CAS: 135-61-5; 3-Hydroxy-N-(O-Tolyl)-2-Naphthamide

该化合物是有机化合物,其结构复杂,包括一个环环环系统和一个氨化物功能组,该化合物一般在室温时是固体,可溶于有机溶剂,反映其芳香环造成的疏水性;氢氧基组的存在有助于其氢联结潜力,可影响其溶解性和再活动;经常对其生物活动进行研究,特别是在药用化学方面,该化合物的分子结构可能显示出抗炎或厌食效应等特性,从而可以与生物目标进行各种互动,使其对药用研究感兴趣;应就处理和使用安全数据,如任何化学物质,进行协商,以确保采取适当的预防措施.

结构式图片

欧盟法规

REACH注册ECHA物质C&L通报REACH预注册

上下游产品

o-toluidineo-toluidine 3-Hydroxy-2-naphthoic acid 2-tolyl isothi°Cyanate nitrilotriacetic acid3-(o-tolyl)naphtho[2,3-e][1,2,3]oxathiazin-4(3H)-one 2,2-dioxide o-tolyl-naphtho[2,3-e][1,3]oxazine-2,4-dione3-o-tolyl-naphtho[2,3-e][1,3]oxazine-2,4-dione 3-(phosphonooxy)-N-(o-tolyl)naphthalene-2-carboxamide

合成工艺路线路线简述

    2-羟基-3-萘甲酸置于氯苯,三氯化磷体系中,化学反应生成冰染偶合组分 18
    参考文献:Us2418326
    标题:Us2418326

    海关参考信息

    专利信息


    专利号:US-4074053-A
    优先权日:1973-07-20
    标题 :Aldehydes of 2-hydroxy-naphthalene-3-carboxylic acid arylides
    发明人:HUNGER KLAUS; PAPENFUHS THEODOR
    权利人:HOECHST AG
    摘要:Aldehydes of a 2-hydroxy-naphthalene-3-carboxylic acid arylide of the general formula ##STR1## IN WHICH X represents a hydrogen, chlorine or bromine atom, and Ar represents a naphthyl group, a benzimidazolone, chlorobenzimidazolone, quinazolone, quinoxaline, phthalimide, phthalazine group or a phenyl group which may carry 1 to 3 lower alkyl, lower alkoxy, lower alkylsulfonyl, lower carboalkoxy, halogen, trifluoromethyl, nitro, cyano, lower alkanoylamino, benzoylamino, carboxamido or sulfoamido groups, and a process for their preparation wherein the corresponding 2-hydroxy-naphthalene-3-carboxylic acid arylide is reacted in a lower aliphatic carboxylic acid with hexamethylene tetramine and a mineral acid. n These aldehydes are valuable intermediate products for the synthesis of optical brighteners, pharmaceuticals and, in particular, of azamethine pigments which are obtained by condensation of these aldehydes with suitable amines. The pigments thus obtained are distinguished by good fastness properties and are especially suitable for the printing of paper and the coloring of lacquers, varnishes and plastics.

    专利号:US-3947516-A
    优先权日:1973-07-20
    标 题:Novel aromatic aldehydes and process for preparing them
    发明人:HUNGER KLAUS; PAPENFUHS THEODOR
    权利人:HOECHST AG
    摘要:Aldehydes of a 2-hydroxy-naphthalene-3-carboxylic acid arylide of the general formula ##SPC1## n In which X represents a hydrogen, chlorine or bromine atom, and Ar represents a naphthyl group, a benzimidazolone, chlorobenzimidazoline, quinazolone, quinoxaline, phthalimide, phthalazine group or a phenyl group which may carry 1 to 3 lower alkyl, lower alkoxy, lower alkylsulfonyl, lower carboalkoxy, halogen, trifluoromethyl, nitro, cyano, lower alkanoylamino, benzoylamino, carboxamido or sulfonamido groups and a process for their preparation wherein the corresponding 2-hydroxynaphthalene-3-carboxylic acid arylide is reacted in a lower aliphatic carboxylic acid with hexamethylene tetramine and a mineral acid. n These aldehydes are valuable intermediate products for the synthesis of optical brighteners, pharmaceuticals and, in particular, of azamethine pigments which are obtained by condensation of these aldehydes with suitable amines. The pigments thus obtained are distinguished by good fastness properties and are especially suitable for the printing of paper and the coloring of lacquers, varnishes and plastics.

    专利号:US-5389524-A
    优先权日:1989-07-28
    标 题:Method and a system for quantitatively monitoring a chemical component dissolved in a liquid medium
    发明人:LARSEN BJORN E H; VINTHER ARNE; MOLLER POUL; THORSSON JORN R; SOEBERG HENRIK; SORENSEN JESPER L; LARSEN LYKKE B
    权利人:KOEGE KEMISK VAERK
    摘要:PCT No. PCT/DK90/00196 Sec. 371 Date Mar. 24, 1992 Sec. 102(e) Date Mar. 24, 1992 PCT Filed Jul. 30, 1990 PCT Pub. No. WO91/02254 PCT Pub. Date Feb. 21, 1991.A method and apparatus for quantitatively monitoring a chemical component dissolved in a liquid medium utilize the creation, in a measurement cell, of an interface zone between the liquid medium and an analytical reagent or reference solution. The concentration or amount of the chemical component are determined by the measurement of a value of a measurement parameter in the interface zone, and the derivation from that value of the concentration or amount of the component in comparison with a baseline or reference value measured for the reagent or reference solution alone. Matrix effects and ghosting errors are avoided. The method and apparatus can be used advantageously for on-line optimization and control of industrial, chemical and biological processes, such as chemical reactions in progress, coupling reactions for the synthesis of azo compounds, and the monitoring of in vivo or in vitro biological systems as well as for conventional analytical purposes.

    专利号:CN-106588692-A
    优先权日:2016-12-06
    标题:A method for improving the diazotization reaction speed and conversion rate of weakly basic primary aramides and its application in the synthesis of azo-based organic pigments

    专利号:CN-102093742-B
    优先权日:2011-01-27
    标 题 :Synthesis method of azoic coupling component AS-D series pigment for aqueous application system and product obtained by synthesis method

    专利号:DE-2606905-A1
    优先权日:1976-02-20
    标 题:PROCESS FOR PUMP COLORING OR PRINTING OF MATERIALS MADE OF SYNTHESIS FIBERS AND THEIR MIXTURES WITH CELLULOSE FIBERS
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    合成参考文献


    参考文献:10.1023/b:biry.0000026192.26188.b9
    摘要:Radenovic L, Kartelija G. Effect of chlorpromazine on human and murine intracellular carboxylesterases. Biochemistry (Mosc). 2004 Apr;69(4):381–6. doi: 10.1023/b:biry.0000026192.26188.b9.
    参考文献:10.1007/bf00464618
    摘要:Lampert F, Phebus CK, Huhn D, Meyer G, Greifenegger M. Leukemic xanthomatosis with a missing No. 9 chromosome. European Journal of Pediatrics. 1972 Sep;112(3):251–60. doi: 10.1007/bf00464618.
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