CAS: 5707-04-0; Benzeneselenyl Chloride

上下游产品

chloroform diphenyl diselenide phenylselenium trichloride N-phenyldichloroselenobenzeneseleninimidoyl chlorideO,O-diethyl Se-phenyl phosphoroselenoate Selenophosphorsaeure-Se-phenyl-O,O-dipropylester 2-RS,3-RS-3-chlorobutyl-2-phenyl selenide 3-Chlor-2,3-dimethylbutyl-2-benzolselenid

📜苯硒酚置于n-氯代丁二酰亚胺体系中,用 硝基甲烷 作为反应溶剂,化学反应 0.5H,反应生成 苯基氯化硒
参考文献:通过α,β-炔的亲电子硫属/环化反应合成4-硫属酰基吡唑.
标题:通过α,β-炔的亲电子硫属/环化反应合成4-硫属酰基吡唑.
摘要:通过α,β-炔的亲电子硫属化/环化反应,已经开发出一种简便的合成4-硫磺化吡唑的方法.通过使用ncs与芳硫醇反应反应生成的亚磺酰氯或s-亲电试剂,可以诱导α,β-炔醛的环化反应.所开发的方法已成功地用于塞来昔布的亚磺酰基类似物的合成.
DOI:10.1039/d0Ob00050G

专利信息

专利号:US-6005097-A
优先权日:1996-06-14
标题 :Processes for high-yield diastereoselective synthesis of dideoxynucleosides
发明人：CHEN SHU-HUI; LI XIUYAN
权利人:VION PHARMACEUTICALS INC
摘要:The present invention relates to methods for substantially enhancing the stereoselective synthesis of β-anomeric nucleoside analogs. In methods according to the present invention, the introduction of a phenylseleno group onto a blocked lactone sugar precursor may be selected so that the desirable phenylseleno substituent is introduced on the side of the blocked lactone away from the blocking group. This stereospecific introduction of the phenylseleno group in sugar precursor allows the synthesis of nucleoside analogs and in particular, 2',3',-dideoxy- and 2',3'-dideoxy-2',3'-didehydronucleoside analogs in very high yield. In certain preferred embodiments, the preferred phenylseleno blocked lactone is obtained in an amount representing approximately 90% or more of the total amount of the stereoisomers obtained. In even more preferred embodiments, the amount of the preferred stereoisomer is at least 95%, even more preferably at least about 97% of the total amount of phenylseleno blocked lactone produced.

专利号:US-7094805-B2
优先权日:2001-12-14
标 题 :Total synthesis of merrilactone A
发明人：DANISHEFSKY SAMUEL J; BIRMAN VLADIMIR B
权利人:UNIV COLUMBIA
摘要:This invention provides a total synthesis of Merrillactone and Merrilactone analogues for use as neurotrophic agents in the treatment of neurodegenerative diseases. The invention also provides intermediates for use in the synthesis of Merrilactone and its analogues.

专利号:US-4929731-A
优先权日:1989-02-21
标题:Method for the synthesis of huperzine A and analogs thereof and compounds useful therein
发明人：KOZIKOWSKI ALAN P; XIA YAN
权利人:UNIV PITTSBURGH
摘要:The present invention relates to a method for the synthesis of certain bridged fused ring pyridines. Such bridged fused ring pyridines can be converted to huperzine A and analogs of huperzine A. The present invention also covers such bridged fused ring pyridines, compounds utilized for the preparation of the bridged fused ring pyridines and analogs of huperzine A.

专利号:US-12234203-B2
优先权日:2020-03-12
标 题:Process for the synthesis of cannabidiol and intermediates thereof
发明人：ANAND RADHIKA; SHARMA SUMIT; SINGH CHAM PANKAJ; GANNEDI VEERANJANEYULU; KUMAR MUKESH; PRATAP SINGH VARUN; PRAKASH RAHUL VISHAV; ASREY VISHWAKARMA RAM; PAL SINGH PARVINDER
权利人:COUNCIL OF SCIENT AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN OF T; COUNCIL OF SCIENT AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN OF S
摘要:The present invention relates to process for the preparation of cannabidiol (A) from the coupling of (D) and (E) through the intermediates (C) and (D) starting from compound (B). The invention further relates to the novel compounds (B), (C), (D) and (E) and reagents used in this process. More specifically, this invention provides the manufacturing of Cannabidiol (A) in milligram to gram or kilogram scale.

专利号:EP-1274680-B1
优先权日:2000-04-18
标 题 :Synthesis intermediate products for producing vitamin d derivatives
发明人：STEINMEYER ANDREAS; BOIDOL WERNER; ZORN LUDWIG
权利人:SCHERING AG
摘要:The invention relates to a new synthesis intermediate product of formula I its microbiological production and use for synthesis of vitamin D derivatives.

专利号:US-2014234364-A1
优先权日:2011-09-23
标 题:Total synthesis and immunological evaluation of saccharide moieties of the lipopolysaccharide from neisseria meningitidis
发明人：SEEBERGER PETER H; YANG YOU; ANISH CHAKKUMKAL; REINHARDT ANIKA
权利人:MAX PLANCK GES ZUR FÖRDERUNG DER WISSENSCHAFTEN E V
摘要:The present invention relates to the total chemical synthesis of the monosaccharide 35 # (R′â•?H), the disaccharide 36 # (R′≠H; R″â•?H), the trisaccharide 37 # (R′≠H; R″≠H; R′″≠H) and the tetrasaccharide 1 # (R′≠H; R″≠H; R′″≠H) of the following general formula wherein R represents —Y—NH 2 Y represents a linker R′ is H or R″ is H or R′″ is H or of the lipopolysaccharide from Neisseria meningitidis , as well as to the trisaccharide 37 # and the tetrasaccharide 1 # , to vaccines containing at least one of the saccharides 1 # , 35 # , 36 # , and 37 # and to the use of such vaccine for immunization against diseases caused by infection with bacteria containing the tetrasaccharide α-GlcNAc-(1→2)-α-Hep-( 1→3 )-α-Hep-(1→5)-α-Kdo or the trisaccharide α-Hep-(1→3)-α-Hep-(1→5)-α-Kdo or α-GlcNAc-(1→2)-±-Hep-(1→3)-α-Hep, especially for immunization against meningitis, septicaemia, pneumonia and nasopharyngitis caused by Neisseria meningitidis.