CAS: 115900-75-9; Cgp 46700

该化合物是金属离子,使其对各种应用,包括生物化学和药用化学感兴趣,它表现出潜在的抗氧化活动,并可能在生物系统中的金属离子软静中发挥作用,氢氧基组的存在有助于其在极溶剂中的溶性,而乙基组则加强其脂性.此外,该化合物的结构特征可能会影响其生物活动,使其成为药理学和毒理学研究的主体.

结构式图片

相似化合物

30652-11-0 30652-12-1 118178-79-3

欧盟法规

C&L通报

上下游产品

2-ethyl-3-hydroxy-4-pyranone ethylamine 3-(benzyloxy)-2-ethyl-4H-pyran-4-one

合成工艺路线路线简述

    📜2-乙基-3-苯基甲氧基吡喃-4-酮置于palladium On Activated Charcoal 盐酸,氢气体系中,用 甲醇,乙醇 用作溶剂,化学反应 6.0H,反应生成1,2-二乙基-3-羟基吡啶-4(1H)-酮
    参考文献:Burgess,John; Fawcett,John; Patel,Marttand S.,Journal Of Chemical Research,Miniprint,1993,# 2,P. 214-246
    标题:Burgess,John; Fawcett,John; Patel,Marttand S.,Journal Of Chemical Research,Miniprint,1993,# 2,P. 214-246

    海关参考信息

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1016/s0162-0134(99)00029-x
    摘要:Desroches S, Biron F, Berthon G. Aluminum speciation studies in biological fluids. Part 5. A quantitative investigation of A1(III) complex equilibria with desferrioxamine, 2,3-dihydroxybenzoic acid, Tiron, CP20 (L1), and CP94 under physiological conditions, and computer-aided assessment of the aluminum-mobilizing capacities of these ligands in vivo. J Inorg Biochem. 1999 May 30;75(1):27–35. doi: 10.1016/s0162-0134(99)00029-x.
    参考文献:10.1016/0003-9861(92)90687-r
    摘要:Hartley A, Rice-Evans C. The chelation of nonheme iron within sickle erythrocytes by the hydroxypyridinone chelator CP094. Archives of Biochemistry and Biophysics. 1992 Sep;297(2):377–82. doi: 10.1016/0003-9861(92)90687-r.
    摘要:Hoyes KP, Hider RC, Porter JB. Cell cycle synchronization and growth inhibition by 3-hydroxypyridin-4-one iron chelators in leukemia cell lines. Cancer Res. 1992 Sep 01;52(17):4591–9.
    参考文献:10.1021/jm00030a005
    摘要:el-Jammal A, Howell PL, Turner MA, Li N, Templeton DM. Copper complexation by 3-hydroxypyridin-4-one iron chelators: structural and iron competition studies. J Med Chem. 1994 Feb 18;37(4):461–6. doi: 10.1021/jm00030a005.
    参考文献:10.1182/blood.v89.3.1045
    摘要:Smith AG, Clothier B, Francis JE, Gibbs AH, De Matteis F, Hider RC. Protoporphyria Induced by the Orally Active Iron Chelator 1,2-diethyl-3-hydroxypyridin-4-one in C57BL/10ScSn Mice. 1997 Feb 01;89(3):1045–51. doi: 10.1182/blood.v89.3.1045.
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