CAS: 54-35-3; 2-(Diethylamino)Ethyl 4-Aminobenzoate (2S,5R,6R)-3,3-Dimethyl-7-Oxo-6-(2-Phenylacetamido)-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate

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CAS号113-98-4 青霉素钾 | CAS号59-46-1 奴夫卡因

Penicillin G Potassium,普鲁卡因置于对羟基苯甲酸丙酯,Plasdone C-30,Rongalite,Sodium Citrate,对羟基苯甲酸甲酯,Lecithin,Carboxymethylcellulose体系中,用 水 作为反应溶剂,化学反应 1.0H,反应生成 普鲁卡因青霉素
参考文献: A Method For Preparing Penicillin G Procaine[fr] Procédé De Préparation De La Procaine Penicillinne G
标题: A Method For Preparing Penicillin G Procaine[fr] Procédé De Préparation De La Procaine Penicillinne G
摘要:制备盐酸青霉素g丙酸盐的过程包括以下步骤:将无活性成分引入第一个混合罐中,并在第一个混合罐中对无活性成分的混合物进行灭菌处理.将盐酸丙胺溶解在第二个混合罐中,然后通过无菌过滤器将第二个混合罐中的内容加入到第一个混合罐中.将青霉素g钾的溶液通过无菌过滤器引入第一个混合罐中,然后混合第一个混合罐中的内容,使盐酸丙胺与青霉素g钾反应反应生成盐酸青霉素g丙酸盐.将得到的悬浮液通过均质器转移到保持罐中,然后将盐酸青霉素g丙酸盐灌装到容器中.

专利信息

专利号:US-11744867-B2
优先权日:2017-02-14
标 题 :Modulation of microbial synthesis of 4-ethylphenol and 4-ethylphenyl sulfate in behavior and disease
发明人：NEEDHAM BRITTANY D; MAZMANIAN SARKIS K; SHARON GIL; FUNABASHI MASANORI; FISCHBACH MICHAEL A; HSIAO ELAINE Y; PATTERSON PAUL H
权利人:CALIFORNIA INST OF TECHN; UNIV CALIFORNIA
摘要:Some embodiments relate to genetically engineered bacterial strains for modulation of levels of the bacterial metabolite 4-ethylphenol (4EP) and its sulfated form, 4-ethylphenyl sulfate (4EPS). In some embodiments, the bacteria reduce or inhibit production of 4EP or 4EPS in the gut of a subject. The bacteria can ameliorate, delay the onset, or reduce the likelihood of one or more symptoms associated with anxiety and/or autism spectrum disorder (ASD) in the subject.

专利号:US-2023248849-A1
优先权日:2020-07-27
标 题:Contrast agents for detection of enzyme activities based on melanin synthesis
发明人：PAGEL MARK D
权利人:UNIV TEXAS
摘要:We disclose a composition, comprising a compound, comprising a melanin precursor that spontaneously synthesizes a melanin when in free form in vivo, and a peptide directly covalently bonded to or indirectly linked to the melanin precursor, wherein the direct covalent bond or indirect link of the peptide to the melanin precursor blocks spontaneous synthesis of the melanin in vivo in the absence of protease activity. We also disclose methods of tumor imaging, tumor detection, diagnosis, and treatment, including methods comprising administering, to a patient suffering from a tumor, the composition; and either surgically resecting the tumor or thermally ablating the tumor, wherein the surgical resection is guided at least in part by contrast imparted by, or the thermally ablating targets cells containing, the melanin, wherein the melanin is spontaneously synthesized in the tumor after administering the composition.

专利号:US-2025002508-A1
优先权日:2020-05-05
标题 :Boronic acid derivatives and synthesis, polymorphic forms, and therapeutic uses thereof
发明人：HECKER SCOTT J; BOYER SERGE HENRI; BIO MATTHEW M; FANG YUANQING; GONZALES DE CASTRO ANGELA; LEFORT LAURENT; ZHU ZUOLIN; LINDER THOMAS
权利人:QPEX BIOPHARMA INC
摘要:Disclosed herein are antimicrobial compounds, polymorphic forms, compositions, pharmaceutical compositions, the method of use and preparation thereof. Some embodiments relate to boronic acid derivatives and their use as therapeutic agents, for example, β-lactamase inhibitors (BLIs).

专利号:WO-2018152133-A1
优先权日:2017-02-14
标题 :Modulation of microbial synthesis of 4-etylphenol and 4-ethylphenol sulfate in behavior and disease

专利号:US-11224624-B2
优先权日:2017-02-14
标 题 :Modulation of microbial synthesis of 4-etylphenol and 4-ethylphenyl sulfate in behavior and disease

专利号:US-2022096575-A1
优先权日:2017-02-14
标 题 :Modulation of microbial synthesis of 4-ethylphenol and 4-ethylphenyl sulfate in behavior and disease