📜十二甲基环己硅烷置于环氧乙烷,一氧化二氮体系中,用 溶剂黄146 作为反应溶剂,化学反应 20.0H,反应生成 十二甲基环六硅氧烷 参考文献:Photolysis Of (Me2Si)6 In Argon Matrices Doped With High Concentrations (Ca. 20%) Of N2O Or C2H4O: Formation Of (Me2Sio)6 标题:Photolysis Of (Me2Si)6 In Argon Matrices Doped With High Concentrations (Ca. 20%) Of N2O Or C2H4O: Formation Of (Me2Sio)6 摘要:Irradiation Using A Low Pressure Mercury Lamp (Lambda =ca. 250 Nm) Of Argon Matrices Containing Ca. 1% (Me2Si)(6) And Ca. 20% Ethylene Oxide (C2H4O) Or Nitrous Oxide (N2O) For A Period Of Ca. 20 H Leads To The Formation Of The Cyclic Compound (Me2Sio)(6). This Has A 12-Membered Ring With Alternating Si And O Atoms. It Is Identified By Comparison Of Its Infrared Spectrum With A Spectrum Of An Authentic Sample. The Reaction Appears To Proceed By Stepwise Insertion Of O Atoms Into Si-Si Bonds. (C) 2001 Published By Elsevier Science B.V. DOI:10.1016/s0022-328X(01)01184-6
专利信息
专利号:US-2012094919-A1 优先权日:2009-03-16 标题 :Use of tripeptides 发明人:GRAEUB REMO; HEIDL MARC; IMFELD DOMINIK; MUELLER EIKE; WIKSTROEM PETER; ZIEGLER HUGO 权利人:GRAEUB REMO; HEIDL MARC; IMFELD DOMINIK; MUELLER EIKE; WIKSTROEM PETER; ZIEGLER HUGO 摘要:The present invention relates to the use of tripeptide derivatives for tightening, firming and/or moisturizing skin. Furthermore, the invention relates to a method for stimulating the synthesis of glycosaminoglycans containing a D-glucosamine and/or N-acetyl-D-glucosamine residue and/or proteoglycans by fibroblasts and/or keratinocytes such as in particular the synthesis of Hyaluronic acid and/or of the proteoglycans Decorin and/or Lumican.
专利号:EP-1721601-A1 优先权日:2005-05-11 标 题 :Use of taurine for enhancing lipid synthesis in the epidermis 发明人:DOERING THOMAS; WALDMANN-LAUE MARIANNE; WADLE ARMIN; ANDERHEGGEN BERND 权利人:HENKEL KGAA 摘要:The present invention is the use of taurine for stimulating the epidermal synthesis of barrier lipids.
专利号:US-9149659-B2 优先权日:2012-11-14 标题 :Cosmetic composition for increasing hyaluronic acid synthesis in skin and its use for repairing wrinkles 发明人:PUJOS MURIEL; BERNINI DOROTHEE; ROBERT CECILE; DOUCET OLIVIER 权利人:COTY GERMANY GMBH 摘要:The present invention relates to a skin composition which has an excellent effect on smoothing or repairing wrinkles. The composition comprises Palmitoyl Tripeptide-38 (Palmitoyl-Lysyl-Dioxymethionyl-Lysine) and Piper nigrum (Pepper) seed Extract which combination has been found to result in a synergistic effect on hyaluronan synthase 1 (HAS1) mRNA expression in human fibroblasts. The hyaluronan synthase is responsible for the synthesis of hyaluronan (hyaluronic acid) in skin. Hyaluronic acid is a constituent of the extracellular matrix of the skin and responsible for space filling, tissue repair and retention of moisture.
专利号:US-11612556-B2 优先权日:2014-12-16 标 题:Peptidic compounds, compositions comprising them and uses of said compounds, in particular cosmetic uses 发明人:PESCHARD OLIVIER; DOUCET ANNE; LEROUX RICHARD; MONDON PHILIPPE 权利人:SEDERMA SA 摘要:The peptidic compound comprises at least an aminoacid which is lysine, ornithine, diaminopropionic acid or diaminobutyric acid or a derivative of these aminoacids, on which a carboxylic acid is grafted via a peptidic bound on the nitrogen of the lateral chain, said carboxylic acid comprising a (poly)cycle or (poly)heterocycle. Preferably, the grafted carboxylic acid is an aminoacid or a derivative, in particular selected from, a proline, a hydroxyproline or pyroglutamic acid.The peptidic compound can stimulate the synthesis of the main molecules constituting the extracellular matrix of the skin, especially collagen 1 and 4 and elastin. It can be used for topical cosmetic treatment such as a global anti-aging treatment, or for specific activities, including anti-wrinkles, moisturizing, to improve the mechanical properties of the skin, firmness/tone/elasticity/flexibility, to increase density and volume of the skin, improve skin radiance, for a restructuring effect and/or to fight stretch marks.
专利号:US-12194020-B2 优先权日:2017-12-22 标 题:Reversing baldness through cannabinoid receptor activation 发明人:POSTREL RICHARD 权利人:POSTREL RICHARD 摘要:This invention reverses male pattern baldness by shocking dormant hair follicles out of their androgen induced hibernation phase back to the active hair-growing anagenic phase. The invention integrates two functions: 1) It blocks synthesis of compounds holding the follicles in the telogenic/hibernating phase and 2) It stimulates synthesis of compounds animating the hair-growing/anagenic phase in the follicular activity cycle. One preferred embodiment comprises an enzyme inhibitor blocking the conversion of testosterone to dihydrotestosterone (DHT), a flavonoid simultaneously increasing synthesis of prostaglandins alternative to prostaglandin D2, and a selected cannabinoid compound stimulating restore the hair follicle to its normal growth cycle. This novel trimodal therapy restores the hair follicles to their normal cycling processes and maintains these restorative properties so long as this rebalance in maintained.
专利号:US-5856392-A 优先权日:1996-03-22 标 题 :Higher order star polymers having multiple polyisobutylene arms radiating from a condensed core of siloxanes and a method for the synthesis thereof 发明人:KENNEDY JOSEPH P; OMURA NAOKI; LUBNIN ALEXANDER 权利人:UNIV AKRON 摘要:The synthesis and characterization of novel higher order, multi-arm star polymers comprising polyisobutylene arms connected to condensed cyclosiloxane cores are described. The synthesis has been achieved by hydrosilating olefin-capped (e.g., allyl- or isopropenyl-terminated) polyisobutylene with hydrogencyclosiloxanes carrying a plurality of Si-H groups and simultaneously and competitively converting SiH functions, in the presence of moisture, to Si-OH groups to rapidly self-condense or react with SiH groups to form coupled cyclosiloxane cores via core-core coupling. Thus, higher order stars having many more arms than first order stars can be formed.
摘要:IVL; Swedish Environmental Research Institute, Results from the Swedish National Screening Programme 2004, IVL Report 1643: Subreport 4: Siloxanes. Available from, as of November 17, 2015: 摘要:IVL; Swedish Environmental Research Institute, Results from the Swedish National Screening Programme 2004, IVL Report 1643: Subreport 4: Siloxanes. Available from, as of Aug 18, 2015: 摘要:Mazzoni SM et al; pp. 53-81 in Handb Environ Chem, Vol. 3, Chandra G, ed., Berlin, Germany: Springer (1997) 摘要:EPA/Office of Pollution Prevention and Toxics; High Production Volume (HPV) Challenge Program. Available from the Database Query page at: 摘要:Franke C et al; Chemosphere 29: 1501-14 (1994)