五氯酚置于四乙基溴化铵体系中,用 甲醇 作为反应溶剂,化学反应生成 2,4,5-三氯苯酚 参考文献:Electroreduction Of Organic Compounds,34 [1]. Cathodic Dehalogenation Of Chloroarenes With Electron-Donating Substituents 标题:Electroreduction Of Organic Compounds,34 [1]. Cathodic Dehalogenation Of Chloroarenes With Electron-Donating Substituents 摘要:氯代芳烃的电化学还原与供电取代基(如氯甲苯,-苯甲醚和-酚)进行研究.在铅或碳阴极下,在各种溶剂支持电解质的电位静态和电流静态条件下进行制备电解.在适当条件下,可能对具有两个或更多氯取代基的化合物进行部分和主要区域选择性的去氯化.尤其是在对位,替换一个单独的氯取代基是困难的.因此,高度有毒和持久的寡氯衍生物可以转化为氯化程度较低的问题较少的化合物.通过电还原,也可以显着降低受氯化酚和nitrofen®污染的土壤提取物等实际材料的氯含量. DOI:10.1515/znb-2003-1206
专利号:WO-0100609-A1 优先权日:1999-06-29 标题:Method for synthesis of n-homocysteine thiolactonyl retinamide 发明人:KAZIMIR MICHAEL; WILSON RAY E II 权利人:UNIV BAYLOR; KAZIMIR MICHAEL; WILSON RAY E II 摘要:The present invention describes methods of synthesis for N-homocysteine thiolactonyl retinamide (thioretinamide), a compound that has anticancer and antiatherogenic properties. The present invention further describes methods for the synthesis of N-homocysteine thiolactonyl retinamido cobalamin (thioretinaco), a compound that has potential anticancer, antineoplastic, antiviral, and antiatherogenic properties.
专利号:US-4242256-A 优先权日:1977-03-15 标 题 :Synthesis of peptide analogues 发明人:SHARPE ROBERT; SZELKE MICHAEL 权利人:SHARPE ROBERT; SZELKE MICHAEL 摘要:Compounds being analogues of a dipeptide in which the nitrogen atom of the linking amide group of the dipeptide is replaced by trivalent group ##STR1## and in which, optionally, the carbonyl function of this linking group is replaced by the divalent group --CH 2 -- are of value in the synthesis of isosterically modified peptides.
专利号:US-4939112-A 优先权日:1988-10-06 标 题:Catalyst for synthesis of vesicular phenoxy resins 发明人:BENNETT EVERETT W 权利人:JAMES RIVER PAPER CO 摘要:A catalyst for synthesis of vesicular phenoxy resins is disclosed. The catalyst includes a water-insoluble complex of a hydric phenol and a quaternary ammonium or phosphonium salt of the hydric phenol. Preferably, the hydric phenol is an intermediate of the phenoxy resin being produced. Dihydric phenols, such as sulfonyldiphenol are preferred. The invention further relates to a reaction medium for polymerization of phenoxy resins including the above-described catalyst and a solvent medium capable of dissolving the phenoxy resins and otherwise not interfering with the polymerization reaction. The solvent medium is advantageously free of toxic Methyl Cellosolve.
专利号:US-7696389-B2 优先权日:2006-03-24 标 题 :Method for reducing microcontaminants during synthesis of pentachlorophenol 发明人:SAVAGE PHILLIP E; YU JIANLI 权利人:UNIV MICHIGAN 摘要:A method for reducing contaminants during synthesis of pentachlorophenol includes providing a phenol-based starting material and a catalyst, which form a reaction mixture. A chlorine flow is introduced so that it is in contact with the reaction mixture, and the starting material and chlorine are reacted via a temperature-programmed reaction. The chlorine flow is terminated at a predetermined temperature prior to an end of the temperature-programmed reaction and/or at a point where the yield of pentachlorophenol is less than about 95%.
专利号:US-6287818-B1 优先权日:2000-04-25 标 题 :Method for synthesis of N-homocysteine thiolactonyl retinamido cobalamin and uses thereof 发明人:KAZIMIR MICHAL; WILSON II F RAY 权利人:UNIV BAYLOR 摘要:The present invention describes methods for the synthesis of N-homocysteine thiolactonyl retinamido cobalamin (thioretinaco), a compound that has potential anticancer, antineoplastic, antiviral, and antiatherogenic properties.
专利号:US-7189849-B2 优先权日:1997-02-10 标 题:Synthesis of acyclic nucleoside derivatives 发明人:LEANNA M ROBERT; RASMUSSEN MICHAEL; HANNICK STEVEN M; TIEN JIEN-HEH J; LUKIN KIRILL A; TIAN ZHENPING; CHANG SOU-JEN; CURTY CYNTHIA B; NARAYANAN BIKSHANDARKOIL A; BELLETTINI JOHN; SHELAT BHADRA; SPITZ TIFFANY 权利人:MEDIVIR AB 摘要:Novel processes towards the synthesis of the antiviral valomaciclovir stearate in which an esterified guanine acetal is reduced to the corresponding alcohol, reacted with an activated amino acid and N-deprotected. The esterified guanine acetal is prepared from a 9-guanine derivative bearing an acyclic hydroxymethylbutylacetal. The processes are amendable to one-pot reactions.
参考标题:1-Propanephosphonic Acid Cyclic Anhydride (T3P) As An Efficient Promoter For The Lossen Rearrangement: Application To The Synthesis Of Urea And Carbamate Derivatives 作者:Vommina Sureshbabu,Basavalingappa Vasantha,Hosahalli Hemantha |发布日期:2010.9 摘要:The Synthesis Of Hydroxamic Acids Starting From Carboxylic Acids Employing 1-Propanephosphonic Acid Cyclic Anhydride (T3P) Activation Is Described. Application Of Ultrasonication Accelerates This Conversion. Further, The T3P Has Also Been Employed To Activate The Hydroxamates, Leading To Isocyanates Via The Lossen Rearrangement. The Isocyanates Were Trapped With Suitable Nucleophiles To Afford The
合成参考文献
参考文献:10.1177/0734242x11411232 摘要:Yazici R, Sekman E, Top S, Varank G, Bilgili MS. Degradation of phenolic compounds in aerobic and anaerobic landfills: a pilot scale study. Waste Manag Res. 2012 May;30(5):542–50. doi: 10.1177/0734242x11411232. 参考文献:10.1002/cssc.201100108 摘要:Ren Q, Hou Z, Wang Y, Zhang H, Yang S. Noncovalent Interactions of Metalloporphyrins with Polyamidoamine Dendrimers Give Rise to Efficient Catalytic Systems for H2O2 Oxidation of Trichlorophenol in Water. ChemSusChem. 2011 Jul 12;4(8):1063–7. doi: 10.1002/cssc.201100108. 参考文献:10.1007/s00425-011-1474-0 摘要:Hall D, Kim KH, De Luca V. Molecular cloning and biochemical characterization of three Concord grape (Vitis labrusca) flavonol 7-O-glucosyltransferases. Planta. 2011 Dec;234(6):1201–14. doi: 10.1007/s00425-011-1474-0.