CAS: 1794-84-9; Chloronitromethane

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CAS号85915-53-3 Chloronitroacet... | CAS号82208-51-3 chloronitro-Ace... | CAS号663-08-1 2-nitro-3,3-dif... | CAS号75-52-5 硝基甲烷 | CAS号14011-27-9 ethyl 2-chloro-... | CAS号76-06-2 氯化苦 | CAS号186581-53-3 重氮甲烷 | CAS号34557-54-5 methane | CAS号623-73-4 重氮乙酸乙酯 | CAS号60-29-7 乙醚 | CAS号113-00-8 guanidine | CAS号21272-85-5 硝甲基苯砜 | CAS号1184-89-0 二溴一氯硝基甲烷 | CAS号66073-97-0 4-CHLOROBENZENE... | CAS号625-76-3 二硝甲烷 | CAS号62635-34-1 2-氯-2-硝基乙醇 | CAS号32349-14-7 2-chloro-2-nitr... | CAS号51351-89-4 4-(TOLUENESULPH...

📜氯硝基乙酰氯置于水体系中,用 乙醚 用作溶剂,化学反应生成氯硝甲烷
参考文献:Synthesis Of Chloro-And Dichloronitromethanes
标题:Synthesis Of Chloro-And Dichloronitromethanes
摘要:
Doi:10.1007/bf00954250

专利信息

专利号:US-6198000-B1
优先权日:1997-07-07
标 题:Intermediates useful in the synthesis of quinoline antibiotics
发明人：HAWKINS JOEL M
权利人:PFIZER
摘要:A process for preparing a compound of the formula n wherein R 1 , m, o and p are described below, which comprises adding a base of the formula n wherein R 2 , R 3 and R 4 are as described below, to a solution comprising a compound of the formula n wherein R 1 , m, o and p are as described below, and a halonitromethane of the formula O 2 NCH 2 X, wherein X is a halogen atom dissolved in a non-aqueous inert solvent. The compounds of formula III are useful as intermediates in the syntheses of azabicyclo quinoline carboxylic acids, and their pharmaceutically acceptable salts and prodrugs, having antibacterial activity. This invention also relates to the base of formula IV wherein each R 2 is butyl, R 3 is hydrogen and each R 4 is t-butyl.

专利号:US-5298629-A
优先权日:1992-03-02
标题 :Intermediates in the synthesis of quinoline antibiotics
发明人：BRAISH TAMIN F
权利人:PFIZER
摘要:This invention relates to compounds of the formulae ##STR1## wherein R and X are defined as below. These compounds are useful as intermediates in the syntheses of azabicyclo quinoline carboxylic acids having antibacterial activity.

专利号:US-6057455-A
优先权日:1996-07-09
标题 :Preparation of intermediates useful in the synthesis of quinoline antibiotics
发明人：HAWKINS JOEL M
权利人:PFIZER
摘要:A process for preparing a compound of the formula ##STR1## wherein R 1 , m, o and p are described below, which comprises adding a base of the formula ##STR2## wherein R 2 , R 3 and R 4 are as described below, to a solution comprising a compound of the formula ##STR3## wherein R 1 , m, o and p are as described below, and a halonitromethane of the formula O 2 NCH 2 X, wherein X is a halogen atom dissolved in a non-aqueous inert solvent. The compounds of formula III are useful as intermediates in the syntheses of azabicyclo quinoline carboxylic acids, and their pharmaceutically acceptable salts and prodrugs, having antibacterial activity. This invention also relates to the base of formula IV wherein each R 2 is butyl, R 3 is hydrogen and each R 4 is t-butyl.

专利号:EP-0818445-A1
优先权日:1996-07-09
标 题 :Preparation of intermediates useful in the synthesis of quinoline antibiotics
发明人：HAWKINS JOEL MICHAEL
权利人:PFIZER
摘要:A process for preparing a compound of the formulan nwherein R 1 , m, o and p are described below, which comprises adding a base of thenformulan nwherein R 2 , R 3 and R 4 are as described below, to a solution comprising a compoundnof the formula n nwherein R 1 , m, o and p are as described below, and a halonitromethane of the formulanO 2 NCH 2 X, wherein X is a halogen atom dissolved in a non-aqueous inert solvent.nThe compounds of formula III are useful as intermediates in the syntheses of azabicyclonquinoline carboxylic acids, and their pharmaceutically acceptable salts and prodrugs,nhaving antibacterial activity. This invention also relates to the base of formula IVnwherein each R 2 is butyl, R 3 is hydrogen and each R 4 is t -butyl.

专利号:US-5256791-A
优先权日:1992-03-02
标 题 :Preparation of intermediates in the synthesis of quinoline antibiotics

专利号:CN-1076440-A
优先权日:1992-03-02
标题:Preparation of intermediates in the synthesis of quinoline antibiotics