures thereof.

专利号:BR-102020012831-A2
优先权日:2020-06-23
标题:PROCESS OF IMMOBILIZATION OF LIPASES IN CHITOSAN AND STARCH-BASED BIOSSUPPORT FOR ESTERS SYNTHESIS