CAS: 135806-59-6; (S)-6-Methoxy-2,5,7,8-Tetramethylchromane-2-Carboxylic Acid

该化合物是可溶水的维生素E模拟物三洛氏合成衍生物.该化合物具有抗氧化性特性,在各种生化和制药应用中具有价值.其结构包括一个甲基醚组,该组与其母化合物相比,提高了溶性性和稳定性. (S)-Trocolox甲基醚经常用于研究氧化性压力及其对生物系统的影响,因为它能够对自由基进行搜索,保护细胞免受氧化性损害.此外,该组可以在旨在改进皮肤健康和防止化妆品氧化性损害的配方方面发挥作用.该化合物的特点是能够捐赠氢原子以释放基质,从而使其中和减轻潜在细胞损害.(S)的指定表明,该组的气质可能展示与对应物不同的特定生物活动,使其成为在药理学和生物化学学方面的重要研究对象.

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相似化合物

53188-07-1 53209-24-8 139658-04-1

上下游产品

-1,2-O-isopropyliden-α-D-glucofuranose3-O-(S)-3,4-Dihydro-6-methoxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-ylcarbonyl-1,2-O-isopropyliden-α-D-glucofuranose -1,2:5,6-di-O-isopropyliden-α-D-glucofuranose3-O-(RS)-3,4-Dihydro-6-methoxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-ylcarbonyl-1,2:5,6-di-O-isopropyliden-α-D-glucofuranose

合成工艺路线路线简述

    📜3-O-<(S)-3,4-Dihydro-6-Methoxy-2,5,7,8-Tetramethyl-2H-1-Benzopyran-2-Ylcarbonyl>-1,2-O-Isopropyliden-α-D-Glucofuranose置于氢氧化钾体系中,用 甲醇 用作溶剂,化学反应 2.0H,以94%的收率获得(S)-6-甲氧基-2,5,7,8-四甲基色烷-2-羧酸
    参考文献:Netscher,Thomas; Gautschi,Iwan,Liebigs Annalen Der Chemie,1992,# 6,P. 543-546
    标题:Netscher,Thomas; Gautschi,Iwan,Liebigs Annalen Der Chemie,1992,# 6,P. 543-546

    海关参考信息

    专利信息


    专利号:US-9217012-B2
    优先权日:2009-04-08
    标题 :Inhibitors of protein tyrosine phosphatases
    发明人:ZHANG ZHONG-YIN; ZHANG SHENG
    权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP
    摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.

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    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1007/s11130-005-9551-4
    摘要:Aminigo ER, Metzger LE. Pretreatment of African yam bean (Sphenostylis stenocarpa): effect of soaking and blanching on the quality of African yam bean seed. Plant Foods Hum Nutr. 2005 Dec;60(4):165–71. doi: 10.1007/s11130-005-9551-4.
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