CAS: 40594-30-7; (2,4-Difluorophenyl)Hydrazine

相似化合物

51523-79-6 119452-66-3 502496-26-6

上下游产品

CAS号40594-29-4 (2,4-Difluoroph... | CAS号158386-97-1 3-(2-甲基-3-呋喃)-3-氧丙腈 | CAS号371-14-2 4-氟苯肼 | CAS号37847-52-2 2,4-二氟联苯 | CAS号618098-78-5 1-(2,4-DIFLUORO... | CAS号40594-09-0 氟西吲哚

(2,4-二氟苯基)肼盐酸盐(1:1)置于sodium Carbonate体系中,用 水,乙酸乙酯 作为反应溶剂,化学反应 1.33H,以98%的收率获得产物2,4-二氟苯肼
参考文献:Pyrazolones As Inhibitors Of 11B-Hydroxysteroid Dehydrogenase
标题:Pyrazolones As Inhibitors Of 11B-Hydroxysteroid Dehydrogenase
摘要:本文提供了以下式(I)的化合物: 以及其药学上可接受的盐,其中取代基如规范中所披露的那样.这些化合物及含有它们的药物组合物对于治疗诸如ii型糖尿病和代谢综合征等疾病是有用的.

专利信息

专利号:US-11040938-B2
优先权日:2016-07-27
标 题 :Continuous flow process for the synthesis of phenylhydrazine salts and substituted phenylhydrazine salts
发明人：MA BING; PAN SHUAI
权利人:SHANGHAI HYBRID—CHEM TECH; SHANGHAI HYBRID CHEM TECH
摘要:The present invention provided a continuous flow process for the synthesis of phenylhydrazine salts and substituted phenylhydrazine salts. Diazotization, reduction, acidic hydrolysis and salifying with acids are innovatively integrated together. Using acidic liquids of aniline or substituted aniline, diazotization reagents, reductants and acids as raw materials, phenylhydrazine derivative salts is obtained through the synthesis process, which is a three-step continuous tandem reaction including diazotization, reduction, acidic hydrolysis and salifying. The described synthesis process is a kind of integrated solutions, which is carried out in an integrated reactor. The feed inlets of the integrated reactor are continuously filled with raw materials. In the integrated reactor, diazotization, reduction, acidic hydrolysis and salifying are carried out continuously and orderly, and phenylhydrazine salts or substituted phenylhydrazine salts is obtained in the outlet of the integrated reactor without interruption. The total reaction time is no more than 20 min.

专利号:US-2019152896-A1
优先权日:2016-07-27
标题 :Continuous Flow Process For the Synthesis of Phenylhydrazine Salts and Substituted Phenylhydrazine Salts

专利号:US-4160862-A
优先权日:1972-06-12
标 题 :1-Acyl-3-(amino-lower-alkyl)indoles
发明人：ZENITZ BERNARD L
权利人:STERLING DRUG INC
摘要:1-Acyl-3-(amino-lower-alkyl)indoles, useful as anti-inflammatory agents, are prepared either by acylation of a 3-(amino-lower-alkyl)indole; by Fisher indole synthesis from an N'-acylphenylhydrazine and an amino-lower-alkanone; by alkylation of an amine with a 1-acyl-3-(halo-lower-alkyl)indole; or by reductive alkylation of a 1-acyl-3-indole-lower-alkylcarboxaldehyde.

专利号:US-4021431-A
优先权日:1972-06-12
标 题:3-(Piperidino-lower-alkyl)-indoles
发明人：ZENITZ BERNARD L
权利人:STERLING DRUG INC
摘要:1-Acyl-3-(amino-lower-alkyl)indoles, useful as anti-inflammatory agents, are prepared either by acylation of a 3-(amino-lower-alkyl)indole; by Fisher indole synthesis from an N'-acylphenylhydrazine and an amino-lower-alkanone; by alkylation of an amine with a 1-acyl-3-(halo-lower-alkyl)indole; or by reductive alkylation of a 1-acyl-3-indole-lower-alkylcarboxaldehyde.

专利号:CN-107793362-A
优先权日:2016-08-30
标题:Synthesis and application of a kind of phenylpyridazinone derivatives