CAS: 58473-74-8; (E)-3-(3-Bromophenyl)-N-Ethylacrylamide

该化合物是一种有机化合物,其特征为氨化功能组和丙胺结构,该化合物具有溴苯基组的特点,有助于其芳香特性和潜在反应力;氮原子附着的乙基组的存在增强了其亲性,这可能会影响其在有机溶剂中的溶解性;丙胺结构中的双联体引入了几何异构体,其名称为(2E)表明双重结合的具体配置;该化合物可能展示生物活动,使其对医药化学和药物开发具有兴趣;其溴基子组还能够增强其在各种化学反应中的再活动性,例如核细胞替代或联动反应.

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CAS号75-04-7 乙胺 | CAS号59114-88-4 (E)-ethyl 3-(3-...

合成工艺路线路线简述

    📜3-溴苯乙烯置于4-二甲氨基吡啶,Tetrabutylammonium Tetrafluoroborate,碘,Sodium Acetate,盐酸-N-乙基-Nˊ-(3-二甲氨基丙基)碳二亚胺体系中,用 N,N-二甲基甲酰胺,乙腈 作为反应溶剂,化学反应 11.0H,反应生成 反式-3-溴-N-乙基肉桂酰胺
    参考文献:α,β-不饱和砜的立体选择性电化学羧化
    标题:α,β-不饱和砜的立体选择性电化学羧化
    摘要:二氧化碳(Co 2)作为一种极具吸引力的c1合成子,已广泛用于有机合成中生产羧酸.在这项研究中,在无过渡金属的条件下开发了α,β-不饱和砜的立体选择性电化学羧化反应.所有肉桂酸及其衍生物均以e构型选择性地获得.此外,芳基丙炔酸酯也可以由炔基砜生产.
    DOI:10.1016/j.Cclet.2022.107956

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    专利信息


    专利号:US-2008214827-A1
    优先权日:2004-02-03
    标 题:Synthesis of Cyanoimino-Benzoimidazoles
    发明人:GOEHRING R RICHARD; WHITEHEAD JOHN; SHAO BIN
    权利人:EURO CELTIQUE SA
    摘要:Disclosed in certain embodiments is a process for synthesizing a compound of formula (V) and salts thereof.

    专利号:CA-2555219-A1
    优先权日:2004-02-03
    标 题 :Synthesis of cyanoimino-benzoimidazoles

    专利号:WO-2005075459-A1
    优先权日:2004-02-03
    标题:Synthesis of cyanoimino-benzoimidazoles

    专利号:EP-1711484-A4
    优先权日:2004-02-03
    标题:SYNTHESIS OF CYANOIMINO-BENZOIMIDAZOLES

    专利号:EP-1711484-A1
    优先权日:2004-02-03
    标 题:Synthesis of cyanoimino-benzoimidazoles

    专利号:US-2014315720-A1
    优先权日:2012-10-24
    标 题 :Polysaccharide ester microspheres and methods and articles relating thereto
    发明人:FALLON DENIS G; GARRETT THOMAS S; KIZER LAWTON E; ZAZZARA KAREN L; COMBS MICHAEL T; JOHNSON RICHARD K; DEHART GARY
    权利人:CELANESE ACETATE LLC
    摘要:A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof. Esters thereof may be organic esters (e.g., acetate and the like), inorganic esters (e.g., sulfonates and the like), or combinations thereof. Further, the solids conent of the polysaccharide ester dope, in some instances, may be greater than about 16 wt %.

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    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Danthi SJ, Liang B, Smicker O, Coupland B, Gregory J, Gefteas E, Tietz D, Klodnitsky H, Randall K, Belanger A, Kuntzweiler TA. Identification and Characterization of Inhibitors of a Neutral Amino Acid Transporter, SLC6A19, Using Two Functional Cell-Based Assays. SLAS Discov. 2019 Feb;24(2):111-120. doi: 10.1177/2472555218794627. Epub 2018 Dec 27. Review. Italian.

    合成参考文献


    参考文献:10.2165/00003495-199448040-00002
    摘要:Pledger GW, Schmidt D. Evaluation of antiepileptic drug efficacy. A review of clinical trial design. Drugs. 1994 Oct;48(4):498–509. doi: 10.2165/00003495-199448040-00002.
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