CAS: 1072-98-6; 2-Amino-5-Chloropyridine

上下游产品

CAS号504-29-0 2-氨基吡啶 | CAS号52092-47-4 2-硝基-5-氯吡啶 | CAS号74405-03-1 2,2-dimethyl-3-... | CAS号1851-22-5 3-氯吡啶N-氧化物 | CAS号15128-82-2 3-羟基-2-硝基吡啶 | CAS号15128-91-3 2,6-dinitropyri... | CAS号101079-67-8 3-氯-2,6-二硝基吡啶 | CAS号64-17-5 乙醇 | CAS号10461-91-3 N-(5-chloropyri... | CAS号33421-40-8 2-氨基-5-苯基吡啶 | CAS号330858-13-4 6-氯-2-甲基咪唑并[1,2... | CAS号3167-49-5 6-氨基烟酸 | CAS号5437-33-2 3,5-二氯-2-羟基吡啶 | CAS号503536-75-2 5-(4-甲氧基苯基)-2-氨基吡啶 | CAS号503536-73-0 5-(4-氟苯基)-2-氨基吡啶 | CAS号40473-01-6 2-溴-5-氯吡啶 | CAS号2516-40-7 2-溴-1,3-苯并噻唑 | CAS号59128-02-8 乙基(6-氯咪唑并[1,2-a...

2-氨基吡啶置于n-氯代丁二酰亚胺,二氟溴乙酸,2,4,5,6-四(9H-咔唑-9-基)异酞腈体系中,用 四氢呋喃 用作溶剂,化学反应 0.5H,以54%的收率获得2-氨基-5-氯吡啶
参考文献:通过光/有机共催化(杂)苯胺的 C-H 氯化
标题:通过光/有机共催化(杂)苯胺的 C-H 氯化
摘要:氯化(杂)苯胺是一类重要的结构基序,广泛存在于合成结构单元和药物中.尽管最近取得了进展,但直接苯胺氯化仍然存在邻/对和单/多氯化选择性问题.在此,我们公开了一种用于苯胺的光氧化还原和有机共催化氯化方法.该方法具有很好的底物通用性和优异的单氯化选择性.这种方法的另一个优点是药物分子的后期修饰,这将在药物化学中有用.
Doi:10.1039/d2Ob00834C

专利信息

专利号:EP-0332033-A2
优先权日:1988-03-11
标 题:N-cyclopropyl anilines and their use in processes for the synthesis of 1-cyclopropyl-quinolone-carboxylic acids and their derivatives
发明人：SCHRIEWER MICHAEL DR; PETERSEN UWE DR; GROHE KLAUS DR; KREBS ANDREAS DR
权利人:BAYER AG
摘要:N-Cyclopropylanilines of the formula (IV) in which R<1>, X<1>, X<2>, X<3>, A, Z and R<2> have the meaning given in the description, which are suitable for the preparation of 4-quinolone- 3-carboxylic acids, and processes for the preparation of quinolone- carboxylic acid derivatives using N-cyclopropylanilines.

专利号:US-6531470-B1
优先权日:1998-01-23
标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
发明人：GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
权利人:UPJOHN CO
摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

专利号:US-7405310-B2
优先权日:2001-03-05
标 题:Non-nucleoside reverse transcriptase inhibitors
发明人：LINDSTROM STEFAN; SAHLBERG CHRISTER; WALLBERG HANS; KALYANOV GENAIDY; ODEN LOURDES SALVADOR; NAESLUND LOTTA
权利人:MEDIVIR AB
摘要:This invention relates to non-nucleoside reverse transcriptase inhibitors active against HIV-1 and having an improved resistance and pharmacokinetic profile. The invention further relates to novel intermediates in the synthesis of such compounds and the use of the compounds in antiviral methods and compositions.

专利号:US-6562844-B2
优先权日:1998-01-23
标 题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
发明人：GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
权利人:UPJOHN CO
摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

专利号:US-7002020-B1
优先权日:1998-01-23
标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
发明人：GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V
权利人:UPJOHN CO
摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

专利号:CS-225006-B1
优先权日:1979-10-25
标题:Process for the preparation of intermediates for the synthesis of unsymmetrical quinoline monoazacyanine dyes