CAS: 40348-66-1; (R)-Butane-1,2-Diol

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1,2-丁二醇置于halohydrin Dehydro-Dehalogenase From Alcaligenes Sp. Ds-S-7G,2,6-二氯靛酚,Phenazine Methosulfate体系中,化学反应生成 (R)-1,2-丁二醇
参考文献:手性c 3和c 4合成单元的微生物分辨率的工业化:从小的开始到主要的操作,个人账户
标题:手性c 3和c 4合成单元的微生物分辨率的工业化:从小的开始到主要的操作,个人账户
摘要:该描述描述了手性c 3和c 4合成单元直至生产阶段的微生物分离度的研究和开发.这些手性c 3和c 4合成单元主要用于生产各种药物,液晶,手性聚合物和天然化合物等新材料以及基础化学研究.该研究始于1983年,工厂建于1994年.该开发仍在进行中,并已扩大到包括c 4在内.手性单元,手性丙二醇等.该项目开始于对环氧氯丙烷装置中活性污泥的简单研究,并经过许多事件和大量研究发展为工业生产.我们描述了这些手性c 3和c 4合成单元的生产过程中,在研发过程中的各种含义和事件流.
DOI:10.1002/adsc.200390050

专利信息

专利号:US-2018297925-A1
优先权日:2015-10-12
标题 :Methods for total synthesis of resolvin e1
发明人：JAGTAP PRAKASH
权利人:SALZMAN LOVELACE INVEST LTD
摘要:Methods for total chemical synthesis of Resolvin E1 (RvE1) include Wittig reaction of two compounds having hydroxyl protecting group in the presence of a strong base, removal of the hydroxyl-protecting groups with a deprotecting reagent to produce a compound having an ester group, and hydrolysis of the ester group to obtain RvE1

专利号:US-8129544-B2
优先权日:2002-10-15
标题:1-substituted-4-nitroimidazole compound and method for preparing the same
发明人：GOTO FUMITAKA; TAKEMURA NORIAKI; OTANI TADAAKI; HASEGAWA TAKESHI; TSUBOUCHI HIDETSUGU; UTSUMI NAOTO; FUJITA SHIGEKAZU; KURODA HIDEAKI; SHITSUTA TAKUYA; SASAKI HIROFUMI
权利人:GOTO FUMITAKA; TAKEMURA NORIAKI; OTANI TADAAKI; HASEGAWA TAKESHI; TSUBOUCHI HIDETSUGU; UTSUMI NAOTO; FUJITA SHIGEKAZU; KURODA HIDEAKI; SHITSUTA TAKUYA; SASAKI HIROFUMI; OTSUKA PHARMA CO LTD
摘要:The present invention relates to a 1-substituted-4-nitroimidazole compound represented by the general formula (1) or a salt thereof, n n(wherein R is a hydrogen atom, a lower alkoxy group-substituted lower alkyl group, a phenyl-lower alkoxy group-substituted lower alkyl group, a cyano-substituted lower alkyl group, a phenyl-lower alkyl group which may have lower alkoxy groups as the substituents in the phenyl ring or a group of the formula —CH 2 R A ; X is a halogen atom or a group of the formula —S(O)n-R 1 ) and method for preparing the same. The compound of the formula (1) is a useful compound as an intermediate for synthesis of various pharmaceutical and agricultural chemicals, particularly, as intermediates for antitubercular agents.

专利号:WO-2017064701-A1
优先权日:2015-10-12
标题 :Methods for total synthesis of resolvin e1

专利号:KR-20180090990-A
优先权日:2015-10-12
标 题:Method for total synthesis of resolvable bean E1

专利号:CA-3001667-A1
优先权日:2015-10-12
标题:Methods for total synthesis of resolvin e1

专利号:US-9328073-B2
优先权日:2011-05-25
标 题 :Alcohol-, diol-, and carbohydrate-substituted indenoisoquinolines as topoisomerase I inhibitors
发明人：CUSHMAN MARK S; POMMIER YVES GEORGE
权利人:CUSHMAN MARK S; POMMIER YVES GEORGE; PURDUE RESEARCH FOUNDATION
摘要:The invention described herein pertains to substituted indenoisoquinoline compounds as described herein, wherein R A , R D , W, X and Y are defined herein, pharmaceutical compositions and formulations comprising the indenoisoquinoline compounds, their synthesis, and methods for their use in the treatment and/or prevention of cancer.