6-硝基藜芦酸置于甲醇,Ammonium Hydroxide,Sodium Hydroxide,镍体系中,化学反应生成6,7-二甲氧基-2,4-喹唑啉二酮 参考文献:Curd Et Al.,Journal Of The Chemical Society,1948,P. 1759,1765 标题:Curd Et Al.,Journal Of The Chemical Society,1948,P. 1759,1765
专利号:US-2008039473-A1 优先权日:2006-08-08 标题:Preparation and utility of substituted quinazoline compounds with alpha-adrenergic blocking effects 发明人:GANT THOMAS G; SARSHAR SEPEHR 权利人:AUSPEX PHARMACEUTICALS INC 摘要:The present disclosure is directed to modulators of alpha-adrenergic receptors and pharmaceutically acceptable salts and prodrugs thereof, the chemical synthesis thereof, and the use of such compounds for the treatment and/or management of hypertension, cardiac failure, prostatitis, and benign prostatic hyperplasia, and any other condition in which it is beneficial to modulate an alpha-adrenergic receptor.
专利号:US-11434243-B2 优先权日:2017-12-19 标 题 :Triazoloquinazolinone synthesis 发明人:JAGUSCH THOMAS; ZENHORST PETER ADRIANUS HUBERTUS; VAN DER AA PAULA ANNA ADRIANA; VERSPUI GOVERT ARIE; KAS MARTIN; SCIGELOVA MARTINA 权利人:GABATHER AB 摘要:The invention relates to an improved process for preparing triazoloquinazolinones of Formula (I),including 9-benzyl-2-(4-methylphenyl)-2,6-dihydro[1,2,4]triazolo[4,3-c]quinazoline-3,5-dione, pharmaceutical compositions comprising the compounds of Formula (I), including 9-benzyl-2-(4-methylphenyl)-2,6-dihydro[1,2,4]triazolo[4,3-c]quinazoline-3,5-dione, prepared by the improved process, and methods of treatment using the compounds of Formula (I), including 9-benzyl-2-(4-methylphenyl)-2,6-dihydro[1,2,4]triazolo[4,3-c]quinazoline-3,5-dione, prepared by the improved process.
专利号:ES-2934885-T3 优先权日:2017-12-19 标题 :Synthesis of triazoloquinazolinone
专利号:ES-2651450-T3 优先权日:2005-12-01 标 题 :Enzymatic coding methods for efficient synthesis of large libraries