CAS: 63394-05-8; Plafibride

该化合物是一种化学化合物,属于药品类别,具体用作抗血压剂,主要作为血管II受体的选择性敌者,在调节血压和体液平衡方面起着关键作用;该化合物的特点是能够抑制血管II的影响,从而推动血管扩张和减少血压;该化合物通常在受控剂量中管理,以有效管理高血压;其药用动力特性包括吸收,配送,代谢和排泄,这是确定其功效和安全特征的关键;与许多药物一样,潜在的副作用可能包括眩晕,疲劳或胃肠紊乱,需要在治疗期间进行仔细监测.

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MSDS等安全信息

    上下游产品

    CAS号110-91-8 吗啉 | CAS号50-00-0 甲醛 | CAS号29973-16-8 Propanamide,N-(... | CAS号5542-60-9 2-(4-氯丙氧基)-2-甲基丙酰氯 | CAS号29973-16-8 Propanamide,N-(... | CAS号882-09-7 2-(4-氯苯氧基)异丁酸

    合成工艺路线路线简述

      📜2-(4-氯丙氧基)-2-甲基丙酰氯 以 1,4-二氧六环,吡啶,水,Petroleum Ether 作为反应溶剂,化学反应 7.0H,反应生成 普拉贝脲
      参考文献:Ribalta; Artus; Salvador,Arzneimittel-Forschung/drug Research,1981,Vol. 31,# 10 A,P. 1782-1786
      标题:Ribalta; Artus; Salvador,Arzneimittel-Forschung/drug Research,1981,Vol. 31,# 10 A,P. 1782-1786

      海关参考信息

      专利信息


      专利号:US-10925977-B2
      优先权日:2006-10-05
      标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
      发明人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S
      权利人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S; CEIL POINT LLC; UNIV TEXAS
      摘要:Novel methods of synthesis of chelator-targeting ligand conjugates, compositions comprising such conjugates, and therapeutic and diagnostic applications of such conjugates are disclosed. The compositions include chelator-targeting ligand conjugates optionally chelated to one or more metal ions. Methods of synthesizing these compositions in high purity are also presented. Also disclosed are methods of imaging, treating and diagnosing disease in a subject using these novel compositions, such as methods of imaging a tumor within a subject and methods of diagnosing myocardial ischemia.

      专利号:US-2024084356-A1
      优先权日:2021-01-23
      标题 :Ribosomal rna scaffolds for protein-free and template-free synthesis of peptides
      发明人:WANG YUHONG; XU DORIS
      权利人:UNIV HOUSTON SYSTEM
      摘要:Embodiments of the present disclosure pertain to methods of synthesizing a peptide by associating at least one isolated ribosomal RNA (rRNA) fragment with a plurality of transfer RNA fragments linked to amino acids (tRNA fragments). The at least one rRNA fragment includes at least one domain that associates with the tRNA fragments. The at least one rRNA fragment catalyzes the synthesis of the peptide through peptidyl transfer of the amino acids from the tRNA fragments independently of messenger RNA (mRNA) templates. Additionally, the peptidyl transfer occurs independently of proteins. Further embodiments of the present disclosure pertain to systems for synthesizing a peptide. Such systems include the rRNA fragments of the present disclosure and optionally a plurality of tRNA fragments.

      专利号:US-10814013-B2
      优先权日:2006-10-05
      标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications

      专利号:WO-2025019943-A1
      优先权日:2023-07-24
      标题:Small molecule ice recrystallization inhibitors and methods of use thereof
      发明人:BEN ROBERT N; DIAMANTE MARCUS
      权利人:UNIV OTTAWA
      摘要:The present application provides ice recrystallization inhibitors, and methods of synthesis and use thereof. The ice recrystallization inhibitor (IRI) compounds have the structure of Formula (A) where B is an alkyl, or substituted or unsubstituted phenyl. The IRI compounds exhibit good IRI activity and are soluble in water and in buffers, such as those used in cryopreservation.

      专利号:AU-2007308022-A2
      优先权日:2006-10-05
      标题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications

      专利号:AU-2007308022-A1
      优先权日:2006-10-05
      标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications

      供应商参考报价(招募中)

      品牌试剂参考报价(招募中)

      📌 第三方产品分析报告

      ✅ COA系统入驻 | 共享模式

      主要参考文献


      1: Filip M, Păduraru I, Nechifor M, Dănilă GH, Popovici I, Filip FM, Poşircă F. Explorarea acţiuni unui derivat al acidului fibric asupra metabolismului lipidic [The action of a fibric acid derivative on lipid metabolism]. Rev Med Chir Soc Med Nat Iasi. 1989 Jul-Sep;93(3):573-6. Romanian. 92(1):127-32. Romanian. 18(3-4):153-63. 84(15):632. Spanish. 84(15):632. Spanish. 83(18):752-5. Spanish. 36(6):273-8. Spanish. 82(19):840-2. Spanish. 5(10):707-14. 5(9):613-7. 33(3):401-4. 28(6):687-95. Spanish. 78(9):380-5. Spanish. 31(10a):1852-5. 31(10a):1850-2. 31(10a):1845-9. 31(10a):1840-4. 31(10a):1835-8. 31(10a):1831-4. 31(10a):1819-30.

      合成参考文献


      摘要:Archivos de Farmacologia y Toxicologia., 4(137), 1978 []
      摘要:Arzneimittel-Forschung. Drug Research., 31(1816), 1981 []
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