CAS: 3464-66-2; 1-Methoxycarbonyl-Beta-Carboline

主要参考文献

参考标题:An Efficient Route To 5-Iodo-1-Methylimidazole: Synthesis Of Xestomanzamine A
作者:Francis B Panosyan,Ian Wj Still |发布日期:2001.7.1
摘要:An Efficient And Practical Route To C-5 Functionalized N-Methylated Imidazoles Is Reported. 5-Iodo-1-Methylimidazole Was Synthesized In Four Steps From Imidazole, With Complete Regiospecificity, In 73% Overall Yield. The Synthesis Of Xestomanzamine A, A Marine Natural Product Isolated In 1995 From An Okinawan Sponge Of Xestospongia Sp., Has Been Achieved Using 5-Iodo-1-Methylimidazole In A Modified Grignard Reaction With A β-Carboline Ester Moiety, In An Overall Yield Of 59% Based Upon Imidazole And 53% Based Upon Tryptamine.Key Words: Xestomanzamine A, 5-Iodo-1-Methylimidazole, Methyl β-Carboline-1-Carboxylate.

合成参考文献

摘要:Joule, J. A., Science of Synthesis Knowledge Updates, (2018) 2, 215.
摘要:Joule, J. A., Science of Synthesis Knowledge Updates, (2018) 2, 187.
参考文献:10.1007/s12272-018-1034-2
摘要:Kwon HS, Lee H, Lee JS, Lee K, Choi J, Jang DS. Two new β-carboline alkaloids from the stems of Picrasma quassioides. Archives of Pharmacal Research. 2018 May 03;41(5):513–8. doi: 10.1007/s12272-018-1034-2.