专利号:US-9453037-B2 优先权日:2011-07-28 标 题 :Methylphenidate-prodrugs, processes of making and using the same 发明人:GUENTHER SVEN; CHI GUOCHEN; BERA BINDU; MICKLE TRAVIS; BERA SANJIB 权利人:KEMPHARM INC; KEMPHARM INC 摘要:The present technology is directed to prodrugs and compositions for the treatment of various diseases and/or disorders comprising methylphenidate, or methylphenidate derivatives, conjugated to at least one alcohol, amine, oxoacid, thiol, or derivatives thereof. In some embodiments, the conjugates further include at least one linker. The present technology also relates to the synthesis of methylphenidate, or methylphenidate derivatives, conjugated to at least one alcohol, amine, oxoacid, thiol, or derivatives thereof or combinations thereof.
专利号:US-2007225490-A1 优先权日:2003-12-15 标 题:Cationic Oligomer of a Saccharide for Resolving Enantiomers and Asymmetric Synthesis 发明人:CHING CHI B; YOUNG DAVID J; MUDERAWAN I WAYAN; ONG TENG T; NG SIU C 权利人:SELEX SENSORS & AIRBORNE SYS 摘要:A cationic oligomer of a saccharide, wherein the saccharide is functionalized by a cationic group, for example an ammonium, phosphonium, imidazolium, or pyridinium group. In a preferred embodiment, the cationic oligomer of a saccharide is a cationic cyclodextrin. There is also provided a use of the cationic oligomer of a saccharide as a chiral agent for resolving enantiomers by a chromatographic method or an asymmetric synthesis.
参考标题:Methylphenidate-Prodrugs, Processes Of Making And Using The Same 摘要:The Present Technology Is Directed To Prodrugs And Compositions For The Treatment Of Various Diseases And/or Disorders Comprising Methylphenidate, Or Methylphenidate Derivatives, Conjugated To At Least One Alcohol, Amine, Oxoacid, Thiol, Or Derivatives Thereof. In Some Embodiments, The Conjugates Further Include At Least One Linker. The Present Technology Also Relates To The Synthesis Of Methylphenidate, Or Methylphenidate Derivatives, Conjugated To At Least One Alcohol, Amine, Oxoacid, Thiol, Or Derivatives Thereof Or Combinations Thereof.
合成参考文献
摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198