CAS: 2650-40-0; 3,3,5,5-Tetramethylcyclohexan-1-Ol

相似化合物

14376-79-5 116-02-9 767-12-4

上下游产品

3,3,5,5-tetramethylcyclohexanone 3,3,5,5-Tetramethylcyclohexene 3,3,5,5-tetramethylcyclohexanone 3,3,5,5-tetramethylcyclohexyl chloride 3,3,5,5-tetramethylcyclohexyl bromide

📜3,3,5,5-四甲基环己酮置于sodium Tetrahydroborate,Silica Gel体系中,化学反应 10.0H,以88%的收率获得3,3,5,5-四甲基环己醇
参考文献:探索催化剂功能--手性聚硼酸盐阴离子催化剂的电子调制
标题:探索催化剂功能--手性聚硼酸盐阴离子催化剂的电子调制
摘要:Vapol 和 Vanol 的硼酸配合物是一种手性阴离子平台,可作为不对称催化的多功能分级平台.该平台的结构基础是手性聚硼酸酯核心,它将醇(或酚)和拱形联芳基配体共价连接在一起.聚硼酸酯平台通过反应底物原位组装,因此可以由各种醇(或酚)和双酚配体快速组装出多重手性催化剂,用于筛选催化剂活性.在本研究中,探讨了硼氧酸酯催化剂中苯酚/醇组分的空间和电子性质的变化,以揭示它们对催化不对称氮丙啶化反应中不对称诱导的影响.哈米特的研究与两种底物在对映步骤中氢键结合到硼氧酸酯核心的机制是一致的.Hammett 研究的结果得到了一项计算研究的支持,其中发现,与阴离子硼氧酸盐核心键合的质子化亚胺氢的 H-O 距离随着并入阴离子硼氧酸盐核心的苯酚单元的电子释放能力的增加而减小.硼酸.结果与硼氧酸酯催化剂充当路易斯酸并通过路易斯酸/路易斯碱相互作用活化亚胺的机制不一致.Hammett 研究的结果得到了一项计算
Doi:10.1021/acs.Joc.1C01769

专利信息

专利号:WO-0140193-A1
优先权日:1999-12-03
标题:Method for the synthesis of pyrazolines
发明人：BOLDI ARMEN M
权利人:CHEMRX ADVANCED TECHNOLOGIES I; BOLDI ARMEN M
摘要:The present invention provides a method for the synthesis of compounds of Formula (I). Also claimed are novel intermediates and their methods of synthesis.

专利号:US-2002103381-A1
优先权日:2000-11-30
标 题 :Method for the synthesis of pyrazolines
发明人：BOLDI ARMEN M
摘要:The present invention provides a method for the synthesis of compounds of Formula I: n n n Also claimed are novel intermediates and their methods of synthesis.

专利号:US-2004053999-A1
优先权日:1997-09-17
标题 :Novel compounds and methods for synthesis and therapy
发明人：BISCHOFBERGER NORBERT W; DAHL TERRENCE C; HITCHCOCK MICHAEL J M; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; MILLS ROGER G; WILLIAMS MATTHEW A
摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.

专利号:US-6225341-B1
优先权日:1995-02-27
标 题:Compounds and methods for synthesis and therapy
发明人：BISCHOFBERGER NORBERT W; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; WILLIAMS MATTHEW A
权利人:GILEAD SCIENCES INC
摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.