CAS: 3695-24-7; 2-Hydroxy-2-(3-Hydroxy-4-Methoxyphenyl)Acetic Acid

该化合物是一种属于酚酸类的手性化合物,其特点是存在一个氢氧基组和一个附属于甲状腺酸结构的甲氧基组,有助于其生物活动,该化合物一般是白色的脱白晶状固体,在水和有机溶剂中可溶解,反映其水氧化物组的极性,其分子结构允许与生物系统进行潜在互动,使其在药理学研究中引起兴趣,该化合物经常因其在新陈代谢途径中的作用及其潜在的治疗应用,特别是在甲酸酐代谢性新陈代谢学方面,受到调查.作为种族混合物,该化合物含有两种对映剂,可能显示不同的生物活动.适当的处理和储存条件对于在研究和应用环境中保持其稳定性和有效性至关重要.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

合成工艺路线路线简述

    📜Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于氢氧化钾体系中,化学反应生成 4-羟基-3-甲氧基苦杏仁酸
    参考文献:Lamanna; Ghislandi,Gazzetta Chimica Italiana,1959,Vol. 89,P. 1231,1236
    标题:Lamanna; Ghislandi,Gazzetta Chimica Italiana,1959,Vol. 89,P. 1231,1236

    海关参考信息

    专利信息


    专利号:US-9453037-B2
    优先权日:2011-07-28
    标 题 :Methylphenidate-prodrugs, processes of making and using the same
    发明人:GUENTHER SVEN; CHI GUOCHEN; BERA BINDU; MICKLE TRAVIS; BERA SANJIB
    权利人:KEMPHARM INC; KEMPHARM INC
    摘要:The present technology is directed to prodrugs and compositions for the treatment of various diseases and/or disorders comprising methylphenidate, or methylphenidate derivatives, conjugated to at least one alcohol, amine, oxoacid, thiol, or derivatives thereof. In some embodiments, the conjugates further include at least one linker. The present technology also relates to the synthesis of methylphenidate, or methylphenidate derivatives, conjugated to at least one alcohol, amine, oxoacid, thiol, or derivatives thereof or combinations thereof.

    专利号:US-2007225490-A1
    优先权日:2003-12-15
    标 题:Cationic Oligomer of a Saccharide for Resolving Enantiomers and Asymmetric Synthesis
    发明人:CHING CHI B; YOUNG DAVID J; MUDERAWAN I WAYAN; ONG TENG T; NG SIU C
    权利人:SELEX SENSORS & AIRBORNE SYS
    摘要:A cationic oligomer of a saccharide, wherein the saccharide is functionalized by a cationic group, for example an ammonium, phosphonium, imidazolium, or pyridinium group. In a preferred embodiment, the cationic oligomer of a saccharide is a cationic cyclodextrin. There is also provided a use of the cationic oligomer of a saccharide as a chiral agent for resolving enantiomers by a chromatographic method or an asymmetric synthesis.

    专利号:US-8361516-B2
    优先权日:2006-08-03
    标 题:Composition comprising sarsasapogenin
    发明人:LINTNER KARL; MAS CHAMBERLIN CLAIRE
    权利人:SEDERMA SA; LINTNER KARL; MAS CHAMBERLIN CLAIRE
    摘要:The présent invention relates to a composition comprising sarsasapogenin or a plant extract containing it in order to improve the gêneral state of the skin and in particular to improve and/or embellish any part of the body showing a déficit in lipids. More particularly, the invention is directed to a cosmetic method to improve the figure, comprising the step of topically applying to the skin a cosmetic or dermopharmaceutical composition comprising sarsasapogenin to favour the expansion and/or the formation of the subcutaneous adipose tissue, and/or to favour the lipid synthesis in the epidermis.

    专利号:WO-2005056609-A1
    优先权日:2003-12-15
    标题 :Cationic oligomer of a saccharide for resolving enantiomers and asymmetric synthesis

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    参考标题:Methylphenidate-Prodrugs, Processes Of Making And Using The Same
    摘要:The Present Technology Is Directed To Prodrugs And Compositions For The Treatment Of Various Diseases And/or Disorders Comprising Methylphenidate, Or Methylphenidate Derivatives, Conjugated To At Least One Alcohol, Amine, Oxoacid, Thiol, Or Derivatives Thereof. In Some Embodiments, The Conjugates Further Include At Least One Linker. The Present Technology Also Relates To The Synthesis Of Methylphenidate, Or Methylphenidate Derivatives, Conjugated To At Least One Alcohol, Amine, Oxoacid, Thiol, Or Derivatives Thereof Or Combinations Thereof.

    合成参考文献


    摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
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