CAS: 2318-25-4; Ethyl 3-Ethoxy-3-Iminopropionate Hydrochloride

相似化合物

10344-69-1 2225144-12-5 27317-59-5

上下游产品

CAS号64-17-5 乙醇 | CAS号105-56-6 氰乙酸乙酯 | CAS号111222-40-3 2-氨基-5-苯基-1H-吡咯... | CAS号50551-10-5 3-氨基-3-亚氨基丙酸乙酯 | CAS号2148-86-9 Ethyl (5,6-dime... | CAS号34570-17-7 丙二酰脒盐酸盐 | CAS号29182-42-1 2-(2-苯并噻唑)乙酸乙酯 | CAS号32002-24-7 3,3-二乙氧基丙烯酸乙酯 | CAS号7597-56-0 氨基甲酰乙酸乙酯 | CAS号75-00-3 氯乙烷 | CAS号6829-41-0 异亚硝基丙二酸二乙酯 | CAS号57508-48-2 3-脒基丙酸乙酯盐酸盐

β-乙氧基-β-亚氨基丙酸乙酯置于氯化铵体系中,用 乙醇 用作溶剂,化学反应 16.0H,以84%的收率获得3-乙氧基-3-亚氨基丙酸乙酯盐酸盐
参考文献: Biaryl Compounds Useful For The Treatment Of Human Diseases In Oncology,Neurology And Immunology[fr] Composés Biaryliques Utiles Pour Le Traitement De Maladies Humaines En Oncologie,Neurologie Et Immunologie
标题: Biaryl Compounds Useful For The Treatment Of Human Diseases In Oncology,Neurology And Immunology[fr] Composés Biaryliques Utiles Pour Le Traitement De Maladies Humaines En Oncologie,Neurologie Et Immunologie
摘要:本发明提供了作为bruton'S酪氨酸激酶抑制剂的化合物及其组合物,具有适用于同一目的的理想特性.

专利信息

专利号:US-8309540-B2
优先权日:2006-10-24
标 题:HCV NS3 protease inhibitors
发明人：LIVERTON NIGEL J; VACCA JOSEPH P; MCCAULEY JOHN A; ROMANO JOSEPH J; RUDD MICHAEL T
权利人:LIVERTON NIGEL J; VACCA JOSEPH P; MCCAULEY JOHN A; ROMANO JOSEPH J; RUDD MICHAEL T; MERCK SHARP & DOHME
摘要:The present invention relates to macrocyclic compounds of formula (I) that are useful as inhibitors of the hepatitis C virus (HCV) NS3 protease, their synthesis, and their use for treating or preventing HCV infections. (I)

专利号:US-RE50050-E
优先权日:2013-06-21
标 题 :Pyrimidinedione compounds
发明人：OSLOB JOHAN; ANDERSON ROBERT; AUBELE DANIELLE; EVANCHIK MARC; FOX JONATHAN CHARLES; KANE BRIAN; LU PUPING; MCDOWELL ROBERT; RODRIGUEZ HECTOR; SONG YONGHONG; SRAN ARVINDER
权利人:MYOKARDIA INC
摘要:Provided are novel pyrimidine dione compounds and pharmaceutically acceptable salts thereof, that are useful for the treatment of hypertrophic cardiomyopathy (HCM) and conditions associated with left ventricular hypertrophy or diastolic dysfunction. The synthesis and characterization of the compounds and pharmaceutically acceptable salts thereof, are described, as well as methods for treating HCM and other forms of heart disease.

专利号:US-8927569-B2
优先权日:2007-07-19
标 题 :Macrocyclic compounds as antiviral agents
发明人：HARPER STEVEN; SUMMA VINCENZO; LIVERTON NIGEL J; MCCAULEY JOHN A; BUTCHER JOHN W; DI FILIPPO MARCELLO; DI FRANCESCO MARIA EMILIA; FERRARA MARCO; ROMANO JOSEPH J; RUDD MICHAEL T
权利人:HARPER STEVEN; SUMMA VINCENZO; LIVERTON NIGEL J; MCCAULEY JOHN A; BUTCHER JOHN W; DI FILIPPO MARCELLO; DI FRANCESCO MARIA EMILIA; FERRARA MARCO; ROMANO JOSEPH J; RUDD MICHAEL T; MERCK SHARP & DOHME
摘要:A class of macrocyclic compounds of formula (I), wherein R 1 , R 3 , R 4 , R a , R b , A, Z, Y, X, M, W, n and m are defined herein, that are useful as inhibitors of viral proteases, particularly the hepatitis C virus (HCV) NS3 protease, are provided. Also provided are processes 5 for the synthesis and use of such macrocyclic compounds for treating or preventing HCV infection. Formula (I):

专利号:US-2023383342-A1
优先权日:2022-05-31
标 题 :Compositions and methods for nucleic acid sequencing
发明人：WU XIAOLIN; MCCAULEY PATRICK; DHARMARWARDANA MADUSHANI; NIRANTAR SAURABH; GOLYNSKIY MISHA; YANG XIANGYUAN; NEELAKANDAN RAMESH; MACKWORTH BENEDICT; ANASTASI CAROLE; KARUNAKARAN AATHAVAN; VESSERE GERY M; BRACHER DAVID
权利人:ILLUMINA CAMBRIDGE LTD; ILLUMINA SINGAPORE PTE LTD; ILLUMINA INC; ILLUMINA SOFTWARE INC
摘要:Embodiments of the present disclosure relate to kits, compositions, and methods for nucleic acid sequencing, for example, two-channel nucleic acid sequencing by synthesis using blue and green light excitation. In particular, unlabeled nucleotides for incorporation may be used in conjunction with affinity reagents containing detectable labels excitable by blue and/or green lights, for specific binding to each type of nucleotides incorporated.

专利号:US-8377874-B2
优先权日:2006-10-27
标题 :HCV NS3 protease inhibitors
发明人：LIVERTON NIGEL J; VACCA JOSEPH P; MCCAULEY JOHN A; RUDD MICHAEL T
权利人:MERCK SHARP & DOHME; LIVERTON NIGEL J; VACCA JOSEPH P; MCCAULEY JOHN A; RUDD MICHAEL T
摘要:The present invention relates to macrocyclic compounds of formula (I) that are useful as inhibitors of the hepatitis C virus (HCV) NS3 protease, their synthesis, and their use for treating or preventing HCV infections.

专利号:US-4990515-A
优先权日:1989-01-16
标 题:Benzo[1,8]naphthyridine derivatives as antimicrobials
发明人：ANTOINE MICHEL; BARREAU MICHEL; DESCONCLOIS JEAN-FRANCOIS; GIRARD PHILIPPE; PICAUT GUY
权利人:BELLON LABOR SA ROGER
摘要:New benzo[b][1,8]naphthyridine derivatives of general formula (I), in which R is a hydrogen atom or an alkyl, fluoroalkyl, cycloalkyl (3 to 6 C), alkoxy or alkylamino radical or an amine protective radical and either Hal is a fluorine, chlorine or bromine atom and R' is a hydrogen atom or Hal and R' are simultaneously fluorine atoms, their salts, their preparation and the compositions which contain them. These new products can be used as antimicrobial agents for topical application or as synthesis intermediates. (I)