CAS: 547-25-1; (3S,4R,5R)-1,4,5,6-Tetrahydroxy-3-(((2R,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-yl)Oxy)Hexan-2-One

上下游产品

CAS号547-64-8 乳酸甲酯

📜蔗糖置于amylosucrase From Neisseria Subflava体系中,用 Aq. Buffer 作为反应溶剂,化学反应 120.0H,以51.1%的收率获得产物松二糖
参考文献:亚发奈瑟氏菌中淀粉酶的生产和表征低热量的杜兰糖和抗消化淀粉
标题:亚发奈瑟氏菌中淀粉酶的生产和表征低热量的杜兰糖和抗消化淀粉
摘要:这项研究的目的是利用来自亚氏奈瑟氏球菌(ns As)的重组淀粉酶来生产杜兰糖和抗性淀粉(rs).通过ns As处理,在40oc时,蔗糖产量最高可达到蔗糖底物的76%.为了评价土兰糖作为低热量功能性甜味剂,在连续人工消化系统中研究了其水解方式.当通过小肠阶段连续暴露兔二糖时,只有8%的二糖被水解.用ns对糊化玉米或大米淀粉进行结构改性与蔗糖一起作为糖基供体使用.酶改性淀粉的不可消化性通过支链伸长最大增加到47.3%,足以进行链链缔合和重结晶.显然,Ns As改性淀粉比天然淀粉具有更高的糊化峰值温度,并且由于长链诱导的回生作用,其糊状粘度与其消化率成反比.这些结果表明,Ns As可能是食品工业中生产下一代低热量碳水化合物食品原料的重要生物催化剂.
DOI:10.1016/j.Foodchem.2019.125225

专利信息

专利号:US-5714587-A
优先权日:1993-03-31
标 题 :Synthesis of anti-inflammatory compounds, and novel trisaccharides useful in the synthesis of anti-inflammatory compounds
发明人：LAINE ROGER A
权利人:UNIV LOUISIANA STATE; AGRICULTURAL AND MECHANICAL CO
摘要:Anti-inflammatory compounds are useful, for example, in treating arthritis and heart attack patients. Novel oligosaccharides useful in the rapid synthesis of certain anti-inflammatory compounds are disclosed, as is a rapid method of synthesizing the oligosaccharides. Low pH can loosen the acceptor specificity of galactosyltransferase (lactose synthase: EC 2.4.1.22), allowing the rapid synthesis of novel oligosaccharides. The disaccharides cellobiose (β1→4), laminaribiose (β1→3), gentiobiose (β1→6) and maltose (α1→4) acted as acceptors for lactose synthase under low pH conditions. From these four acceptors, the following four novel trisaccharides were synthesized: Gal p (β1→4)Glc p (β1→3) -Glc, Gal p (β1→4)Glc p (β1→4)-Glc, Gal p (β1→4)Glc p (β1→6)-Glc and Gal p (β1→4)Glc p (α1→4)Glc. These trisaccharides, and other oligosaccharides, may be synthesized in a few days with the disclosed technique, as opposed to the several months which would likely have been required with more traditional organic synthetic methods. These trisaccharides may be used as intermediates in the rapid synthesis of anti-inflammatory compounds.

专利号:EP-1108724-B1
优先权日:1996-01-16
标题 :Synthesis of methoxy nucleosides and enzymatic nucleic acid molecules
发明人：WINCOTT FRANCINE; BEIGELMANN LEONID; MATULIC-ADAMIC JASENKA; USMAN NASSIM; HAEBERLI PETER; KARPEISKY ALEXANDER; SWEEDLER DAVID; JARVIS THALE; DIRENZO ANTHONY
权利人:SIRNA THERAPEUTICS INC
摘要:This invention relates to chemical synthesis of 2'-O-methyl, 3'-O-methyl and 5'-O-methyl nucleosides, incorporation of novel chemical modifications in enzymatic nucleic acid molecules and improved methods for the synthesis of enzymatic nucleic acid molecules.

