专利号:US-2008214827-A1 优先权日:2004-02-03 标 题:Synthesis of Cyanoimino-Benzoimidazoles 发明人:GOEHRING R RICHARD; WHITEHEAD JOHN; SHAO BIN 权利人:EURO CELTIQUE SA 摘要:Disclosed in certain embodiments is a process for synthesizing a compound of formula (V) and salts thereof.
专利号:CA-2555219-A1 优先权日:2004-02-03 标 题 :Synthesis of cyanoimino-benzoimidazoles
专利号:WO-2005075459-A1 优先权日:2004-02-03 标题:Synthesis of cyanoimino-benzoimidazoles
专利号:EP-1711484-A4 优先权日:2004-02-03 标题:SYNTHESIS OF CYANOIMINO-BENZOIMIDAZOLES
专利号:EP-1711484-A1 优先权日:2004-02-03 标 题:Synthesis of cyanoimino-benzoimidazoles
专利号:US-2014315720-A1 优先权日:2012-10-24 标 题 :Polysaccharide ester microspheres and methods and articles relating thereto 发明人:FALLON DENIS G; GARRETT THOMAS S; KIZER LAWTON E; ZAZZARA KAREN L; COMBS MICHAEL T; JOHNSON RICHARD K; DEHART GARY 权利人:CELANESE ACETATE LLC 摘要:A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof. Esters thereof may be organic esters (e.g., acetate and the like), inorganic esters (e.g., sulfonates and the like), or combinations thereof. Further, the solids conent of the polysaccharide ester dope, in some instances, may be greater than about 16 wt %.
1: Danthi SJ, Liang B, Smicker O, Coupland B, Gregory J, Gefteas E, Tietz D, Klodnitsky H, Randall K, Belanger A, Kuntzweiler TA. Identification and Characterization of Inhibitors of a Neutral Amino Acid Transporter, SLC6A19, Using Two Functional Cell-Based Assays. SLAS Discov. 2019 Feb;24(2):111-120. doi: 10.1177/2472555218794627. Epub 2018 Dec 27. Review. Italian.
合成参考文献
参考文献:10.2165/00003495-199448040-00002 摘要:Pledger GW, Schmidt D. Evaluation of antiepileptic drug efficacy. A review of clinical trial design. Drugs. 1994 Oct;48(4):498–509. doi: 10.2165/00003495-199448040-00002.