CAS: 75-68-3; 1-Chloro-1,1-Difluoroethane

该化合物是一种无色,挥发性液体,属于卤化烃类别,其特点是沸点低,蒸气压力高,在气溶胶配方中用作制冷剂和推进剂;化合物的分子式为C2HClF2,表明存在一个氯原子和两个与双碳乙烷主干管相连的氟化原子;在正常条件下相对稳定,但可以在高温下分解,可能释放有毒气体;1-Chloro-1,1-二氟乙烷不易燃,在水中具有中等溶性,同时有机溶剂中溶性较高;由于其消耗臭氧的潜力,根据各种环境保护法对其使用进行规范;在处理该物质时,必须采取安全防范措施,因为它会引起呼吸刺激,长期接触可能会对健康造成潜在风险.

结构式图片

欧盟法规

REACH注册ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

CAS号75-35-4 1,1-二氯乙烯 | CAS号71-55-6 1,1,1-三氯乙烷 | CAS号75-37-6 1,1-二氟乙烷 | CAS号75-38-7 偏氟乙烯 | CAS号3518-66-9 1-chloroethanes... | CAS号594-72-9 二氯硝基乙烷 | CAS号1717-00-6 一氟二氯乙烷 | CAS号2317-91-1 1-氯-1-氟乙烯 | CAS号2834-23-3 氯二氟乙酸酐 | CAS号74-88-4 碘甲烷 | CAS号354-21-2 1,2,2-三氯-1,1-二氟乙烷 | CAS号76-11-9 1,1,1,2-四氯-2,2-二氟乙烷 | CAS号1649-08-7 二氯二氟乙烷 | CAS号75-38-7 偏氟乙烯 | CAS号420-46-2 三氟乙烷 | CAS号811-95-0 1-氟-1,1,2-三氯乙烷 | CAS号79-01-6 三氯乙烯 | CAS号354-14-3 1-氟-1,1,2,2-四氯乙烷 | CAS号76-01-7 五氯乙烷 | CAS号2317-91-1 1-氯-1-氟乙烯

合成工艺路线路线简述

  • 合成目标产物 1-Chloro-1,1-Difluoroethane 主要起始原料 Vinylidene Chloride
  • (文献来源)合成步骤主要原料 Vinylidene Chloride
📜三氯乙烷置于antimony Dichloride Trifluoride,三氟化锑体系中,化学反应生成 1-氯-1,1-二氟乙烷
参考文献:Henne; Renoll,Journal Of The American Chemical Society,1936,Vol. 58,P. 888
标题:Henne; Renoll,Journal Of The American Chemical Society,1936,Vol. 58,P. 888

海关参考信息

专利信息


专利号:US-11926589-B2
优先权日:2019-07-09
标 题 :Process for the synthesis of non-racemic cyclohexenes
发明人:REISMAN SARAH; ROMBOLA MICHAEL; LADD CAROLYN L; MCLAUGHLIN MARTIN JOHN; ZUEND STEPHAN; GOETZ ROLAND
权利人:BASF CORP; CALIFORNIA INST OF TECHN
摘要:This invention relates to a process for the synthesis of a non-racemic cyclohexene compound of formula (I) by a Diels-Alder reaction of a compound of formula (II) with a compound of formula (III) wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 and Y have the meanings as defined in the description in the presence of a catalyst comprising at least one m-valent metal cation M m+ wherein the metal M is selected from Scandium (Sc), Yttrium (Y), Lanthanum (La), Cerium (Ce), Praseodymium (Pr), Neodymium (Nd), Promethium (Pm), Samarium (Sm), Europium (Eu), Gadolinium 15 (Gd), Terbium (Tb), Dysprosium (Dy), Holmium (Ho), Erbium (Er), Thulium (Tm), Ytterbium (Yb), Lutetium (Lu), Gallium (Ga) and Indium (In), and m is an integer of 1, 2 or 3, and a chiral ligand of the formula (IV) wherein R 10a , R 10b , R 10c , R 10d , R 10a′ , R 10b′ , R 10c′ , R 10d′ , Z and Z′ have the meanings as defined in the description.

