CAS: 594-65-0; Trichloroacetamide

相似化合物

683-72-7 79-07-2 683-72-7

上下游产品

CAS号98946-18-0 叔丁基三氯乙酰亚胺酯 | CAS号772-33-8 2-羟基-5-硝基溴苄 | CAS号1067910-79-5 (S)-3-methyl-2-... | CAS号81927-55-1 2,2,2-三氯乙酰亚胺苄酯 | CAS号14131-63-6 β-D-Glucopyra... | CAS号76-02-8 三氯乙酰氯 | CAS号545-06-2 三氯乙腈 | CAS号624-76-0 2-碘-1-乙醇 | CAS号598-99-2 三氯乙酸甲酯 | CAS号18271-89-1 Acetamide,2,2,2... | CAS号28460-70-0 2,2,2-trichloro... | CAS号26268-56-4 2,2,2-trichloro... | CAS号3018-12-0 二氯乙腈 | CAS号683-72-7 二氯乙酰胺 | CAS号15436-35-8 Thiophene,1,1,2... | CAS号545-06-2 三氯乙腈 | CAS号34891-76-4 N-HYDROXYMETHYL... | CAS号35077-12-4 N-bromo-2,2,2-t...

三氯乙酸乙酯置于氨体系中,化学反应生成 2,2,2-三氯乙酰胺
参考文献:Clermont,Comptes Rendus Hebdomadaires Des Seances De L'Academie Des Sciences,1901,Vol. 133,P. 737
标题:Clermont,Comptes Rendus Hebdomadaires Des Seances De L'Academie Des Sciences,1901,Vol. 133,P. 737

专利信息

专利号:US-7160517-B2
优先权日:2000-08-18
标题 :Apparatus and methods for the automated synthesis of oligosaccharides
发明人：SEEBERGER PETER H; PLANTE OBADIAH J
权利人:MASSACHUSETTS INST OF TECHNOLG
摘要:One aspect of the present invention relates to an apparatus for the efficient synthesis of oligosaccharides on a solid support, e.g., formed by subunit addition to terminal subunits immobilized on solid-phase particles. In certain embodiments, the apparatus of the present invention is used in combinatorial methods, e.g., as described herein, of synthesizing oligosaccharides.

专利号:US-11566040-B2
优先权日:2019-01-28
标题:Synthesis of O-antigen oligosaccharide compounds of Helicobacter pylori serotype O2
发明人：YIN JIAN; HU JING; LIU ZHONGHUA; QIN CHUNJUN
权利人:UNIV JIANGNAN
摘要:Disclosed is synthesis of an O-Antigen oligosaccharide compound of Helicobacter pylori serotype O2, belonging to the field of organic synthesis. The disclosure obtains O-antigen disaccharide to tetracosasaccharide of Helicobacter pylori serotype O 2 by chemical synthesis. A chemical synthesis method which is quite conducive to production of a glucose-α-lglucosidic bond is developed in the disclosure by a protectant strategy, temperature effect, solvent effect, and additive effect. The method is applied in synthesis of an O-antigen oligosaccharide compound of Helicobacter pylori serotype O2 assembled with an amino linking arm. A saccharide conjugate can be prepared from the synthesized O-antigen oligosaccharide compound of Helicobacter pylori serotype O2 assembled with an amino linking arm together with a carrier protein for immunology researches, playing an important role in preventing and treating Helicobacter pylori.

专利号:US-11548898-B2
优先权日:2017-07-06
标题 :Synthesis of halichondrins
发明人：KISHI YOSHITO; AI YANRAN; YE NING; WANG QIAOYI; YAHATA KENZO; ISO Kentaro; NAINI SANTHOSH REDDY; YAMASHITA SHUJI; LEE JIHOON; OHASHI ISAO; FUKUYAMA TAKASHI
权利人:HARVARD COLLEGE; EISAI R&D MAN CO LTD
摘要:The present invention provides methods for the synthesis of ketones involving a Ni/Zr-mediated coupling reaction. The Ni/Zr-mediated ketolization reactions can be used in the synthesis of halichondrins (e.g., halichondrin A, B, C; homohalichondrin A, B, C; norhalichondrin A, B, C), and analogs thereof. Therefore, the present invention also provides synthetic methods useful for the synthesis of halichondrins, and analogs thereof. Also provided herein are compounds (i.e., intermediates) useful in the synthesis of halichondrins, and analogs thereof. In particular, the present invention provides methods and compounds useful in the synthesis of compound of Formula (H3-A).

专利号:WO-0142264-A1
优先权日:1999-12-10
标 题 :Method for the synthesis of sialylated oligosaccharide donors
发明人：MEHTA SEEMA; GILBERT MICHEL; WAKARCHUK WARREN W; WHITFIELD DENNIS M
权利人:CA NAT RESEARCH COUNCIL; MEHTA SEEMA; GILBERT MICHEL; WAKARCHUK WARREN W; WHITFIELD DENNIS M
摘要:A method for the synthesis of aryl thioglycosides comprising a sialylated residue of β-D-galactose is disclosed. The method consists of preparing by a chemical synthesis a non-sialylated aryl thioglycoside, and enzymatically sialylating the latter with a sialic acid in the presence of a suitable sialyltransferase. The sialylated aryl thioglycoside is then chemically derivatized by standard procedures, to provide a derivative suitable for use as a donor in chemical syntheses of sialylated oligosaccharides. The derivatized sialylated aryl thioglycosides are prepared in high yields, due to reduced number of chemical and purification steps involved in the process. Derivatized aryl thioglycosides useful as building blocks for the synthesis of biologically active sialylated oligosaccharides are also disclosed.

专利号:US-2022395800-A1
优先权日:2019-11-04
标题:Device for automated synthesis of oligo- and polysaccharides
发明人：SEEBERGER PETER H; DANGLAD FLORES JOSE; LE MAI HOANG KIM; PARDO VARGAS ALONSO; SLETTEN ERIC; SALWICZEK MARIO
权利人:MAX PLANCK GESELLSCHAT ZU RFERDERUNG DER WSS E V; GlycoUniverse GmbH & Co KG&A
摘要:The present invention generally relates to automated synthesis technology, and more particularly, to a device and method for automated synthesis of oligo- and polysaccharides on a solid support. In particular the present invention relates to a device for automated synthesis of oligo- and polysaccharides on a solid support comprising a reaction vessel, a reagent storing component, a reagent delivery system, a cooling device for cooling reaction vessel, and a pre-cooling device for pre-cooling the reagents to be supplied.

专利号:US-2004018598-A1
优先权日:2000-05-30
标题 :Bio-intermediates for use in the chemical synthesis of polyketides
发明人：SANTI DANIEL; ASHLEY GARY; MYLES DAVID C
摘要:The present invention relates to compounds made by a subset of modules from one or more polyketide synthase (“PKSâ€?) genes that are used as starting material in the chemical synthesis of novel molecules, particularly naturally occurring polyketides or derivatives thereof. The biologically derived intermediates (“bio-intermediatesâ€?) generally represent particularly difficult compounds to synthesize using traditional chemical approaches due to one or more stereocenters. In one aspect of the invention, an intermediate in the synthesis of epothilone is provided that feeds into the synthetic protocol of Danishefsky and co-workers. In another aspect of the invention, intermediates in the synthesis of discodermolide are provided that feed into the synthetic protocol of Smith and co-workers. By taking advantage of the inherent stereochemical specificity of biological processes, the syntheses of key intermediates and thus the overall syntheses of compounds like epothilone and discodermolide are greaty simplified.