专利号:US-9034844-B2
优先权日:2009-04-06
标 题 :6′-sialyllactose salts and process for their synthesis and for the synthesis of other alpha-sialyloligosaccharides
发明人：TAMERLANI GIANCARLO; LOMBARDI ILARIA; BARTALUCCI DEBORA; DANESI ANDREA; SALSINI LIANA; MANONI MARCO; CIPOLLETTI GIOVANNI
权利人:TAMERLANI GIANCARLO; LOMBARDI ILARIA; BARTALUCCI DEBORA; DANESI ANDREA; SALSINI LIANA; MANONI MARCO; CIPOLLETTI GIOVANNI; INALCO SPA
摘要:The present invention relates to a process of synthesis of α-sialyl oligosaccharides and in particular of 6′-sialyllactose and its salts comprising a step of coupling by Koenigs-Knorr reaction under conditions that allow its use on an industrial scale.

专利号:US-5945529-A
优先权日:1996-07-19
标题:Synthesis of polyol fatty acid polyesters using column with inert gas stripping
发明人：CORRIGAN PATRICK JOSEPH; KENNEALLY COREY JAMES; GRANBERG ERIC PAUL
权利人:PROCTER & GAMBLE
摘要:Processes for the synthesis of polyol fatty acid polyester by transesterification of a polyol comprise reacting polyol with a first portion of fatty acid lower alkyl ester to provide a first step reaction product in which substantially all of the polyol is reacted with at least one fatty acid lower alkyl ester. The processes then employ a multistage column providing substantial plug flow of liquid therein for further transesterification of the first step reaction product. Partially esterified polyol, a second portion of fatty acid lower alkyl ester and catalyst are fed to the column to form a mixture and cause further transesterification of the partially esterified polyol and fatty acid lower alkyl ester, with lower alkyl alcohol being formed as a by product. The resulting liquid mixture of reactants and product is passed in a first direction between adjacent stages through the column for further reaction of partially esterified polyol with fatty acid lower alkyl ester. An inert stripping or sparging gas is fed through the column in a second direction between adjacent stages, counter current to the flow of the liquid mixture between adjacent stages in the first direction, with radial shear agitation. The lower alkyl alcohol by-product of the polyol-fatty acid lower alkyl ester reaction is transferred from the liquid mixture to the inert gas.

专利号:US-6620952-B1
优先权日:1999-01-28
标题:Synthesis of polyol fatty acid polyesters
发明人：CORRIGAN PATRICK JOSEPH
权利人:PROCTER & GAMBLE
摘要:Processes for the synthesis of polyol fatty acid polyester by transesterification of a polyol comprise reacting polyol with a first portion of fatty acid lower alkyl ester to provide a first step reaction product in which substantially all of the polyol is reacted with at least one fatty acid lower alkyl ester. The process then employs a multistage column for further transesterification of the first step reaction product. Partially esterified polyol, a second portion of fatty acid lower alkyl ester and catalyst are fed to the column to form a mixture and cause further transesterification of the partially esterified polyol and fatty acid lower alkyl ester, with lower alkyl alcohol being formed as a by product. The resulting liquid mixture of reactants and product is passed in a first direction between adjacent stages through the column for further reaction of partially esterified polyol with fatty acid lower alkyl ester. An inert sparging gas is fed through the column in a second direction between adjacent stages, counter current to the flow of the liquid mixture between adjacent stages in the first direction. The inert gas is directed through the liquid mixture to provide gas induce turbulence, such that the column reactor has a column ratio of at least 0.4/hour.

专利号:US-9447149-B2
优先权日:2012-03-06
标 题 :Methods and compositions for the rapid synthesis of radiometal-labeled probes
发明人：CHEN KAI; CONTI PETER STEPHEN
权利人:UNIV SOUTHERN CALIFORNIA
摘要:The present application is directed to rapid and efficient synthesis of radiometal-labeled probes, pharmaceutical compositions comprising radiometal-labeled probes, and methods of using the radiometal-labeled probes. Such radiometal-labeled probes can be used in imaging studies, such as Positron Emitting Tomography (PET) or Single Photon Emission Computed Tomography (SPECT), and therapy studies.