CAS: 7377-03-9; Octanohydroxamic Acid

1-硝基辛烷置于甲胺体系中,用 甲醇 作为反应溶剂,化学反应 2.0H,以85%的收率获得产物辛酰氧肟酸
参考文献:Novel Intramolecular Photorearrangement Of Nitronate Anions
标题:Novel Intramolecular Photorearrangement Of Nitronate Anions
摘要:
DOI:10.1021/jo00148A011

专利信息

专利号:US-11414365-B2
优先权日:2018-01-30
标题:Natural 1,2-alkanediols, compositions having natural 1,2-alkanediols and processes for making the same
发明人：BURGO ROCCO V; WRIGHT MICHAEL E; MOSSER GARY B; FEVOLA MICHAEL J
权利人:INOLEX INVESTMENT CORP
摘要:A process is incorporated herein for the synthesis of bio-1,2-alkanediols, comprising: providing a bio-alkene having a carbon chain of about 5 to about 20 carbon atoms and a bio-1-alkene regioselectivity of at least about 80%, at least about 92% and/or at least about 95%; and converting the bio-alkene to a bio-1,2-alkanediol having a carbon chain length of about 5 to about 20 carbon atoms. Methods for treating catalysts which may be incorporated in the process for the synthesis of bio-1,2-alkanediols are also included herein. Such bio-1,2-alkanediols are used in compositions and products alone as antimicrobial materials, or with existing bio-compounds and/or antimicrobials, preservatives, alternative preservation systems and/or hurdle technology components. The bio-1,2-alkanediols incorporate a natural and bio-based pathway for antimicrobial effects in various compositions such as cosmetic, pharmaceutical, industrial and household products.

专利号:US-8754237-B2
优先权日:2006-02-14
标题:Bifunctional histone deacetylase inhibitors
发明人：BRADNER JAMES ELLIOT; MAZITSCHEK RALPH; TANG WEIPING; SCHREIBER STUART L
权利人:BRADNER JAMES ELLIOT; MAZITSCHEK RALPH; TANG WEIPING; SCHREIBER STUART L; HARVARD COLLEGE; DANA FARBER CANCER INST INC
摘要:In recognition of the need to develop novel therapeutic agents and efficient methods for the synthesis thereof, the present invention provides novel bifunctional, trifunctional, or multifunctional compounds for inhibiting histone deacetylases, and pharmaceutically acceptable salts and derivatives thereof. The present invention further provides methods for treating disorders regulated by histone deacetylase activity (e.g., proliferative diseases, cancer, inflammatory diseases, protozoal infections, hair loss, etc.) comprising administering a therapeutically effective amount of an inventive compound to a subject in need thereof. The present invention also provides methods for preparing compounds of the invention.