CAS: 147657-22-5; (1R,3S,Z)-5-(2-((1R,3As,7Ar,E)-1-((2R,5S,E)-5-Cyclopropyl-5-Hydroxypent-3-En-2-yl)-7A-Methyloctahydro-4H-Inden-4-Ylidene)Ethylidene)-4-Methylenecyclohexane-1,3-Diol Hydrate

上下游产品

calcipotriene

卡泊三醇置于氨,水体系中,化学反应 50.0H,反应生成钙泊三醇一水合物
参考文献:Procedure To Obtain Calcipotriol Hydrate
标题:Procedure To Obtain Calcipotriol Hydrate
摘要:获取骨化三醇水合物的步骤.描述了一种用于获取骨化三醇水合物的步骤,该步骤包括在水中无机溶剂存在下反应无水骨化三醇.

专利信息

专利号:EP-1730108-B1
优先权日:2004-03-18
标 题:Stereoselective synthesis of vitamin d analogues
发明人：SABROE THOMAS PETER; CALVERLEY MARTIN JOHN
权利人:LEO PHARMA AS
摘要:The present invention relates to intermediates useful for the synthesis of calcipotriol or calcipotriol monohydrate, to methods of producing said intermediates, and to methods of stereoselectively reducing said intermediates.

专利号:EP-1735276-B1
优先权日:2004-04-02
标题:Novel method for the preparation of intermediates useful for the synthesis of vitamin d analogues
发明人：HANSEN ERIK TORNGAARD; SABROE THOMAS PETER; CALVERLEY MARTIN JOHN; PEDERSEN HENRIK; DEUSSEN HEINZ-JOSEF WILHELM
权利人:LEO PHARMA AS
摘要:The present invention relates to novel methods for the preparation of intermediates which are useful in the synthesis of cacipotriol. The present invention relates further to the use of intermediates produced with said methods for making calcipotriol or calcipotriol monohydrate.

专利号:US-8759555-B2
优先权日:2004-03-18
标 题:Stereoselective synthesis of vitamin D analogues
发明人：SABROE THOMAS PETER; CALVERLEY MARTIN JOHN
权利人:SABROE THOMAS PETER; CALVERLEY MARTIN JOHN; LEO PHARMA AS
摘要:The present invention relates to intermediates useful for the synthesis of calcipotriol or calcipotriol monohydrate, to methods of producing said intermediates, and to methods of stereoselectively reducing said intermediates.

专利号:RU-2378252-C2
优先权日:2004-04-02
标题 :Novel method for synthesis of intermediate compounds, used in synthesis of vitamin d analogues

专利号:US-2007027333-A1
优先权日:2004-03-18
标题 :Stereoselective synthesis of vitamin d analogues

专利号:WO-2005095336-A3
优先权日:2004-04-02
标题:Novel method for the preparation of intermediates useful for the synthesis of vitamin d analogues