专利号:US-9126995-B2
优先权日:2011-11-08
标题:Method for catalytic asymmetric synthesis of optically active isoxazoline compound and optically active isoxazoline compound
发明人:TOYAMA KEN-ICHI; MORIYAMA YUJI; MATOBA KAZUTAKA; YAOSAKA MANABU; IKEDA EITATSU
权利人:NISSAN CHEMICAL IND LTD
摘要:There is provided a method for catalytic asymmetric synthesis of optically active isoxazoline compound and an optically active isoxazoline compound. A method for catalytic asymmetric synthesis of optically active isoxazoline compound of a formula (6) including reacting an α,β-unsaturated carbonyl compound of a formula (1) and a hydroxylamine in a solvent in the presence of a base by adding a chiral phase transfer catalyst. An optically active isoxazoline compound of a formula (13) that can be synthesized by the method.

专利号:WO-2024105700-A1
优先权日:2022-11-18
标 题:A method for the synthesis of anthranilic amide compounds and intermediates thereof
发明人:MALVIYA NITIN; MAL SANJIB; KLAUSENER ALEXANDER G M
权利人:PI INDUSTRIES LTD
摘要:The present invention discloses a method for the synthesis of a compound of formula (V) or a salt thereof, wherein, R, R1, R2, R3, R4a and R4b are as defined in the detailed description. The method further comprises the synthesis of an anthranilic diamide compound of formula (Z).

专利号:US-2023339844-A1
优先权日:2020-09-17
标题:A process for the synthesis of anthranilic acid/amide compounds and intermediates thereof
发明人:MAHAPATRA TRIDIB; PATRA PRANAB KUMAR; KLAUSENER ALEXANDER G M; MAL SANJIB; SHARMA RAJU
权利人:PI INDUSTRIES LTD; PI INDUSTRIES LTD
摘要:The present invention disclosed a process for the synthesis of compound of formula (Z) or a salt thereof, n n n n n n n n n n wherein, R, R 1 , R 2 , R 3 and R 10 are as defined in the detailed description. The process further comprises the synthesis of an anthranilic diamide compound of formula (I).

专利号:US-2023339906-A1
优先权日:2020-09-26
标 题 :A process for the synthesis of anthranilic acid/amide compounds and intermediates thereof
发明人:SYTHANA SURESH KUMAR; NAGLE PRAMOD; KUMAR VIJAY KUMAR; KANAWADE SHRIKANT BHAUSAHEB; CHANDRE TUKARAM NIVRUTTI; THUBE VINAYAK KISAN; PATIL PRADEEP PRAKASH; SHUKLA SHALINI; SHENDE KANTILAL BALU; PATRA PRANAB KUMAR; KLAUSENER ALEXANDER G M
权利人:PI INDUSTRIES LTD; PI INDUSTRIES LTD
摘要:The present invention discloses a process for the synthesis of compound of formula (VII) or a salt thereof,wherein, R, R1, R2, R3, R4a and R4b are as defined in the detailed description. The process further comprises the synthesis of an anthranilic diamide compound of formula (I).

专利号:WO-2017089470-A1
优先权日:2015-11-27
标 题:Process for the synthesis of aryldiazonium salts using nitrogen oxides in oxygen-containing gas streams, especially from industrial waste gases
发明人:HOFMANN DAGMAR; HOFMANN JOSEFA; HEINRICH MARKUS
权利人:Friedrich-Alexander-Universität Erlangen-Nürnberg
摘要:The present invention relates to a process for the synthesis of aryldiazonium salts using nitrogen oxides in oxygen-containing gas streams, especially from industrial waste gases.

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品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

合成参考文献


摘要:Ameduri, B., Science of Synthesis Knowledge Updates, (2014) 3, 320.
摘要:Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure, Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982, -(53), 1982
摘要:LILLIAN ET AL; J ENVIRON SCI HEALTH A-11 (12): 687-710 (1976)
摘要:Currance, P.L. Clements, B., Bronstein, A.C. (Eds).; Emergency Care For Hazardous Materials Exposure. 3Rd edition, Elsevier Mosby, St. Louis, MO 2005, p. 222
摘要:SRI Consulting. 2009 Directory of Chemical Producers. SRI Consulting. Menlo Park, CA 2009, p. 494
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